细胞基质的

Genesis,development and metabasis of solid tumor have close relationship with tumor vessel angiogenesis; extracellular matrix degradation is the key point for tumorous infiltration and metabasis;the significant biology characteristic of tumor cell is the disorder of tumor cell differentiation and apoptosis.

骨巨细胞瘤血管生成是近年来研究热点，实体瘤的发生、发展及转移与肿瘤的血管生成密切相关；细胞外基质降解在肿瘤的浸润和转移中起到关键作用；肿瘤细胞的分化凋亡障碍与无限增殖能力是肿瘤细胞的重要生物学特征。

Results The mutation mouse model was established successfully, and inflammatory reaction such as bacterial infection、inflammatory cell infiltration、proliferation of fibroblast and neogenesis capillaries of neonatal mouse model can be observed with TEM in different stage.

结果 成功建立小鼠模型；在模型小鼠出生后的不同时段中，电镜下小鼠角膜基质内可见有细菌感染、炎症细胞浸润、成纤维细胞及新生毛细血管增生等炎症改变。

The cells infected and noninfected were combined with PLGA at a concentration of 5×106cells/ml to construct tissueengineered bones respectively.They were further implanted into 8 rabbits subcutaneously using PLGA as blank control(8 implants per group). Six weeks after surgery, the implants were evaluated with histological staining and computerized analysis of new bone formation.

方法］PLGA与腺病毒Ad-BMP-7感染后的兔MSCs共培养，电镜观察了解细胞在PLGA上黏附、生长和合成分泌骨基质成分的情况；将转染基因的细胞和未转染基因的细胞分别与PLGA支架复合，构建组织工程化骨并植入体内，通过组织观察新骨形成情况。

On magnification, all tumors have sharp peripheral circumscription and all tumors were confined to the upper dermis,and tumor continuity with the epidermis was noted in some cases.Some basloid aggregations associated with a palisaded alignment of the cells at the periphery of the aggregations can be seen..

镜下可见肿瘤边界清楚，大多位于真皮浅层，部分与表皮相连，可见多数基底样细胞集合，周边细胞核成栅栏样排列，绕以明显的纤维性基质以及纤维母细胞，有时在结缔组织之间可见裂隙。

Objective To observe the effects of piperazine ferulate on synthesis of extracellular matrix and expression of connective tissue growth factor in transforming growth factor-betal (TGF-β1) induced rat glomerular mesangial cells, and to investigate its mechanism on the prevention of glomerulosclerosis.

目的 探讨阿魏酸哌嗪对转化生长因子－β1(TGF-β1)诱导下肾小球系膜细胞结缔组织生长因子及细胞外基质成分表达的影响及其意义。

Weeks after MSC implantation, Scar area index (scar length to left ventricular circumferences of the endocardium and epicardium) and the scar thickness is measured by computer-assistant planimetry as character of myocardial remodeling.

将自体骨髓基质细胞植入大鼠心肌梗死区，8周后通过图象分析仪测定疤痕指数，梗死区厚度和边缘区心肌细胞直径以了解移植MSC对左室重构的影响。

Objective: To assess the effect of marrow stroma cell transplantation on constitution hydroxyproline of myocardial infarction in rabbit.

目的：评价骨髓基质细胞移植对组织羟脯氨酸含量的影响，探讨细胞移植对心肌梗塞后心室重塑机制。

Results The expression level of ERβ was moderate or highter in stroma cell, anterior pigment epithelium as well as pasterior pigment epithelium of the iris, unpigmented epithelium, pigmented ciliary epithelium and vascular endocemet of the choroid layers.

结果 ERβ在虹膜基质细胞、虹膜前后两层色素上皮细胞、睫状体非色素上皮和色素上皮、脉络膜各层血管内皮的表达水平主要呈中表达或高表达；ERα则表达不明显。

We review the effect of rare earth ions on bone metabolism as the following three aspects:(1) effect of rare earth ions on differentiation and function expression of osteoblasts and osteoclasts;(2) effect of rare earth ions on the osteogenic and adipogenic differentiation of bone marrow stromal cells;(3) effect of rare earth ions on bone mineral phase of animals.

本文回顾了稀土离子对骨代谢影响的研究进展，探讨了其药用和安全性问题，主要从以下三个方面进行综述：(1)稀土离子对成骨细胞和破骨细胞的分化和功能表达的影响；(2)稀土离子对骨髓基质细胞成骨分化和成脂分化的影响；(3)稀土离子对动物骨矿物相的影响。

Objective To test the hypothesis that chondrocytes can promote in vivo chondrogenic differentiation and chondrogenesis of BMSCs at non-chondrogensis site.

目的探讨软骨细胞在体内非软骨形成部位促进骨髓基质细胞向软骨分化并形成软骨的可行性。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。