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Aggressive fibromatosis is a disease of benign ,clone hyperplasia of fibrocyte.β-catenin,which starts downstream gene transcription,was found concentrated in cell nuclei in sporadic patients.

侵袭性纤维瘤病是一种良性克隆性纤维细胞增生疾病,在散发病人的组织病理切片中发现β-catenin向细胞核内浓聚,即向核内转移启动下游基因转录。

Results ERα immunoreactivity was detected in the nuclei of epithelial cells lining lobules and ducts.The positive cells located in the inner layer of the two epithelial layers in the lobules and intralobular ducts,but in the interlobular ducts the positive cells located in the outer layer.

结果:ERα在小叶上皮细胞和导管上皮细胞的细胞核内检测到,在小叶和小叶内导管分布于上皮细胞的内层,在小叶间导管分布于上皮细胞的外层。

Those with subcellular localization or intranuclear accumulation of beta-catenin had better prognosis than no expression.

细胞内讯息传递之蛋白质β-catenin若保存於细胞膜下或是进入细胞核内,相较於完全不表现者有较佳的预后。

There are two types of maturation according to our observation.One is nucleocapsids obtained its tegument in the nucleus and enveloped from the inner nuclear membrane.Another is nucleocapsids entered cytoplasm through nuclear membrane,then obtained their tegument in the cytoplasm,enveloped from the plasma membrane,finally released by necrosis,exocytosis or other ways.

病毒成熟有两种方式:一为细胞核内核衣壳在核内获得皮层,通过核内膜获得囊膜成为成熟病毒;二为核内核衣壳通过内外核膜进入胞浆,核内和胞浆内的核衣壳在细胞浆中获得皮层,然后在各种质膜上获得囊膜,最后成熟病毒通过细胞破裂或其他方式释放到细胞外。

Proliferating cell nuclear antigen is usually regarded as anindex of determinating cell proliferating and its expression levelin the nuclear is correlated with with the activity of cellproliferation. The activity of tumor cell proliferation can beknown by examinationing PCNA of tumor cells.

增殖细胞核抗原(proliferating cell nuclear antigen,PCNA)常作为测定细胞增殖水平的指标,其在细胞核内阳性表达的高低与细胞增殖活性密切相关,通过检测肿瘤细胞的PCNA ,可了解和评价肿瘤组织的增殖活性。

Protein dynamics in the karyon is important to the nuclear architecture and gene regulation, however, the detail mechanism is still unknown and expected to further study.

细胞核内蛋白质的动态变化对细胞核的结构组成和基因表达的调控都具有重要的意义,但详细的机制还有待於进一步的研究。

In response to TCDD exposure, AhR nuclear translocator forms a heterodimer with the aryl hydrocarbon receptor after the ligand-dependent translocation of AhR to the nucleus, and eventually the complex binds to the xenobiotic response elements, which promote transcription of several specific genes, such as CYP1A1.However, the diverse effects of TCDD could not be simply explained by the AhR pathway.

对於戴奥辛的毒性机制,以往的研究认为与芳香基碳氢化合物受体(arylhydrocarbon receptor-AhR)的活化有关;TCDD 活化了AhR,被活化的AhR 从细胞质转移到细胞核内,在细胞核与另一个蛋白质AhR nuclear translocator形成二聚体,并与DNA 上的xenobiotic regulatory element结合,诱发某些基因(如:CYP1A1)的转译与表现;不过,单从AhR的代谢途径并不能解释所有生物上的毒性现象。

Our study showed that EGFprotein was mainly localized in the cell plasma of distal tubules and Henle'sloops and EGF mRNA was distributed not only in the nucleuses of above sitesbut also in a few nucleuses of interstitial cells and glomerulus cells.

本研究表明EGF蛋白主要位于髓袢和远曲小管细胞胞浆,而EGFmRNA除了位于上述部位的细胞核中外,在少数间质细胞、肾小球细胞细胞核内也有少量表达。

The results showed that the ZNF191fu and ZNF434fu functioned as transcription repressors while the ZNF396fu can only weakly suppress the transcription activity of the reporter, and the ZNF397fu and ZNF447fu showed no signanificant capability of transcription regulation.

而转录因子发挥作用需要进入到细胞核中,因此,我们进一步分析了这些基因的不同剪接本在细胞内定位的情况,结果显示我们所检测的5个成员的nf剪接本都能被相应的fu剪接本带入细胞核内,并且这种作用是通过SCAN结构域所介导的。

In mature stage,the organelle,such as dissociative ribosome,Golgi body,endoplasmic reticulum and nuclear,was disassembled quickly.

在此时期内,筛管内的游离核糖体、高尔基体、内质网、细胞核等细胞器迅速解体消失。

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然而,正如其名字所指出的那样,CD盘不能写,也不能用任何方式改变其内容。

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