细胞学的

The results showed that LRK could significantly inhibit the mammary hyperplasia caused by estrin, reduce the content of serum 〓, raise P level, promote the production of DA in hypothalamus and mammary tissue, decrease the release of 5-HT, inhibit the secretion of serum PRL, reduce the sensitivity of mammary tissue to estrin and progestogen, prevent the expression of mammary tissue on PCNA, the effect was equal to triphenylamine oxide, obviously superior to the control group of Ru Zeng Ning.

通过实验研究，建立了具有肾虚肝郁证侯群的乳腺增生病理模型，利用免疫组化技术、图像分析系统、荧光分光光度法、放射免疫法等现代医学研究方法，从病理形态学、医用体视学、神经内分泌学、阴道细胞学等方面，观察了利乳康口服液对模型动物整体状态、乳腺组织病理形态、血清激素、神经递质以及卵巢功能的影响，结果表明利乳康口服液能明显抑制雌激素引起的乳腺组织增生，降低血清E〓含量，升高P水平，促进下丘脑及乳腺组织中DA的产生，减少5-HT释放，抑制血清PRL分泌，降低乳腺组织对雌、孕激素的敏感性，阻止乳腺组织PCNA的表达，其效应与三苯氧胺相当，明显优于乳增宁对照组；另外，利乳康口服液还能缓解模型动物肾虚肝郁证侯群，增加其体重，调节其整体状况，改善模型动物不规则动情周期，减轻其子宫及卵巢的病变，抑制子宫内膜的过度增长，调节卵巢功能，揭示了中药利乳康口服液对神经内分泌和卵巢功能的整体调控作用，以及对本病发生、发展的预防作用

"Spermatogenesis is a long and complex process controlled by multiple interacting mechanisms, and there is a general consensus on the need for FSH in the regulation of this process," write Carlo Foresta, MD, and colleagues from the University of Padova in Italy.

精子的生成是一个很长且很复杂的过程，它是由多种彼此作用的机制控制的，在这个过程中，一般都一直需要卵滤泡刺激素的作用，」意大利Padova大学的Carlo Foresta医师及其同事写道：「从睾丸细胞学分析的结果可以看到，采用100 IU剂量的重组人卵滤泡刺激素隔日使用，以刺激精子产生的过程，同时，还可以增加射出的精子的数目，并加强抑制素B的分泌。

This course systematically describes the structure and function, transmission, expression and regulation, and evolution of genetic materials, covering basis of cytology for inheritance, molecular basis of genetic materials, Mendel's principles of inheritance, linkage and sex linkage, genemutation, variations in chromosome structure and number, quantitative genetics, inbreeding and heterosis, inheritance of bacteria and viruses, extranuclear inheritance, gene engineering, genomics, gene expression and regulation, developmental genetics, population genetics and evolution.

本课程全面系统地介绍遗传物质的结构与功能、遗传物质的传递、遗传物质的表达与调控、遗传物质的进化等，包括遗传的细胞学基础、遗传物质的分子基础、孟德尔遗传、连锁遗传和性连锁、基因突变、染色体结构变异、染色体数目变异、数量性状的遗传、近亲繁殖和杂种优势、细菌和病毒的遗传、细胞质遗传、基因工程、基因组学、基因表达的调控、遗传与发育、群体遗传与进化。

The HPV positivity amongst the group of women with no cervical abnormality was 43%, while that in women with cervical dysplasia and cervical cancer was 81.2% PCR products from 89 HPV positive cases were genotyped by LiPA, of which 49 cases were single HPV infected concerning 11 different HPV types and the commonest type was HPV-16, occurring in 25(51%) of all single HPV infected cases. The other 40 specimens contained multiple HPV types comprising 16 different HPV types. Although double infections(n=25) prevailed, triple(n=9),quadruple(n=3) and quintuple(n=3) infections were also found. PCR products of four HPV positive cases failed to be classified by LiPA. Sequencing analysis revealed that these 4 cases were HPV-66 which was not included in LiPA probes. Follow-up data of 12 cases confirmed the HPV genotyping results. Conclusion The LiPA for HPV genotyping is easy to perform.

结果 155例妇女子宫颈刮片中HPV DNA检出率为60%，其中在宫颈细胞学检查正常或仅有炎症病变的妇女中HPV DNA阳性率为43%，而在宫颈细胞增生不良或宫颈细胞癌的妇女其阳性率为81.2%。93例HPV阳性的标本中，89例利用LiPA成功地作出了基因分型，其中单独一型HPV感染为49例，涉及11种不同基因型HPV，最常见的型别为HPV 16，占单独感染的51%(25/49)；另40例为不同型别HPV重叠感染，涉及所有16种HPV基因型别，二重感染占主导地位(n=25)，同时也检测出其它多重感染。4例HPV阳性的标本应用LiPA未能作出基因分型，DNA序列分析显示这4例为HPV 66感染，此型别不包括在LiPA所标记的探针内。12例随诊资料显示了LiPA的物异性及高度的重复性。

To summarize molecular, morphology, chromosome and pollen characters, the conclusion was reached that Epimedium was an nd monophyletic taxon. To divide the genus into any groups would be artificial. It is proposed that the disjunction by space, climate and seas were the main reason of respectively differentiation of each group by the view of geographic and climate changes in the temperate zone of the world. Because of its evolution-conservation, the disjunction did not bring about obvious divergence on the level of molecular and morphology.

