细胞性

In fact most cases of metaplastic carnoma belong to the spectrum of basal-like carcinomas based on the definition, such as spindle cell ca, squamous cell ca, adenosqumous.

实际上，按照定义大多数化生性癌属于基底细胞样癌的范围，如：梭性细胞癌、鳞状细胞癌和腺鳞癌。

Results Among the 52 cases, 30 cases were confirmed to fibrosarcomas, which were identical with primary dingnoses;22 cases were revised to malignant fibrous histocytoma (8 cases), malignant nerve sheath tumor (4 cases), monophasic spindle cell synovial sarcoma (3 cases), leiomyosarcoma(3 cases), rhabdomyosarcoma(2 cases) and abdominal desmmoid tumor (2 cases). Of the 18 cases, only two cases were misdiagnosed and were revised to malignant fibrous histocytoma and spindle cell synovial sarcoma, respectively.

结果：1980年前52例中维持原诊断30例，修改诊断22例(42.3%)，分别为恶性纤维组织细胞瘤8例、恶性神经鞘膜瘤4例、单相性梭形细胞滑膜肉瘤3例、平滑肌肉瘤3例、横纹肌肉瘤2例、韧带状纤维瘤2例；1980年后纤维肉瘤18例中，维持原诊断16例，修改诊断2例(11.1%)，分别为恶性纤维组织细胞瘤和滑膜肉瘤各1例。

Analysis of patient's primary leukemia blasts revealed that those carrying the t(8;21) generating AML1/ETO, the most common acute myeloid leukemia-associated fusion protein, display low levels of a microRNA-223 (miR-223), a regulator of myelopoiesis.

对原发性白血病的胚细胞进行分析发现具有 t （8；21）能够产生 AML1/ETO 蛋白，而这种蛋白是急性髓性白血病相关融合蛋白中最常见的一种，这样的白血病胚细胞具有微小 RNA-223（ miR-223）的低表达， miR-223是骨髓细胞生成的调节因子。

To address this question in an unbiased and genome-wide manner, we developed a new method, methylation-specific digital karyotyping, and applied it to epithelial and myoepithelial cells, stromal fibroblasts from normal breast tissue, and in situ and invasive breast carcinomas.

为了能无偏向地并在基因组范围解答这个问题，我们开发了一种新的方法——甲基化特异性数字染色体组型，并将这一方法应用于上皮细胞和肌肉上皮细胞、正常乳腺组织来源的基质成纤维原细胞、原位及侵入性乳腺癌细胞。

Immunohistochemically, cells in myoid/myofibroblastic areas showed positive staining for α-SMA, MSA and vimentin, but negative for desmin and CD34. Electron microscopic study displayed the presence of microfilament bundles, focal dense bodies and micropinocytic vesicles, consistent with those of myofibroblasts.

免疫组织化学标记显示肌样区域细胞表达α-平滑肌肌动蛋白和肌特异性肌动抗原，不表达CD34；电镜观察证实细胞含有质膜下微丝束、局灶性致密体及微胞饮囊泡样结构，与肌纤维母细胞相一致。

In contrast, 11/15 primary glioblastomas contained a significant CD133 subpopulation that displayed neurosphere-like, nonadherent growth and asymmetrical cell divisions yielding cells expressing markers characteristic for all three neural lineages.

相反，15个原代胶质母细胞瘤中有11个含有明显的CD133阳性亚群，呈神经球样，非附着性生长和非对称性细胞分裂，后者产生表达所有三种神经细胞系的特征标志物的细胞。15

These nonmalignant cells, such as stromal fibroblasts and bone marrow-derived cells, have been shown to be capable of promoting tumor growth and metastasis.

这些非恶性细胞如基质成纤维细胞和骨髓源性细胞已被证明能够促进肿瘤的生长和转移。

Chronicity maybe result from many factors with complex mechanism.HCV may evade the host immune surveillance due to the hypermutation of HCV gene; HCV has the nature of pantropic,the tissues outside liver can provide virus for repeatedly infection of liver; The HCV receptors,such as CD81,LDL receptor,scavenger receptor B type I,L-SIGN,DC-SIGN and so on,may influence organism humoral immunity and the cellular immunity function in different degrees; HCV infection also may cause the reduction of quantity of organism immune cell or functional defect,low response of humoral immune response,tolerance of cellular immunity,then,the host finally transforms into chronic infection condition.

其慢性化的机制非常复杂，是由多个因素造成的，HCV因其基因高变性可以逃避宿主的免疫监视；HCV具有泛嗜性，肝外组织又可为肝组织的反复感染提供病毒来源；CD81、LDL受体、清道夫受体B类Ⅰ型及L-SIGN、DC-SIGN等HCV受体又可不同程度地影响机体的体液免疫和细胞免疫功能；HCV感染亦可直接导致机体免疫细胞数量减少或功能缺陷，体液免疫应答水平低下、细胞免疫耐受，宿主最终转变为慢性感染状态。

In addition, we have found other cellular sources like periportal fibroblasts or bone derived fibrocells.

另外，我们发现还有其他细胞来源例如门静脉周围成纤维细胞或者骨源性纤维细胞。

Cell-based therapy is a promiseful option.This review will focus on the present status of cell-based therapy.Myoblast transfer therapy is hindered by minimal distribution of cells after injection,immune rejection,and poor cell survival.The drawback of bone marrow...

成肌细胞移植面临的主要限制是注射后细胞分布差，免疫排斥和细胞存活率低；骨髓干细胞移植需要解决横向分化的低效率问题；而肌源性干细胞看来能更有效地再生表达dystrophin的肌纤维。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。