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To examine the influence of systemic factors on aged progenitor cells from these tissues, we established parabiotic pairings (that is, a shared circulatory system) between young and old mice, exposing old mice to factors present in young serum. Notably, heterochronic parabiosis restored the activation of Notch signalling as well as the proliferation and regenerative capacity of aged satellite cells.

为了查明系统因子对来自这些组织的衰老祖细胞的影响,我们在幼鼠和老鼠之间建立了共生态配对试验(即:一种共享的循环系统),给老鼠输入含有年轻因子的血浆,奇怪的是,异时性共生态细胞Notch信号重新激活,同时恢复了衰老干细胞增生和再生能力。

Objective To evaluate the role of cytokines in the pathogenesis of COPD.

目的 探讨 3种细胞因子和炎症细胞在慢性阻塞性肺疾病发病机制中的作用。

Otherwise phagocyte and B cell could only stimulate activated and memory T cell, so DC are considered to be the initiation of organism immunity, which play a unique role in inducing the immunity.

而吞噬细胞、B细胞仅能刺激已分化的或记忆性T细胞,因此DC是机体免疫反应的初始者,在免疫应答的诱导中具有独特的地位。

The number of Bcl-2 positive cells in phenobarbital sodium, A. gramineus, and α-asarone groups was more than that of epilepsy control group significantly (P.01). But the number of Bax positive cells was no markedly difference among the each groups.

其中,苯巴比妥钠组、石营蒲组、α-细辛醚组Bcl-2阳性细胞数量增加较致痫对照组显著(P.01);Bax阳性细胞数量各致痫组之间无显著性差异。

Western blotting was applied to the phosphorylation of PKGⅡ substrate vasodilator-stimulated phosphoprotein to represent the activity of the kinase.

有报道指出,PKGⅠ和PKGⅡ在亚细胞定位、组织分化和功能上有所不同, PKGⅡ是膜结合酶而PKGⅠ是细胞溶质性酶[2,3]。

Objective? To establish stable expressing system of Borna disease virus phosphoprotein in PC-12 cells, and then study its influence on cell proliferation of PC-12 cells.?Method?

建立博尔纳病病毒磷蛋白在神经源性PC-12细胞内的稳定表达体系,初步探讨博尔纳病病毒磷蛋白对PC-12细胞的生长是否有影响。

Results: The direct signs (such as mural nodule of cystic lesion, solid neoplastic component of solid type、 mixed type tumors enhanced markedly; vascular void signal show with in the tumors) and indirect sign (solid neoplastic component of the tumors close to or adhesion to a pia mater) have some specific manifestations on MR imaging...

结果:血管母细胞瘤的直接征象(如囊肿型的瘤结节,实质性、混合性肿瘤的实质部分明显强化;瘤内出现血管流空信号)及间接征象(肿瘤实质部分邻近软脑膜或与软脑膜有粘连)具有一定的特异性。结论:MR对诊断血管母细胞瘤具有较高的价值。

This paper describes an inhibitory effert of GABA on the incorporation of ̄3H-TdR into rat anterior pituitary cells in static primary monolayer cultures. The action was antagonizable by picrotoxin.

本实验利用原代细胞培养体系,观察到GABA对大鼠垂体前叶细胞的氚标胸苷(3H-TdR)基础掺入率有明显的抑制性效应,且可被印防己毒素所反转。

Tumor necrosis factorαis a pleiotropic factor involved in diverse cellular responses, including inflammation,apoptosis and necrosis.

肿瘤坏死因子TNFα是一个多效性细胞因子,参与调节炎症反应、细胞凋亡和坏死等。

Both benign and malignant endocrine neoplasms demonstrate some degree of cellular pleomorphism , so it is not easy to tell benign from malignant on histologic grounds alone.

内分泌系统的良恶性肿瘤的瘤细胞均呈现一定程度的细胞的异型性,因此,在组织学上很难区分肿瘤的良恶性。

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