综合分子特征和形态、细胞学、孢粉学等性状，提出淫羊藿属是一个进化上极为保守的、自然的单系的植物类群，进行属下任何阶元的划分都将是人为的，从旧世界温带的地质变化及气候变迁的角度推测，空间、气候和海洋的隔离是产生类群各自分化的主要原因，但由于其进化上极度保守，这些隔离尚未产生出类群间形态上和分子水平上的明显趋异。

In most cases, the diagnoses were based on the histopathologic examination of tissue obtained ia laparotomy (7 patients, including 3 for failed medical treatment of pelic inflammatory disease, 3 with assumed mucinous oarian tumors, and 1 with an oarian tumor) or peritoneoscopy (6 patients); cytologic examinations diagnosed TB for the others (3 patients).

大多数病例的诊断是基于剖腹手术（7例，包括3例按盆腔感染治疗失败的病人，3例怀疑粘连性卵巢肿瘤病人和1例怀疑卵巢肿瘤的病人）或腹腔镜（6例）所获取组织的病理学检查，另外3例的诊断是根据细胞学检查诊断TB的。10例病人中，4例先前有肺TB，3例子宫内膜TB。

Results:①The amount of human colon carcinoma cell line SW480 treated by quercetin decreased. The morphology of partial SW480 cells was shrunk volume, integrated cell membrane, condensed cytoplasm, pyknotic chromatin, nuclear fragmentation. Apoptotic Corpuscles were found by electron microscope.②MTT colorimetric assay showed quercetin inhibited the growth of human colon carcinoma cell line SW480 in a time- and dose-dependent manner when the concentration of quercetin was 30、60、90μmol/L.③Flow cytometry analysis showed the cell cycle of SW480 cell was restricted in G1/S. G0/G1 phase rate increased and S phase rate decreased with increasing concentration of quercetin and time lasting.④ Zymogram analysis assay showed the secretion of matrix metalloproteinases in human colon carcinoma cell line SW480 treated by quercetin decreased. With increasing concentration of quercetin, the secretion of MMP-2 and MMP-9 decreased.⑤Immunohistochemistry method demonstrated the position expression of Cathepsin-D in SW480 cell was suppressed by quercetin in a time- and dose-dependent manner.

研究结果：经槲皮素处理的人结肠癌SW480细胞数量减少，部分细胞体积缩小，细胞膜完整，胞浆浓缩，核染色质固缩，细胞核碎裂，形成凋亡小体；MTT法检测显示当作用浓度为30μmol/L~90μmol/L时，槲皮素对人结肠癌SW480细胞的生长有抑制作用，其抑制作用随着作用浓度的增加和作用时间的延长而增强；流式细胞学发现槲皮素主要作用于人结肠癌SW480细胞周期的G1/S期，大部分细胞被阻断于S期，随药物浓度的升高和作用时间的延长，G0/G1期细胞比例逐渐增加，S期细胞比例逐渐减少；酶谱分析法检测显示不同浓度的槲皮素能够抑制人结肠癌SW480细胞分泌MMP-2及MMP-9，随浓度的升高，MMP-2及MMP-9的分泌量减少；免疫组织化学法显示不同浓度的槲皮素处理人结肠癌SW480细胞后，Cathepsin-D的表达随药物浓度的升高和作用时间的延长而降低。

Paraffin slides observation found that the microspore of the RNMS line failed to vacuolate after its morphogenesis, disassembled and disappeared at last. After microspore morphogenesis, the breaking down of tapetum cells was delayed until microspore breading down.

石蜡切片细胞学观察，发现该隐性核不育能形成正常的四分体孢子，四分体释放出小孢子后，在单核花粉进入液泡化时小孢子的发育异常，不进行正常的液泡化，逐渐开始解体和消失；相应的绒毡层在小孢子形成后的降解延迟，绒毡层细胞的体积略有增大，在小孢子降解快结束时也很快解体。

Long-term aerobic exercise can effectively prevent hepatocyte number from decreasing accompanying with aging. Among the groups of aged, results showed that rats of 1-hour and 2hours group whose recovery function of hepatocyte apoptosis were of most significant. The increasing number of hepatocyte might be one of the cytological mechanisms of how aerobic exercise delays cell aging. Further researches on the phenomenon of the anomalous change of the hepatocyte apoptosis ratio among the youth groups are needed expectably.

肝细胞凋亡存在随增龄明显下降的趋势，这对维持肝细胞数量或缓解增龄过程中肝细胞数目丢失具有十分重要的意义；长期有氧运动可以有效的阻止肝细胞凋亡率在增龄过程中下降的趋势；在老年前期组中，训练1小时和2小时组对肝细胞凋亡能力的恢复作用最明显；有氧运动促进肝细胞凋亡能力的提高可能就是有氧运动延缓细胞增龄发生和发展的重要细胞学机制之一。

BACKGROUND: Neural stem cells are a kind of special cells possessing self-renewal and multi-directional differentiation potential. They are ideal carriers for studying the occurence, development and development rule of nervous system and their inherent regulation mechanism of molecular biol ogy and cytology. They have wide applicative prospect in the treatment of nervous system disease and injury.

背景：神经干细胞是一类具有自我更新和多向分化潜能的特殊细胞，是研究神经系统的发生、发育、发展规律及其内在的分子生物学、细胞学调控机制的理想载体，在神经系统疾病及损伤的治疗中具有广阔的应用前景。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。