细胞基质的

OBJECTIVE: To find the difference of gene sequence between human and porcine ECM and to identify the ECM immunogenicity based on bioinformatics.

目的：通过生物信息学的方法找到人与猪细胞外基质蛋白的基因序列差异，并制备抗体验证基质的免疫原性。

According to the specialty of the structure,it may be predicted that the function of Kail gene come down to cell-cell adherence and cell-matrix connection.

结构分析提示它在细胞与细胞间粘附、细胞与基质的连接中可能起有一定作用，研究也证实它可以增强肿瘤细胞之间的聚集能力，降低其吞噬能力及侵袭能力，而不影响细胞的增殖力。

The matrix metalloproteinases are a group of zinc-dependent endopeptidase with homogenous structure and function; it can degrade various components of the extracellular matrix.

基质金属蛋白酶是结构和功能同源的一组锌离子依赖的内肽酶家族，能降解细胞外基质的多种成分。

The possible mechanism of phycocyanin in the proliferation inhibition of K562 cells is to increase the expression of FAK gene. The phcocyanin may be considered as a potential agent for inhibition of cancer cell proliferation.

藻蓝蛋白可能通过增强细胞基质与K562细胞表面的整合蛋白β1结合，上调K562细胞内FAK基因表达水平，恢复整合蛋白β1介导的细胞增殖抑制信号而发挥抑制K562细胞增殖的作用。

Coculture of autogenic BMSCs with chondrocytes can promote the proliferation of chondrocytes and the production of chondral matrix. Cocultured cells for seeding can save a number of chondrocytes, shorten culture periods and reduce subculture times.

自体BMSCs与软骨细胞共培养，BMSCs能增强软骨细胞的增殖，促进软骨细胞基质合成，缩短软骨细胞培养时间和减少传代次数，可节省大量的软骨细胞，与DBM复合后能有效修复关节软骨缺损。

The human bile duct carcinoma cell line QBC_(939) was neurotropic. The co-culture model of DRG/nerve cell and carcinoma cells could simulate the process of the tumor cell going through the matrix and invading the nerve fiber.

结论DRG/神经细胞-肿瘤细胞共培养模型较好的模拟了肿瘤细胞穿过细胞基质，浸润神经纤维的过程，人胆管癌细胞QBC939细胞对神经纤维具有亲嗜性。

Simvastatin may suppress interstitial fibrosis by effect CTGF、suppress cell proliferation、redue extracellular matrix accumulation.

辛伐他汀可以抑制CTGF、抑制肾小管上皮细胞的转分化、减轻细胞外基质的积聚，从而减轻间质纤维化，发挥肾保护作用。

The protection groups in the copolymers which were prepared previously could be removed and the -NH2 and -OH groups could be reconverted. These high active groups can be used to introduce more bioactive groups and molecules so as to simulate the natural environments of ECM, so the biocompatibilities and cells adhesive capabilities between scaffolds and cells could be improved remarkably.

通过脱除共聚物糖基上的保护基团，还原出-OH、-NH_2，这些高活性的基团为进一步引入具有生物活性的功能基团，实现了对细胞外基质的人工模拟，从而调控材料的细胞识别特性，增强材料生物相容性和改善细胞与材料的黏附特性。

The capacity of endothelial cells to recognize and migrate in response to the extracellular matrix depends on one or more members of the integrin family of cell adhesion receptors.

血管新生的过程依赖于参与血管生成的细胞因子和细胞粘附的协同作用，整合素是一组细胞表面受体，介导细胞-细胞间、细胞-基质间的相互作用，对内皮细胞的粘附、迁移、增殖起重要作用。

Objective To investigate the dose-effect effects of th ree relating bone growth factors, dexamethasone, recombinant human basic fibro blastic growth factor and recombinant human bone morphogenetic protein- 2 (rhBMP-2), on proliferation and differentiation of periosteal cells so as to provide experimental basis for their further application in bone tissue engineer ing.

骨膜细胞是骨修复、重建过程中重要的功能细胞，在一定条件下具备向成骨细胞分化，分泌骨细胞外基质的潜能，因此成为骨组织工程研究中构建细胞-材料复合体非常重要的种子细胞。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失