细胞性

Although, in our study the functional characteristics of these T cells was not investigated, we can speculate that in HBsAg inactive carriers, a dynamic population of HBV specific T cells, both in the liver and periphery exists, that is able to produce antiviral cytokines (i.e. IFN-gama) and thus suppress HBV replication without cytolytic liver damage.

我们虽然没有研究这些细胞的功能特征，但是可以推测：非活动性乙肝病人机体内，有一个具有动态数量的HBV特异性T细胞群，在肝组织和外周都存在，它们能够产生抗病毒因子抑制病毒的复制，同时不造成肝细胞损伤。

Methods: The HUVEC was incubated with exogenous AGEs for 12 h, and ergamine and catalase were used as control. The activity, monolayer permeability, apoptosis rate, biochemical indexes and morphous changes were detected in HUVEC.

外源性AGEs与HUVEC共孵12h，以组胺和过氧化氢酶为对照，检测内皮细胞的活性、单层通透性、凋亡率及细胞培养液生化指标，并且观察内皮细胞形态学改变。

Observation under Transmission Electron Microscope was carried out and growth curve of E. coli was ploted out. It was indicated that PSPPs might change the permeability of cell membrane, make cell excrescent and inhibit cell division.

透射电镜观察和大肠杆菌生长曲线表明，该色素的抑菌作用可能是通过增强细胞膜的通透性，使细胞异常生长，抑制对数生长期的细胞分裂，使细胞质稀薄、细胞解体。

Extraperiosteal ossification of bone injury induced by fluoride is closely associated with fibroblasts which belong to inducible osteogenic precursor cell in bone, they have osteogenic function under special conditions.

氟性骨损伤骨周化骨与成纤维细胞密切相关，在骨周组织中，成纤维细胞(fibroblast， FB)属于诱导性骨祖细胞范畴(inducible osteogenic precursor cell， IOPC)，在特殊条件下具有成骨功能。

We have performed systematical studies on intrauterine transmission of hepatitis B virus and our studies suggested that HBV may occur through progressive infection of different placental layers until the virus reaches the fetoplacental circulation, which is the named "transplacental cellular traffic" except through placental tears with transfusion of infected maternal blood into the fetal circulation, which is the named "hematogenous transmission".

我室近年来对HBV宫内传播进行了系列研究，发现了胎盘在宫内传播中的作用，并提出了HBV宫内传播机制的假设：除血源性途径外，还可通过HBV在胎盘组织内的&细胞传递&途径，即HBV可以从母体蜕膜细胞通过&逐层转移&至胎儿绒毛毛细血管内皮细胞，导致胎儿感染。

Cases healthy subjects served as control. In addition, density of glomerular matrix membrane and quantity of cell in glomeruli were measured with CMIAS image analysis system by computer. Global sclerosis, cellular crescents, fiber or fibrocellular crescents were measured with Memphis scope. Tubulointerstitial lesions were examined with semi-quantitative grades (including O-III grades).Results Compared to normal control, there was a significant increase of urinary TGF-betaK IL-6 and Col-lV levels in patients with IgAN (p. 01). There were also significantly positive correlation between the levels of urinary TGF-betaK Col-IV and density of glomerular matrix membrane ., interstitial fibrosisp.

采用酶联免疫吸附法测定尿TGF-β1(Transforming growth factor-β1)、尿IL-6(interleukin-6)和尿Col-Ⅳ(type Ⅳ Collagen)；采用免疫组织化学法检测肾组织TGF-β1、Col-Ⅳ表达；应用CMIAS多功能真彩色病理图像分析系统对肾小球基质基底膜面密度和细胞个数进行半定量测定；对球性硬化、节段硬化、细胞新月体及纤维或纤维细胞新月体所占肾小球百分数和肾小球IgA沉积免疫荧光强弱的判断采用Memphis法进行评分；肾小管间质病变程度采用光镜下半定量分级法(包括0-Ⅲ级)。

