细胞性

Giant cell tumor of bone is a kind of common bone tumor,which has characteristics of high recurrence rate and invasion.recently,tumor vessel angiogenesis has been the warm spot of research.genesis,development and metabasis of solid tumor have close relationship with tumor vessel angiogenesis; extracellular matrix degradation is the key point for tumorous infiltration and metabasis;the significant biology characteristic of tumor cell is the disorder of tumor cell differentiation and apoptosis.the correlated research has very important significance for judging gct prognosis and guiding therapy.

骨巨细胞瘤（giant cell tumor of bone，gct）是一种常见骨肿瘤，由于其高复发率和强侵袭性，备受临床骨科工作者的关注。骨巨细胞瘤血管生成是近年来研究热点，实体瘤的发生、发展及转移与肿瘤的血管生成密切相关；细胞外基质降解在肿瘤的浸润和转移中起到关键作用；肿瘤细胞的分化凋亡障碍与无限增殖能力是肿瘤细胞的重要生物学特征。骨巨细胞瘤生物大分子研究的不断深化对判断gct的预后及指导治疗有重要意义。

Results There were characteristic changes in cartilaginous tissue in OA, such as rough cartilaginous surface, irregular arrangement, decrease in number, degeneration and necrosis of chondrocyte, and cell cluster existed. The thickness and groundsubstance of cartilage in OA was thinning and uneven, and metachromatism could be seen.

结果 OA软骨组织表面粗糙不平，软骨细胞排列紊乱，数目减少，有细胞成簇现象，可见软骨细胞变性、坏死，软骨厚度变薄，基质染色不均匀，有异染性。

To our knowledge, this is the first report of the 1H-NMR detection of apoptosis which is closely associated with the increase in methylene resonance signal intensity in plants.

说明亚甲基信号强度的增加是动、植物细胞凋亡过程中所具有的共同特征，1H-NMR技术提供了一种精确可靠的分析植物细胞凋亡的手段，同时由于它所具有的非侵害性的特点，可能在揭示细胞凋亡机制的研究中具有一定的意义。

Results Mosaicism analysis was performed on 14 normal fertilized embryos, which had more than two cells. Nine embryos had sex chromosome mosaicism. XO in male and female embryos cells were 12%and 14%respectively.

结果 有两个细胞以上的14个正常受精胚胎中9个胚胎有不同程度的性染色体嵌合，其中男性胚胎41个细胞中XO有5个，占12%；女性胚胎28个细胞中XO有4个，占14%。

Nine embryos had sex chromosome mosaicism. XO in male and female embryos cells were 12% and 14% respectively. Conclusion Identification of sex by FISH analysis of a single cleavage cell is accurate, and sex chromosome mosaicism will not affect preimplantation gender diagnosis.

结果 有两个细胞以上的14个正常受精胚胎中9个胚胎有不同程度的性染色体嵌合，其中男性胚胎41个细胞中XO有5个，占12%；女性胚胎28个细胞中XO有4个，占14%。

The apoptosis reaction was measured by viability curve, morphology of cells, DNA fragmentation assays and cell flow cytometry analysis after cells were induced by NaBu and serum deprivation.

利用生存曲线、细胞形态学观察、DNA片段分析和流式细胞分析来测定NaBu和无血清DMEM诱导后细胞凋亡的反应性。

In contrast, nasal administration of a mixture of MBP6886 and 8799 completely blocked gpMBPinduced EAE even at lower dosage than being used alone. Rats tolerized with MBP6886+8799 nasally showed decreased T cell responses to MBP, reflected by lymphocyte proliferation and IFNγ ELISPOT assays.

淋巴细胞增殖实验和IFNγ ELISPOT检测显示，与鼻黏膜给予大鼠MBP110128组相比，鼻黏膜给予大鼠MBP6886+8799可降低T细胞对于MBP的反应性，淋巴结单核细胞中表达IFNγ和TNFα mRNA的细胞数减少，而两组表达TGFβ及IL4 mRNA的淋巴细胞数都低。

Two genes which were differentially expressed before and after ATRA treatment have been partly cloned, and one corresponds to a sequence known gene DPH2L with unknown function, which was first isolated from the critical region of deletion on chromosome 17p13.3 in human ovarian carcinoma, and regarded as a candidate tumor suppressor gene.

它的降调节可能参与了从细胞生长到分化／凋亡的转换过程。另一个克隆RAa7是一个未曾报道的新序列，在ATRA或4HPR反应性细胞中呈上升或下降调节，提示该基因可能也参与了细胞过程转换的调节。

These results indicated that olaquindox could inhibit cell growth, destroy subcellular organelle in cell ,e.g.

各检测结果表明喹乙醇能够抑制细胞的生长，损伤细胞内的亚细胞器，破坏细胞膜的完整性，增加其通透性。

Ransforming growth factor beta TGF-β is a potent growth suppressor of normal epithelial cells. However, many types of invasive cancer cells (e.g. breast cancer frequently overproduce TGF-β to enhance their growth and metastasis. Quite frequently, these cells do not possess a functional type II TGF-β receptor, indicating an aberrant TGF-β signaling is responsible for promoting cell growth.

Transforming growth factor beta 对於正常的上皮细胞是一个很强的生长抑制因子，然而，许多种具有蔓延侵犯性的癌细胞常常是表现大量的 TGF-β来促进细胞生长与转移，这些癌细胞通常不表现具有功能性的第二型 TGF-β receptor，显示有另类的 TGF-β讯息传递可以促进细胞生长。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。