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One view is that the nucleocapsids get tegument in the nucleus, and by budding into perinuclear space, they obtain their envelope from the inner lamella of the nuclear membra...

一种意见认为,核衣壳在细胞核内获得被膜,并通过出芽在内层核膜处获得其囊膜后,进入核周间隙,进一步经与核周间隙相连接的内质网,以囊泡转运的方式经高尔基体到达细胞膜,囊泡膜与细胞膜融合,病毒颗粒释放到细胞外。

The staining of F-actin in the ischemia reperfusion group was decreased significantly (P.05) compared with the normal control group. There was a marked loss of canalicular microvilli and distension of canalicular lumen in the ischemia reperfusion group. The staining of F-actin in the LA group was significantly increased than those in the I/R group (P.05). Conclusions: Ischemia reperfusion induces an disruption of bile canalicular F-actin microfilaments and a loss of microvilli. Alpha-lipoic acid can protect bile canalicular F-actin microfilaments against IRI.

肝脏I/R可造成胆小管F-actin微丝破坏、微绒毛丧失,导致胆小管收缩减弱,胆汁排泄功能受损,这可能是大鼠肝脏I/ R后缺血型胆道病变发生的主要机制;α-硫辛酸通过清除氧自由基,降低脂质过氧化反应,调节细胞内氧化剂-抗氧化剂的含量,保护胆小管F-actin微丝结构免遭缺血再灌注损伤破坏,进而预防和治疗缺血型胆道病变。

Lysyl oxidase catalyses the cross-linking of fibrillar molecule of type I collagen into mature insoluble extracellular matrix.

离胺基氧化酶会催化胶原蛋白共价交联的过程以形成成熟不可溶的细胞外间质成份。

The first -order rate constants for the transmembrane transport of the complxes into human erythrocytes were detemined and the mechanism was studied on the basis of the interactions of these complexes with cellular membranes and liposome by ESR,fluorescence technique, mercapto measurement and gelchromatography.

测定了它们跨人红细胞膜的一级反应动力学常数。用膜蛋白巯基滴定、荧光标记、自旋标记ESR谱等方法研究了它们与膜蛋白、膜脂的相互作用;用脂质体模拟了这些配合物的细胞摄入。

Finally, we established rat model of PF induced by bleomycetin, and observed the interventional action of phenol total base to model. The analysis of experimental result including pathematologic and tissue biochemical indicator showed phenol total base of plumula nelumbinis have some therapeutic action to rat model of PF induced by BLM.

通过病理学观测及组织生化指标的检测(SOD、MAD、GSH一PX、Hyp),说明莲子心酚性总碱对博莱霉素致大鼠肺纤维化有一定治疗作用,可能的作用机制:降低肺纤维时胶原含量;抑制肺成纤维细胞的增殖;抗自由基和抗脂质过氧化作用及提高了机体内GSH一Px含量。

It is concluded that acute cadmium toxication would cause lipid peroxidation and excessive free radical production,and inhibit the activities of antioxidases leading to severe injury of hepatocytes.

镉可引起肝脏脂质过氧化及自由基的大量产生,抑制抗氧化酶的活力,造成细胞的严重损伤。

In this study we constructed the recombinant pcDNA-HA-rpb in E.coli cells and we expressed the three polymerase II subunits; Rpb5, Rpb6 and Rpb7 as HA-tagged polypeptides by transfection in 293T mammalian cells, as well as untagged nuclearβ-actin.

在这项研究中,我们在大肠杆菌中构建了pcDNA-HA-rpb重组质粒,表达三个聚合酶II亚基: Rpb5 , Rpb6和Rpb7,通过转染哺乳动物细胞293T,从而表达带HA标签的多肽,同时转染不带标签的β-actin。

Cisternae A flattened membrane-bounded sac of the endoplasmic reticulum or the Golgi apparatus, being the basic structural unit of these organelles.

潴泡:在内质网或高尔基体中存在的扁平的膜状囊泡,是这些细胞器的基本结构单位。

The principles for treatment of IC are based on (1) controlling the dysfunctional epithelium by continual replenishment of the glycosaminoglycan layer,(2) inhibiting neurological hyperactivity by administration of amitriptyline or imipramine,(3) suppression of allergies with antihistamines, and (4) pain control with non-steroid anti-inflammatory drugs, Cox-2 inhibitors or tranquilizers.

基於这些可能的生成原因,对於间质性膀胱炎治疗的原则,主要是根据:一、控制功能异常之尿路上皮细胞,补充膀胱表皮之GAG层,二、经由amitriptxline或imipramine以抑制神经性活化作用,三、利用抗组织胺抑制过敏反应,四、使用NSAID、Cox-2抑制剂或是镇定剂作为疼痛控制。

The results indicated that the well-resolved and reproducible 2-DE pattern of Golgi apparatus isolated from gastric cancer cells was obtained , and twelve proteins were identified, including proteins related to protein synthesis and folding, membrane fusion proteins, regulatory proteins, transportation proteins, proteins related to apoptosis, proteins related to cell proliferation.

结果显示分离出的纯度较高的高尔基体建立了分辨率和重复性均较好的双向电泳图谱,运用质谱技术鉴定出12个蛋白质,包括蛋白合成相关蛋白,膜融合蛋白,调节蛋白,凋亡相关蛋白,运输蛋白,细胞增殖分化相关蛋白。

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As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸,那乌黑、忧郁的眼睛,她便会相信,他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失

But because of its youthful corporate culture—most people are hustled out of the door in their mid-40s—it had no one to send.

但是因为该公司年轻的企业文化——大多数员工在40来岁的时候都被请出公司——一时间没有好的人选。