Theurinary IL-6 level positively correlated with density of glomerular matrix membrane, global sclerosis, fiber or fibrocellular crescents and interstitial fibrosis (p. 05). According to the degree of density of glomerular matrix membrane and interstitial fibrosis, urinary Col-IV level had better correlation than urinary TGF-betal and IL-6 levels.In IgAN, Col-IV showed increased expression in diseased renal tissue whereas the site of expression of TGF-betal was mainly localized within the cytoplasm of tubular epithelial cells. Interstial expressionwas also present but glomerular TGF-betal expression was found only in patients with heavy mesangial proliferation. There was a significant correlation between glomerular positivity for Col-IV and severity of histological damage. There was also a significant correlation between positivity for TGF-betal and Col-IV in the tubular epithelial and interstitial lesions. In contrast, there was no ralationship between glomerular positivity for TGF-betal and severity of histological damage.The urinary TGF-betal level paralleled tubular TGF-betal expression.

结果 ①IgAN患者尿TGF-β1、IL-6、Col-Ⅳ水平较健康人明显增高(P＜0.01)，该变化与血中的浓度无关(P＞0.05)；②尿TGF-β1水平与小管间质TGF-β1阳性表达呈正相关(P=0.000)，而与小球TGF-β1阳性表达无关(P＞0.05)，尿Col-Ⅳ水平与小球和小管间质Col-Ⅳ阳性表达均呈良好的相关性(P＜0.01)，还与小管间质TGF-β1阳性表达呈正相关(P＜0.05)：③小球Col-Ⅳ阳性表达与肾组织慢性病变密切相关(P＜0.05)，小管间质Col-Ⅳ和TGF-β1阳性表达均与肾小管间质病变呈良好的相关性(P＜0.01)，而小球TGF-β1阳性表达与肾组织损伤无关(P＞0.05)；④尿TGF-β1、Col-Ⅳ水平与肾小球基质基底膜面密度、小管间质病变呈正相关(P＜0.01)，与小球内细胞数呈负相关(P＜0.05)，该结果与其在组织中的表达一致；尿IL-6水平浙江大学硕士学位论文尿TGF一B一、IL一6和Col一IV在IgA肾病中的应用价值与基质基底膜面密度、球性硬化、纤维或细胞纤维新月体所占肾小球百分数及小管间质病变均有显著的相关性(F.05)；在轻度肾病理损伤时，尿'l'G卜pl、I卜6、Col一IV水平即升高，而尿Col一W在反映细胞外基质积聚和间质纤维化程度上比尿TGF一pl和IL一6有更好的相关性。

Results The results indicated that the cultured human alveolar bone origin cells from 3 patients could successfully express the osteoblasts phenotype in single layered culturing after stimulated by β-glycerophosphate and Dexamethasone.

结果自3人下颌齿槽骨分离培养的齿槽骨细胞在加入β-磷酸甘油和地塞米松刺激的体外培养条件下，均可成功表达成骨细胞的表现型，与同源成纤维细胞相比，差异有显著性(P.05)。

The treatment with dendritic cell vaccine was potent in the control of lung cancer hematogenous metastasis.

树突状细胞疫苗治疗能够有效地清除血源性播散的肺癌细胞，其抗癌机理是形成强有力的特异性细胞免疫应答。

The shortage of this way was that feeder cells could be passaged together with hESCConclusion HAFi could replace MEF as feeder layer to support the long-term culture oftwo Chinese human embryonic stem cell lines. This could remove the cells of animal originand heterogenetic pollution in the culture system. It also reduced the culture of primarycells and solved the instability caused by different batches of primary cells.

结论HAFi细胞可以用做两株中国人胚胎干细胞培养的饲养层，取代MEF后解决了动物源性细胞混杂和异源污染问题，省却了饲养层原代细胞的培养步骤同时解决了由不同批次饲养层差异带来的培养体系的不稳定。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。