细胞发生的

Epidermal cells near the wound dedifferentiate and proliferate forming blastema and/or migrate to the wound plane forming a pre-epidermis consisting of several layers of stem cells covering the wound plane, which then re-differentiates further forming fully developed epidermis. Cells in the parietal peritoneum are also induced by injury to dedifferentiate into stem cells which then proliferate and migrate along the parietal peritoneum to the wound place forming a pre-peritoneum which re-differentiates into fully developed parietal peritoneum.

伤口愈合包括伤口闭合、顶端表皮层及体腔上皮的新生：创伤后的前4 d，残腕顶端的肌肉组织向伤口处迁移并重排使伤口闭合；创伤附近的表皮层细胞发生脱分化并增殖后迁移到创伤面形成由数层干细胞组成的前表皮层，之后进一步分化形成表皮层；而体腔上皮细胞在创伤诱导下也脱分化并增殖，然后沿体腔上皮迁移到创伤处形成"前体腔上皮"，经再分化形成新的体腔上皮。

Because the signaling molecules RAS and ERK1/2 (extracellular signal–regulated kinases 1 and 2) are activated by an LH surge in granulosa cells of preovulatory follicles, we disrupted Erk1/2 in mouse granulosa cells and provide in vivo evidence that these kinases are necessary for LH-induced oocyte resumption of meiosis, ovulation, and luteinization.

研究人员仍然在试图解析接着发生的那些导致排卵（或在某些情况下没有排卵）的分子信号级联反应。研究人员现在证明，激酶ERK1和ERK2是该激素信号的至关重要的下游标靶。在那些颗粒细胞中缺乏这些酶的雌性小鼠中，其卵母细胞不会成熟，因而不会从它们的滤泡中释放出来。

The model had a high incidence and its pathologic changes were close to those of multiple sclerosis, so it might be an ideal model for the research of MS. 2. It is supposed that the activity of T cell response to MOG_(35-55) and the increases of anti-MOG_(35-55) antibody and IFN-γlevels may play key roles in the onset of EAE.

通过比较EAE小鼠和正常小鼠T淋巴细胞的增殖、血清抗MOG_(35-55)抗体和IFN-γ水平的不同，显示T细胞的活化、抗体的升高、细胞因子的异常可能共同导致了EAE的发生。

Abstract］ AIM:To investigate the role of nuclear factor κB in the induction of iNOS gene by TNFα and LPS in endothelial cells and the effect of antioxidant on the induction of iNOS. METHODS:Nitrite was determined based on Griess reaction. iNOS mRNA was analyzed using Northern blot. NFκB in the cell nucleole was detected with electrophoretic mobility shift assay.RESULTS:(1)NO production and iNOS mRNA expression induced by LPS and TNFα was blocked by pyrrolidine dithiocarbamate or N-acetylcysteine.

研究表明内皮细胞激活时iNOS表达的调控主要发生在转录水平。iNOS基因的启动子区域含有多个转录因子的结合位点包括NFκB、AP-1、NF-IL6，Oct-1等［2］，而核因子κB(nuclear factor κB， NFκB)被认为在多种参与炎症反应的蛋白质因子的基因调控中担任重要角色，因而可能是内皮细胞激活的调控中一个重要转录激活因子［2，3］。

The adjustment mechanism of the follicular development is very complex. The influence of ovarian local factors and the influence from follicle itself were mainly discussed. During the oogenesis, many ultra microstructure changed.

卵泡发生的调节机制非常复杂，在此重点研究卵巢局部因子对卵母细胞发育的影响以及卵泡各结构间的相互影响，卵母细胞发育的过程中也出现了超微结构的改变。

Though it can improve the plant tolerance using the CaMV35Spromoter to express the related genes in stress environment, the expression of resistant proteinwastes the energy in normal environment and the accumulation of the protein can inhibit the plantsnormal metabolism, causing the morphology change of the plant, resulting in growth anddevelopment retardment of transgenic plants.

利用组成型表达启动子控制抗性相关基因的过量表达虽然可以提高植物在逆境条件下的抗逆能力，但正常环境条件下细胞内组成型过量表达抗逆蛋白则是一种能量浪费，且正常环境下细胞内的抗逆蛋白长时间过量的积累可能妨碍植物的正常生长代谢，引起植物的形态发生改变，造成转基因植物生长发育严重停滞甚。

A dose-dependent inhibition of cGMP-PDE activity was observed when cUMP 10~(-6-10~(12) M was added to the culture medium, which may explain the increase of the level of intracellular cGMP, while the activity of cAMP...

浓度为10~(-6)-10~(-12)McUMP对胞内cAMP-PDE活性几乎没有影响，而抑制cGMP-PDE的活性，抑制作用随cUMP浓度降低而减小，这可能是胞内cGMP水平增高的原因。cUMP可能与细胞的cAMP PK结合，释放催化亚单位，细胞生长的抑制可由此发生。

Result: CDK4 and P16 were expressed in parabasal layers and the upper layer, mainly in the prickle and granular layers of cholesteatoma epithelium.

CDK4与P16在中耳胆脂瘤发生中是共同而非单独起作用的，从细胞周期的角度可反映胆脂瘤上皮细胞过度增殖的同时也增强负调控因子来抑制增殖，使凋亡同时加快而达到新的平衡。

Results:According to their size, 68 cases of intramural and subserous hysteromyomas were exposed to HIFU, which had focusing property.After treatment, the total efficacy was 100%(68 cases), while cure rate and significant efficacy were 34%(23 cases) and 53%(36 cases) respectively.

利用 HIFU在人体内部的可聚焦特性，用瞬间高温致肌瘤细胞发生不可逆的变性和凝固性坏死，坏死的肌瘤细胞逐渐被周围组织吞噬、吸收，达到其&纯无创&治疗子宫肌瘤的目的。

It was also found that protein tyrosine nitration could induce cell injury further. Tyrosine nitration induced by high glucose was different from extrinsic factors. It could be speculated that protein was nitrated selectively to generate nitrotyrosine in diabetic vascular complications.

研究发现：蛋白质硝化可以进一步加强细胞损伤的程度，而高浓度的糖和外源性硝化试剂导致的细胞蛋白硝化有所不同，其原因可能是在糖尿病血管并发症中蛋白质是有选择地发生硝化反应的。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。