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Result: Rhesus BMSC can be got in mass by density gradient centrifugation.; Rhesus BMSC can adhere to PLGA fiber quickly after plant and its growth , division ,proliferration is good; Some cells arrange like rosary on PLGA fiber surface, some cells still form the catenate or flaky cell bridge joined among PLGA fiber.

结果:采用密度梯度离心的方法可得到大量增殖能力强的猕猴骨髓基质干细胞;接种后的骨髓基质干细胞很快粘附于PLGA纤维上,生长、分裂、增殖良好,在PLGA纤维表面形成串珠样排列,部分细胞还形成连接在PLGA纤维间的链状或片状细胞桥。

He type of ossein in group B was mainly type Ⅰ collagen while that in group A type Ⅱ and it exhibited as a process of fiber formation in group C. The reason for why TGF-β〓 can promote ossification induced by BMP is that can promote the differentiation and proliferation of mesenchymal cells to supply more target cells for BMP, promote the differentiation and proliferation of mature osteocytes and chondrocytes, inhibit metalloproteinase to decrease the destruction of bone tissue and promote calcification of bone matrix.

GF-〓能促进BMP骨诱导作用主要因其能促进间充质细胞的分裂增殖为BMP提供丰富的靶细胞、促进成熟骨及软骨细胞的分裂增殖、促进骨细胞产生Ⅰ型胶原而抑制软骨细胞产生Ⅱ型胶原,抑制金属蛋白酶的活性以减少组织破坏、促进基质钙化等作用而使骨生成能力增加,提示它和BMP具有协同作用。

During the process of osteophyte formation mesenchymal cells covering the periosteal bone surface proliferate and differentiate into chondroblasts and osteoblasts, which build up cartilage and bone matrix.

在骨赘形成过程中,覆盖骨膜骨的间充质细胞增生、分化为软骨母细胞和成骨细胞,后两者构建了软骨和骨基质。

CD34 hematopoietic stem/progenitor cells reside in the bone marrow in close proximity to the endosteal bone surface, surrounded by osteoblasts, stromal cells, and various extracellular matrix molecules. We used a bioartificial matrix of fibrillar collagen I, the major matrix component of bone, as a scaffold for ex vivo expansion of HSCs.

CD34 的造血干细胞/祖细胞存在于接近骨内膜表面的骨髓中,由成骨细胞、间充质细胞以及各种细胞外基质分子所包绕,我们采用生物人工合成的纤维胶原I

CD34+ hematopoietic stem/progenitor cells reside in the bone marrow in close proximity to the endosteal bone surface, surrounded by osteoblasts, stromal cells, and arious extracellular matrix molecules. We used a bioartificial matrix of fibrillar collagen I, the major matrix component of bone, as a scaffold for ex io expansion of HSCs.

CD34+的造血干细胞/祖细胞存在于接近骨内膜表面的骨髓中,由成骨细胞、间充质细胞以及各种细胞外基质分子所包绕,我们采用生物人工合成的纤维胶原I

Simvastatin leads to the high expression of cbfa1 in bone marrow stromal cells and increased ALP activity, which may be parts of the mechanisms underlying the anabolic osteogenetic effect of simvastatin.

本研究采用体内给药然后体外对骨髓基质细胞培养诱导的方法,旨在观察辛伐他汀对骨髓基质细胞成骨分化的影响,以探讨其促进骨形成,治疗骨质疏松的机制。

This pattern is characterized by the combination of pro-MMP-2 and membrane type 1 (MT1)-MMP expression, which drie pericellular generation of actie MMP-2 and local degradation of normal lier matrix. In addition there is a marked increase in expression of TIMP-1 leading to a more global inhibition of degradation of fibrillar lier collagens by interstitial collagenases (MMP-1/MMP-13). These pathways play a significant role in the progression of lier fibrosis.

其降解肝正常基质,同时抑制引起肝纤维化的纤维胶原降解,这种情况的特点是前明胶酶A合成和膜型1-MMP表达,使得小叶内细胞激活MMP-2和降解当处的正常肝基质,此外血浆1型组织基质金属蛋白酶抑制剂(TIMP-1)明显升高引起广泛的抑制间隙胶原酶(MMP-1/MMP-13)对纤维肝脏胶原的降解。

Matrix metalloproteinases, a gene family of Zinc-containing endopeptidase, degrade extracellular matrix and play an essential role in the metastasis process.

基质金属蛋白酶是一类Zn~(2+)依赖的与细胞外基质降解有关的基质金属蛋白酶,在肿瘤的侵润和转移中起重要的作用。

BACKGROUND: Bone marrow stromal cell transplantation in the ventricle and corpus striatum improves the symptoms of Parkinson's disease rat models and increases dopamine levels in the brain.

背景:研究证实脑室内、纹状体内移植骨髓基质细胞,能够改善帕金森病模型大鼠的症状,并增加脑内多巴胺的水平,目前仅有骨髓基质细胞治疗帕金森叠加综合征的个例报道。

BACKGROUND: Bone marrow stromal cell transplantation in the ventricle and corpus striatum improves the symptoms of Parkinson's disease rat models and increases dopamine levels in the brain. There are case reports of bone marrow stromal cells for treating Parkinson's plus syndrome.

背景:研究证实脑室内、纹状体内移植骨髓基质细胞,能够改善帕金森病模型大鼠的症状,并增加脑内多巴胺的水平,目前仅有骨髓基质细胞治疗帕金森叠加综合征的个例报道。

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However, as the name(read-only memory)implies, CD disks cannot be written onorchanged in any way.

然而,正如其名字所指出的那样,CD盘不能写,也不能用任何方式改变其内容。

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