细胞性

Leptin activates several singal transduction pathways, can regulate ingestion and energy consumption, and enhance cell growth and hemopoiesis .It also can promote cell proliferation and differentiation, and enhance angiogenesis and regulate immunization.

瘦素通过与其受体的结合，活化细胞内多条信号转导通路，在调控摄食和能量消耗，促进细胞生长、造血等方面起重要作用，同时在促进细胞增殖分化、增加细胞侵袭性、促进血管形成和调节机体免疫等方面起作用。

Hypoxia induces the resistance of tumor cells[4];and the heterogeny of solid tumors result in the appearance of subpopulations of differentproliferative potency in the same tumor tissue, so that the target cells sensitive to cell cyclespecific drug are reduced.

目前有研究认为：实体瘤部分细胞缺氧和肿瘤组织的异质性可能是导致肿瘤对放疗和化疗产生耐受的主要原因之一，缺氧可以诱导肿瘤细胞对放疗和化疗的耐受性[4]，实体肿瘤的异质性可使同一瘤组织内具有不同增殖潜能的癌细胞亚群存在，导致细胞周期特异性化疗药物作用的靶细胞减少。

CD44 is a single strand glucoprotein family encoded by single gene on the memebrane surface with high heterology,which can mediate adhesion between cell and cell as well as cell and extracellular matrix.Its different splicing variants will result in the variety of its gene products.Especially,its splicing varant V6 (CD44v6) is condided to have oncogenicity.CD44v6 takes part in the genesis and development of tumor at some certain and is one of prognostic factors.So it will be the marker indicating tumor development.

CD44是由单一基因所编码的具有高度异质性的单链膜表面糖蛋白家族，介导细胞与细胞、细胞与细胞外基质之间的黏附作用，其拼接变异体的不同构成了其基因产物的多样性；尤其拼接变异体V6(CD44v6)被认为具有致瘤性；CD44v6在一定程度上参与了肿瘤的发生发展，是预后因子之一，并且可能作为肿瘤进展的标志物。

Results The p53 gene mutation rate of colorectal cancer was 50%. The rate of apoptosis of tumor cells having mutation of p53 gene (22.11%) was much lower than that having no p53 mutation (40.57%, P＜0.05). Heteroploid cells had been found in 10/13 tumor samples with p53 gene mutation and 6/13 samples without p53 mutation (P＜0.05). The rate of apoptosis had no difference between the heteroploid cases and diploid cases.

结果 大肠癌标本p53基因突变率为50%；其中突变组肿瘤细胞凋亡率(22.11%)明显低于未突变组细胞凋亡率(40.57%)，(P＜0.05)；突变组异倍体细胞百分率(占76.9%)明显高于未突变组(占46.2%)，(P＜0.05)；异倍体肿瘤细胞凋亡率为34.0%，二倍体肿瘤细胞凋亡率为40.7%，二者差异无显著性(P＞0.05)。

Four of12patients with non-leukemia were heteroploidy,2of4were precancerous lesion.The S%of marrow cell of leukemia was significant lesser than that of control.Three acute lymphocytic leukemia were got CR,and its S%was more than that before therapy.

白血病组骨髓细胞S%明显低于对照组。3例接受治疗的急性淋巴细胞性白血病患儿达到完全缓解后，其S%明显高于治疗前，非白血病组的骨髓细胞周期与正常对照组差异无显著性。

It is with printing and section contrast, 124 smear have nuclear cell to decrease in, 58.9% decrease with the 66.1% positive that it is a holiday, common by accident for; of bring down of aplastic anemia, hematopoiesis printing and section cell quantity increase examine disease in, smear still has 26% decrease with the 36% negative that it is a holiday, common disease or conclusion are grow in quantity of red blood cell of lienal function hyperfunction, true sex disease, special the; such as disease of grow in quantity of the plaque that send a gender printing and section cell bring down person in, smear is accorded with rate (91.2% with 97.9%), and in the person that smear cell increases, printing and section are accorded with rate (95% with 100%) all tall.

以印片和切片为对照，124例涂片有核细胞减少中，58.9%和66.1%为假阳性减少，常见误诊疾病为再生障碍性贫血、造血减低；而印片和切片细胞量增加中，涂片仍有26%和36%为假阴性减少，常见疾病或结论为脾功能亢进、真性红细胞增多症、特发性血小板增多症等；印片和切片细胞减低者中，涂片符合率(91.2%和97.9%)，以及涂片细胞增加者中，印片和切片符合率(95%和100%)均高。

An early event in a cellular heat shock response is the transmittance of stress signal from cell surface into the interior and the...

在细胞应答热休克过程中最早期的事件是将胁迫信号从细胞表面传至细胞内，从而诱导热休克蛋白的合成使细胞产生对热的耐受性。

Methods 40 healthy adult mice were randomly divided into control group, CTX immune-suppressed group, Fb treated group, Fb combined with CTX treated group. The influences of Fb in NK cell activity were determined by the method of NK mediated cytotoxicity test;the multiplicative capacity of lymphocyte was assayed by lymphocyte transformation rate of T cell,and the mice spleen T lymphoblast multiplication analytical method was used to measure the IL-2 level.

健康成年小鼠40只，随机分为对照组、环磷酰胺免疫抑制组、黄蘑碱溶性多糖活性组分正常小鼠给药组和Fb环磷酰胺伍用给药组，采用NK细胞介导的细胞毒试验测定自然杀伤细胞的活性，淋巴细胞转化试验测定T淋巴细胞增殖功能，鼠脾T淋巴母细胞增殖分析法测定白细胞介素2（IL-2）的活性，观察Fb对各组小鼠免疫指标的影响。

PartⅠ/chapter 3 The viability of cultured cerebral endothelial cells was determined by measuring the release of intracellular enzyme lactate dehydrogenase by nonviable cells with increased permeability.

第一部分第三章乳酸脱氢酶（1actate dehydrogenase，LDH）是一种细胞内酶，当细胞失去活力膜通透性增加时即释放到细胞外。本文通过测定释放到培养液中的LDH的量来测定牛脑微血管内皮细胞的活力。

On the Contrary, there was no obviously different in low group.? Observed by electron microscope: The wider of synaptic cleft was increasing, the posts nutpick membrane was thinner, and the synapse I activity area was decrease, all these have significant different from that of control group in high and middle group, But no obviously change in low group.

灌酒精90天后，与对照组相比，胶质细胞纤维酸蛋白免疫反应强度增强及反应性胶质细胞的平均相对密度升高，中、高浓度组有显著性差异（p＜0.01），而低浓度组无明显变化。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。