细胞核

It was previously shown that MTF-1 rapidly translocates to the nucleus in response to zinc exposure. However, regions within the MTF-1 protein that serve as nuclear localization signal remain unclear.

已知在细胞受到锌刺激后，MTF-1会由快速地由细胞质进入细胞核，然而，MTF-1以何作为核定位信号，至今仍是不清楚的。

Moreover, Par-3 localizes on the membrane when Caco2 or MDCK cells are confluent, but translocates to the nucleus when cells are subconfluent.

此外，Par-3蛋白在Caco2和MDCK细胞高密度时主要定位于细胞膜上，在低密度时主要定位于细胞核中。

In heathlty cells, AIF protein is normally confined to mitochondrial intermembrane space. However, after apoptosis is induced, AIF protein can be released from mitochondria and translocates into nucleus leading by its nuclear localization signal.

正常情况下，AIF蛋白定位于细胞线粒体膜间隙，当有凋亡信号刺激时，AIF分子从线粒体释放到细胞浆，再通过其核定位信号转位到细胞核中，直接引起染色体凝集和DNA的大片段(~50kb)断裂，导致细胞凋亡。

The Hyal-2/WOX1 complex is internalized and translocates to the nuclei, and this complex appears to exert growth suppression in normal epithelial cells.

命名为WWOX、FOR 或 WOX1）这个肿瘤抑制性蛋白质移动过来与 Hyal-2 结合，接下来 Hyal-2/WOX1 complex 深入细胞内部，继而移行进入细胞核，进一步导致正常上皮细胞的生长抑制作用。

Endo G is a mitochondrial DNA enzyme which translocates to nucleus after releasing from mitochondrion and cuts chromatin DNA into nucleosome fragments in a caspase-independent manner.

Endo G是一种线粒体DNA酶，当其从线粒体释放出来之后，可以转位到细胞核，并且以caspase非依赖性方式将染色质DNA剪切为核小体碎片。

The less of E-cadherin in leukemia cells may result in β-catenin translocating to the nu-clear and transcriptional activation of its target genes.

白血病细胞中E-cadherin表达降低或缺失可引起β'-catenin从细胞膜释放并进入细胞核，最终可能会引起β-catenin靶基因的转录。

Positive staining of oxytocin and vasopressin were in the cytosol of the neurons and the former gave less intensity,many positive varicosities for vasopressin were also noticed in neurite.

催产素的免疫阳性产物主要在细胞核周围的胞浆即核周质内，而加压素的免疫阳性物质除了在核周质内有很强的反应外，在突起内也可见很强的免疫反应。

The injured gill cells had a different ultrastructure, with endoplasmic reticulum dilated and vesiculated, mitochondrial cristaes partially disintegrated, gill fibre cuticles denatured and dropped. The ultrastructural damages to hepatopancreatic cells were characterized by the decrease of microvilli, swelling and breaking up of mitochondria, expansion of endoplasmic reticulum, disruption and vacuolization of nucleus, tumefaction of nuclear membrane and increase of lipid droplets. As for the toxicological changes of myocardial cells, the mitochondria were swelling, having a lot of vacuolus and disintegrating, while the myofibrils were irregular with endoplasmic reticulum dissolved.

鳃细胞的损害表现为鳃丝水肿，细胞器溶解，角质层变薄，线粒体、内质网的肿胀、解体；肝胰脏细胞的主要损害特征为肝管微绒毛减少，线粒体水肿解体，内质网扩张，细胞核空泡化，核膜水肿和脂肪滴增加；心脏细胞的毒理变化为线粒体内嵴肿胀、瓦解，肌原纤维不规则，内质网溶解。

Ultrastructure observation revealed that the nuclei became deformed, nucleolus disintegrated and chromatin condensed, the thylakoids of chloroplast swelled, the chloroplast membrane disrupted, cristae of mitochondria disappeared and mitochondria vesiculated.

电镜观察发现，Cd(上标 2+)处理下，细胞核变形，核仁解体，染色质凝集；类囊体片层膨胀，叶绿体双层膜破裂；线粒体中嵴突减少或消失，线粒体空泡化。

Moreover, andrographolide blocked nuclear translocation and DNA binding activity of NF-κB.

此外，穿心莲内酯也会减少 p65 进入细胞核内以及 NF-κB与 DNA 的结合。

The concept of equivalent rotationally rigidity is offered and the formula of rotationally rigidity is obtained.

主要做了如下几个方面的工作：对伸臂位于顶部的单层框架—筒体模型进行分析，提出了等效转动约束的概念和转动约束刚度的表达式。

Male cats normally do not need aftercare with the exception of the night after the anesthetic.

男猫通常不需要善后除了晚上的麻醉。