细胞坏死

Combined with the data of cell density by hemocytometer counting or MTT staining, the equations that account for the dependence of apoptotic/necrotic percentages on the fluorescence intensities of YP/PI were derived.

结合细胞密度的计数结果(细胞计数板、MTT比色法等)，建立了用YP、PI荧光强度值计算细胞凋亡和坏死百分数的方法。

Karyokinesis could be found in the outer part and necrosis could be found in the center of the clusters occasionally.

中央则有少量坏死细胞存在，有时可见到固缩的细胞被邻近细胞吞噬。

In contract, the tumor tissue of control group kept morphology, tumor nodules composed of undifferentiated carcinoma, and some karyokinesis could be seen, some spotty necrosis were found occasionally in where the structure among tumor cells were loose associated very slight inflammatory response; At the 21 days after injected AdCMVIL-12, the tumor boundary of AdCMVIL-12-Ⅰ group were clear and felt hard by touch, section showed grey.

同期的对照组绝大多数肿瘤细胞形态完好，排列紧密，由大量未分化的肿瘤细胞组成并可见多个核分裂像，偶尔可见散在的点状坏死灶，瘤细胞之间结构松散，炎症反应很轻；AdCMVIL-12注射后第21天时，AdCMVIL-12-Ⅰ组的肿瘤组织经手摸感觉瘤体境界清楚、发硬，切面呈灰白色。

Results There were characteristic changes in cartilaginous tissue in OA, such as rough cartilaginous surface, irregular arrangement, decrease in number, degeneration and necrosis of chondrocyte, and cell cluster existed. The thickness and groundsubstance of cartilage in OA was thinning and uneven, and metachromatism could be seen.

结果 OA软骨组织表面粗糙不平，软骨细胞排列紊乱，数目减少，有细胞成簇现象，可见软骨细胞变性、坏死，软骨厚度变薄，基质染色不均匀，有异染性。

Results:It was found that in experimental group,retinal neurofibril were disorder,the ganglion cell,the cells in inner and outer nuclear layer presented nibble like lysis,necrosis and lose.gradually at 1,3,5 day after moc...

结果：接种后1、3、5天，对照组未见异常改变，绿脓杆菌接种组视网膜神经纤维排列紊乱、消失，神经节细胞、内核层细胞及外核层细胞从内向外呈蚕蚀样溶解或坏死脱落。

Results (1)The permillage of myocyte apoptosis in infarct area in elder patients with sudden death caused by AMI was significantly higher than that in control group(663.00‰±117.12‰ vs 34.30‰±20.68‰,P＜0 .01).However the permillage of myocyte apoptosis in 1-vessel,2-vessel,and 3 - vessel disease were 514.28±165.12‰,564.38‰±102.33‰ and 668.25‰±127. 19‰,respectiverly,significantly higher as compared to control group(All P＜ 0.01).But no significance was found among the three groups.(2)The size of DNA f ragment about 180～200 bp was found only in those patients with two and three ve ssels involoved.(3)The electron microscope showed the characteristics of myocyte apoptosis episodes,the others showed the characteristics of necrosis.

结果 TUNEL法发现，猝死者梗死区的心肌细胞凋亡千分数老年组(663.00‰±117.12‰)明显高于正常对照(34.30‰±20.68‰)(P＜0.001)；心肌细胞凋亡千分数在冠脉1支病变者(514.28‰±165.12‰)＜2支病变者(564.38‰±102.12‰)＜3支病变者(668.25‰±127.19‰)，虽然均明显高于正常对照(均P＜0.01)，但三组之间比较则无统计学上的差别(均P＞0.05)；冠脉2～3支病变者梗死区的心肌细胞DNA电泳可见相差约180～220 bp的阶梯片段；电镜发现猝死者梗死区内的心肌细胞核膜完整、染色质浓集、电子密度增加的凋亡特征，有的则出现核膜破裂、染色质溶解成碎屑的坏死现象。

The punctiform necrosis in the liver were found in two rats for high dose group. The white pulp cells in spleen were rarefactively distributed in four rats for high dose group.

病理学检查显示，高剂量组2只大鼠肝细胞可见点状坏死，4只大鼠脾脏白髓细胞疏松分布，各只雄性大鼠睾丸生精小管管腔直径增大，各层生精上皮细胞数目增多。

It's inhibitory function lies in inducing apoptosis without resulting in cell putrescence.

PDGF抗体对hRPE细胞增生的抑制作用主要是依赖于诱导细胞的凋亡，而不是促使细胞变性坏死，作用性质比较温和。

And the percents of apoptosis and necrosis increased. The morphology and microstructure of SiHa cells changed significantly after treated with 20 μmol/L β-sitosterol.

与对照组比较，20μmol/L的β-谷甾醇使SiHa细胞出现S期聚集、凋亡和坏死细胞增加，细胞形态和超微结构发生显著改变。

Histopathologic examination demostrated cystic necrosis in 6 patients, mult ilocular cysticrenal cell carcinoma in 3, and unilocular cystic renal cell carcinoma in 3 patients. 11 patients have been followed up.l patient died of the disease at 9 months. 10 patients had no evidence of disease,whose suvival periods ranged 10 months to 10 years with an average of 3.5 years.

其中肾细胞癌囊性坏死型6例，单房囊肿性肾细胞癌3例，多房囊肿性肾细胞癌3例。11例获随访，其中1例以颅骨转移为首发症状者术后9个月死于肿瘤转移；10例存活至今，存活时间10个月—10年，平均3.5年。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。