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Amongst the many important functions of the RPE, it has the ability to phagocytosis and digest the rod outer segments which is shed on a daily basis. The malfunction of RPE leads to retinal diseases, such as retinitis pigmentosa, Best"s disease, Stargardt"s disease,Lebers congenital amaurosis and age-related macular degeneration.

RPE能吞噬脱落的视细胞外节膜盘(rod outer segment,ROS),这对视细胞外节的更新及维持正常视觉功能至关重要,其功能障碍会导致严重视网膜疾病和一些严重的遗传性变性眼病,如Best病,Stargardt病和Leber先天性黑矇,年龄相关性黄斑变性(age-related macular degeneration,AMD)等。

Amongst the many important functions of the RPE, it has the ability to phagocytosis and digest the rod outer segments which is shed on a daily basis. The malfunction of RPE leads to retinal diseases, such as retinitis pigmentosa, Best\'s disease, Stargardt\'s disease,Leber\'s congenital amaurosis and age-related macular degeneration.

RPE能吞噬脱落的视细胞外节膜盘(rod outer segment,ROS),这对视细胞外节的更新及维持正常视觉功能至关重要,其功能障碍会导致严重视网膜疾病和一些严重的遗传性变性眼病,如Best病,Stargardt病和Leber先天性黑矇,年龄相关性黄斑变性(age-related macular degeneration,AMD)等。

Mol·L~(-1) individually and also with both heavy metals present. Plasmolysis, concentrated cytoplasm, disappear ance of the cristae of mitochondria, ambiguity of framework and destruction of mitochondria envelope were all symptoms of root cells under Cu stress; hollowing cells was also found in Cd treatment, and there existed some different granule in these hollowing cells.

铜使根细胞产生质壁分离、细胞质浓缩、部分细胞空泡化,使线粒体脊突消失、结构模糊、外膜破坏;镉使根细胞空泡化,并在部分空泡化的细胞里产生大小不等的颗粒状物;铜、镉交互污染使根细胞受害程度加深,并兼有两者的受害症状特征:线粒体结构彻底破坏、空泡化细胞里的颗粒物更大电子密度更高、质壁分离现象更普遍、质膜上的颗粒物沉淀更大。

METHODS: T-lymphocyte subsets and NK activity were determined by flow cytometry in 78 patients with hypopharyngeal squamous cell carcinoma. Blood samples of 20 non-tumor patients were used as control.

用流式细胞仪对78例喉咽鳞癌患者的外周血进行T淋巴细胞亚群及NK细胞活性的检测,并取20例非肿瘤患者的外周血作为对照组。

When they are released into the extracellular environment, or when they are membrane-bound and in contact with the pericellular zone, these enzymes degrade a broad range of connective tissue proteins and are important during the development of healthy tissue as well as in remodeling damaged tissue.

当它们被释放入细胞外环境,或者是与膜结合后与细胞外环境保持接触时,这些酶能够使大范围面积的结缔组织蛋白酶降级,这样对健康组织的发育以及对受损组织的重塑相当重要。

As one of the latest detecting approaches, enrichment of exfoliated cells by immunobeads is of high efficiency and tumor specificity.

作为最新型的脱落细胞检测法-免疫磁珠富集粪便脱落细胞检测法除具有一般脱落细胞检测法的优点外,还具有细胞回收效率高、肿瘤细胞特异性高等优点。

Much progress has been made in recent years through studying septic shock,however brain injury is rarely involved.This study takes the models of endotoxin-shock rats as research object to simulate septic shock.The study aims are to explore anomalous signal transduction in brain injury caused by septic shock and the effect of Sini Decoction in the process;define the molecular and cellular mechanisms of reviving yang for resuscitation method used to prevent and treat brain injury in septic shock and establish the scientific foundation for modernizing traditional Chinese medicine.

研究目的:1。明确内毒素休克后脑损伤组织中炎症介质水平,中性粒细胞和脑血管内皮细胞等细胞表面黏附分子表达情况,脑血管平滑肌细胞、神经胶质细胞和神经细胞对细胞外炎症介质刺激产生的功能代谢变化以及结构改变等三者之间的规律性关系。2。

Objective To investigate the dose-effect effects of th ree relating bone growth factors, dexamethasone, recombinant human basic fibro blastic growth factor and recombinant human bone morphogenetic protein- 2 (rhBMP-2), on proliferation and differentiation of periosteal cells so as to provide experimental basis for their further application in bone tissue engineer ing.

骨膜细胞是骨修复、重建过程中重要的功能细胞,在一定条件下具备向成骨细胞分化,分泌骨细胞外基质的潜能,因此成为骨组织工程研究中构建细胞-材料复合体非常重要的种子细胞。

Two days after bone marrow MSCs compounded to nano-CS/COL scaffold, bone marrow MSCs presented globular shape and were scattered; Four days later, bone marrow MSCs presented shuttle shape, extended and anchored on the surface of nano-CS/COL by pseudopods; Eight days later, bone marrow MSCs proliferated and fused each other, and they secreted a lot of extracellular matrix, then which covered most material particles.

骨髓基质干细胞复合到纳米壳聚糖-胶原纤维支架后2 d,细胞呈球形散在分布;4 d 后细胞呈梭形,延展爬行且有伪足与材料表面锚靠;8 d 时细胞增殖,相互间融合,并有大量的细胞外基质分泌,大部分材料颗粒被覆盖。

AIF ex- pression in ischemia region of cortex of parietal lobe and nerve cell apoptosis degree in sham operation group, MCAO 90 min and reperfusion 0, 3, 6, 12, 24, 48 and 72 h were observed by TUNEL and immunohistochemistry technique.

除缺血90min凋亡细胞数量与假手术组比较无统计学意义外,其余各指标与假手术组相比均有统计学意义(P〈0.01),除6与12h以及24与48hAIF含量的差异无统计学意义,24与48h凋亡细胞数量的差异无统计学意义外,其余各组间差异均有统计学意义(P〈0.05)。

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