细胞坏死

CT displayed the structure of femoral head was vague. A piece of coloboma could be observed clearly on the cartilage of a femoral head. Medullary canal was almost filled with white adipose tissue. Osteoblasts and osteocytes decreased. Empty bone lacuna increased. Thrombus distributed widely in the bone tissue microcirculation.

MA组病理检查肉眼可见股骨头软骨面局部缺损，坏死面暴露，髓腔内大量脂肪组织堆积；光镜下成骨细胞、骨细胞均减少，空骨陷窝增多，微小血栓广泛分布，变形扩大的脂肪细胞挤压正常骨髓组织细胞，骨小梁变细破裂明显。

Therefore, this study would calculate and survey the following indexes as the quantitative indexes for evaluating the degrees of cell senescence in hepatic and brain tissues, including numbers of neurons and dendrites in brain tissues; numbers of normal hepatocytes, dikaryotic hepatocytes, swollen hepatocytes as well as flake necrosis.

为此，本研究将计测脑组织神经元与树突数量；正常肝细胞，双核肝细胞、肿胀肝细胞数目、肝组织小片坏死个数作为评价脑神经及肝组织细胞衰老程度的量化指标。

Transplantation of BMSCs in neonate rats at 24 hours after HIBD has the maximal long-lasting ethological improvement, which is induced by brain damage, and the mechanism may be that early transplantation with BMSCs reduces effectively neuron necrosis and apoptosis, and is helpful for the migration and differentiation of BMSCs.

新生大鼠缺氧缺血性脑损伤后24 h接受骨髓基质细胞移植可最大程度改善脑损伤所导致的远期行为学障碍，其机制可能与早期移植可有效减轻神经元的坏死、凋亡，且有利于骨髓基质细胞的迁移、分化有关。关键词：骨髓基质细胞；细胞移植；缺氧；缺血；脑；新生大鼠

There were nanobacteria in the nucleus and intracellar and extracellar endothelial cells under transmission electron microscopy after co-culture. The cell vacuolar degeneration, membrane structural necrosis, mitochondrin edema, mitochondrin vacuolar degeneration and lysosome myelinization were found in the endothelial cells.

混合培养后的内皮细胞透射电镜观察见细胞间、细胞内均有纳米细菌存在，细胞核内也可见纳米细菌，细胞空泡变，膜性结构类似坏死，部分线粒体水肿，空泡变，溶酶体呈现髓鞘图像。

The distribution of PA I-1 protein was mainly in tumor cells of high-grade astrocytomas, particularly abundant in areas of vascular proliferation and in tumor cells surrounding necr otic foci, whereas it was only weekly expressed in low-grade astrocytomas.

PAI-1蛋白主要分布在高级别星形细胞瘤的瘤细胞和内皮细胞，尤以血管增殖部位和坏死灶周围较为显著，低级别星形细胞瘤呈低表达。

On the one hand, the inflammatory cells and inflammatory mediators phagocytize necrosis cells and impaired cell debris; on the other hand, they activate muscle satellite cells (locate among the basilar membrane and sarcolemma, and in dormancy state when quite) by secreting growth factor to proliferate to form new myotube cells which develop muscle fiber, repair impaired muscle fiber and accomplish muscle regenerative process.

炎症因子在损伤部位发挥着双重作用，一方面吞噬坏死细胞和损伤的细胞碎片，另一方面通过分泌生长因子激活肌卫星细胞(安静时处于休眠状态的，位于基底膜和肌膜之间)，使其增殖形成新的肌管细胞进而发育成肌纤维，修复损伤的肌纤维，完成肌肉的再生过程。

Nevertheless, as to the antioxidant activity, HA andβ-PPA could also protect cells against oxidative stress within a relatively short duration time when compared to α-Toc. TS didn't show any effect against oxidative stress in the range of our treated doses. In the remanding experiments, all of HA,β-PPA and TS didn't show any activity in the protection of rat primary hepatocyte cells against H2O2-induced oxidative stress, and in the inhibition of telomerase.

在前骨髓白血球HL-60程式化死亡系统中，HA会诱发HL-60的程式化死亡，β-PPA和AMBL-029C-TS只会直接诱发细胞的坏死，在观测抗氧化效果方面，以对HL-60细胞不呈细胞毒性的浓度观察，得知HA和β-PPA在短时间内有保护细胞不受氧化压力的能力，但在长时间后，对抗氧化压力的效果不如α-Toc明显，AMBL-029C-TS则没有明显抗氧化压力的能力。

Two different signals, whichwere brown and blue, reacted with the substrate (DAB and NBT/BCIP) separately, could be observed in the WSSV infected haemocyte. The result showed that in the lightly infected tissues infected haemocytes predominated in all infected cells. However in the heavily infected tissues the number of normal haemocyte decreased obviously and infected cell with strong positive intensity increased, and cell debris and tissue necrosis were observed.

应用这种双重免疫组化方法观察了被WSSV感染的血细胞在几种组织中的分布情况，发现在轻度感染组织中被侵染的血细胞在所有被感染细胞中占绝大多数，而在高度感染组中血细胞数目明显减少，细胞变形，出现许多的细胞碎片，同时被病毒感染的细胞数目增多，染色强度增强，组织坏死严重。

Results Basal cell adenocarcinoma of prostate was composed of poorly differentiated solid carcinoma nests with many cellular nuclear mitoses arranged like basal cell carcinoma. Necrosis was in the middle of the carcinoma nest. Local differentiation to squamous cell, transitional cell and gland and structure like adenoid cystic carcinoma were found.

结果：前列腺基底细胞腺癌为分化差的实体癌呈基底细胞癌样排列，核分裂象多，癌巢中央伴坏死，可见局灶性鳞状细胞、移行细胞或腺管分化，也可出现腺样囊性癌样结构。

The result showed that LPS inhibited the proliferation of pulp cells when its concentration was 100μg /ml; it could induce the apotosis of the cell when in 250μg /ml and it could lead the pulp cell to die when in 450 μg/ml.

g／ml浓度的LPS可抑制细胞生长，使细胞体积缩小；200μg／ml浓度的LPS可使个别细胞收缩变圆，发生类似凋亡样改变；而400μg／ml浓度的LPS可使细胞肿大、破碎发生坏死样改变。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。