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Chk1 is one of the major checkpoint gene involved in G2/M checkpoint, as well as involved in G1/S and Intra S arrest. We use U937 human monoblastic leukemia cell as a model to study human Chk1 RNA isoforms and transcription regulation.

Checkpoint 的功用为侦测细胞内DNA damage的发生,并藉由阻止细胞周期的进行,提供细胞足够的时间修复错误,Chk1即为其中的一种重要的基因。

Imaging research in nude mice bearing human breast cancer exhibited that radioactivity has been accumulated in tumor site, While only slightly visualized or nonvisualized in the control group of mice.(4) Compared with the negative control group, the 〓I-EGF trial groups remarkably suppressed the growth of tumor.

〓I-EGF静脉和瘤内注射对荷瘤裸鼠有较强的肿瘤抑制作用,病理组织检查及透射电镜细胞超微结构观察发现肿瘤细胞发生一系列不可逆损害变化,而〓I或〓I-白蛋白无此作用; 6。

A development-course observation of the morphological changes in the nucellar cells undergoing PCD to form pollen chamber was performed.

在珠心细胞发生PCD的过程中,其形态变化显著,有序地降解细胞组分,其间液泡起着关键作用。

The expression of vimentin may play an important role in the invasiveness and metastasis of the RCC, and may be considered valuable in evaluating the ontogenesis and prognosis of the cancer.

vimentin可能在肾细胞癌的进展和转移过程中发挥重要作用,并可能为早期监测肾细胞癌发生及利断预后提供依据。

According to the previous results, BNIPL-2 could interact with Cdc42GAP and suppress the GAP activity of Cdc42GAP toward Cdc42. BNIPL-2 also had a BCH domain (BNIP-2 and Cdc42GAP homology), which could induce short and long pseudopodia, and subsequently was needed to trigger cell migration. So we presume BNIPL-2 could be involved in cell migration and cancer metastasis.

前期实验发现,BNIPL-2可以和Cdc42GAP发生相互作用,并且抑制Cdc42GAP的活性;而且BNIPL-2中有一个重要的结构域:BCH domain,它可以诱导细胞伪足的产生,从而参与调节细胞的运动,提示了BNIPL-2可能参与细胞的运动和肿瘤转移。

In conclusion, the mechanism of differentiation and apoptosis in NB4, K562 cells induced by tributyrin may associate with its up-regulation of acetylated histone and p21(superscript WAF1) mRNA level.

TB诱导NB4、K562细胞发生分化和凋亡的机制与TB引起细胞组蛋白高乙酰化和继而上调p21(上标 WAF1)表达有关。

The coincident decreased expression of EGFR and NM23 may play an important role in the development of trophoblastic tumors.

EGFR与NM23在恶性滋养细胞肿瘤中两者一致性减低,提示这种减低可能在滋养细胞肿瘤的发生及恶性转化中有协同作用。

Cellular immune response would occur later and would be weaker in xenogenic hepatocellular transplantation.

在异种肝细胞脾内移植中,细胞免疫发生的较迟和/或较弱。

VE-cadherin moved away from the transmigration site to different ends of it, whereas PECAM-1 opened to surround the periphery of a transmigrating PMN.

我们发现在PMN穿过内皮细胞层时,这两种连接体蛋白都不会突然消失,而是发生了渐进的相对移动--相邻内皮细胞间原本彼此接合的VE-cadherin会沿著细胞间的界线移向PMN两端;而PECAM-1的变化则是打开原本彼此间的键结,改而围绕在PMN周边。

The BTSCs attached to poly-L-lysine-coated coverslips and differentiated when the serum-supplemented medium was added.

在含血清培养基中脑肿瘤干细胞发生贴壁分化,产生具有多种细胞形态的分化细胞。

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Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气,收缩臀部肌肉;拱起身体,尽量抬起头来,右腿伸直朝向天花板(膝微屈,以避免肌肉紧张)。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化,但却比去年同期高8%。

However, to get a true quote, you will need to provide detailed personal and financial information.

然而,要让一个真正的引用,你需要提供详细的个人和财务信息。