细胞坏死

Results: Large amounts of oval cells appeared in the periportal regions in the forth week of cancer induction. These cells were OV-6 positive.

结果：诱癌4w，大鼠肝门管区及坏死区内均见大量卵圆细胞，这些细胞呈OV-6染色阳性。

Hepatocyte denaturation, necrosis and plasmocyte infiltration were demonstrated in all of the 19 patients received liver biopsy, and fibrosis was found in 17 cases and bile duct injury in 1 case.

肝活检19例，均可见不同形式的肝细胞变性，坏死和浆细胞浸润， 17例患者存在不同程度的纤维增生， 1例有胆管轻度破坏。

RESULTS: The extract of Aml could reduce the abnormally high levels of ALT and AST. Examined by light microscope , the degeneration and necrosis level of hepatocytes and the distribution of collagen fibrosis were markedly increased in the model group. The pathological changes and the c ollagen fibrosis associated with hepatic fibrosis decreased significantly in the prophylactically treated groups.

结果： 蓍草提取物预防给药能降低 CCl 4所致大鼠血清中异常增高的 ALT 、 AST 含量，光镜下观察肝纤维化模型组大鼠肝细胞严重变性、坏死，胶原纤维明显增加，蓍草预防各组大鼠肝细胞病理损伤得到明显改善。

The pathologic changes of fungal diseases in alimentary canal were tissue necrosis, ulcer formation and pseudomembranous inflammation.

其病变为消化道组织坏死、溃疡形成及假膜性炎症；炎细胞浸润不明显，且以单核细胞浸润为主；假膜性炎中有较多的中性粒细胞渗出，可能与某些细菌的混合感染有关系。

Methods: A brain concussion was produced in rats using a simple pendulum device model. One control (n=12) and six experimental groups were used(n=12 in each group). The cerebral concussion groups were assigned to sacrifice times ranging from 1 day to 24days after injury.A Morris Water Maze memory paradigm was used to assess learning and memory function. Pycnosis degeneration or necrosis neurons in the locus cerebral cortex, dorsal hippocampus, dentate fornix and brainstem reticular formation were observed and counted after brain concussion. Cholinergic neurons in the basal forebrain and brainstem reticular formation were identified and quantitated using choline acetyltransferase.

应用自制单摆式闭合性机械打击装置建立脑震荡大鼠模型；成年SD大鼠随机分为1个对照组(n=12)和6个脑震荡组(即伤后1、2、4、8、16、24d，n=12)；应用Morris水迷宫(Morris Water Maze，MWM)实验评价大鼠的学习记忆功能；用光镜对大鼠的上述脑区的固缩变性坏死细胞进行观察和计数；用免疫组化方法检测基底前脑和脑干网状结构的胆碱乙酰转移酶(cholin acetyltransferase，ChAT)阳性细胞的表达。

After HIFU irradiation, the histopathological changes of lesions of liver and kidney mainly characterized as completely coagulative necrosis, cell debris, pyknotic nuclei.

HIFU损伤后，肝脏和肾脏治疗区的组织病理变化主要表现为细胞的完全性坏死，细胞结构完全破坏，胞浆均质状，细胞核变形、碎裂、固缩、溶解。

Electron micrograph showed us that hepatocytes were damaged seriously along with the prolonged NHBD time in A group. At the NHBD 120 and 150min in A group, hepatocytes showed numerous cytoplasmic vacuoles and lysosomes, round swollen mitochondria with clear matrix and rough endoplasmic reticula which was not in a stacked arrangement.

电镜发现，A组随着心跳停搏时间的延长，肝细胞的损伤逐渐加重，至120和150min时，肝细胞内可出现大量空泡和溶酶体，线粒体和粗面内质网结构也遭到破坏，但未出现明显的坏死和凋亡改变。

The expression changes of TNF-α and p65 mRNA expression were detected by reverse transcription-polymerase chain reaction, the TNF-α level in the supernatant was determined by ELISA, and the expression of p65 in AR42J cell lines was detected by Stept Avidin-Biotio Complex.

逆转录－多聚酶链反应半定量法观察肿瘤坏死因子/p65亚单位mRNA表达的变化；ELISA法检测TNF-α在细胞上清中质量浓度的变化；链酶亲和素－生物素－过氧化物酶复合物法检测p65蛋白在AR42J细胞中的表达。

Acute diffuse lung injury were identified in toxication control group, intra-pul

结果 中毒组大鼠肺的病理学改变为急性弥漫性肺损伤，表现为肺泡腔内出血、渗出、炎性细胞浸润，肺泡隔炎性细胞浸润及纤维组织增生，⌒秃廷⑿蜕掀は赴坏死脱落。

Materials and Methods The triphasic dynamic enhanced CT findings of 52 patients with renal cell carcinoma were reviewed.

资料与方法回顾性分析52例肾癌患者的三期动态CT扫描资料，对经手术病理证实的透明细胞癌、乳头状癌、嫌色细胞癌3种肾癌亚型图像进行双盲法对比分析，比较肿瘤的大小、强化程度与模式（均匀、不均匀及主要周边强化）、有无钙化、出血、坏死与囊变、肿瘤扩散及淋巴结转移等情况，同时结合患者的性别和年龄，分析3种亚型肾癌之间的影像学差异。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。