细胞发生

ZHAO Yede*,HE Qinglian.Department of Plastic Surgery, Navy 411 Hospital, Shanghai 200081Objective To investigate the expression level and intracellular distribution of calreticulin in hypertrophic scar-derived fibroblastsand normal skin-derived fibroblasts.

增生性瘢痕(Hypertrophic scar， HS)作创伤及外科手术后常见且十分棘手的皮肤组织疾病，瘢痕组织内成纤维细胞异常活化和细胞外间质过度沉积既是HS的重要组织学特征，也是HS发生、发展的物质基础。

In this study we provide evidence that inhibition of Rho kinase activation or myosin contractility abrogates PMA-induced apoptosis, and turns cells to undergo PMA-induced differentiation program, suggesting a switching role for the RhoAJROCK/myosin contraction pathway in cell fate decision.

在我们的研究中发现抑制Rho kinase 的活性或肌动蛋白收缩将阻断凋亡的发生，而使细胞全数走向分化，证实了RhoA/RocK 活化所造成的myosin 滑动收缩的机制，对细胞因应刺激而决定其命运的过程中扮演一决定性角色。

TNF specially bound to TNF receptor on tumor cellular membrane and swallowed, which bound to lysosome and made it lysis, resulting in cell autolyzed;(3) made micro-vascular endothelial cell injured, thrombosis, resulted in tumor avascular necrosis.

TNF与肿瘤细胞膜TNF受体特异性结合并内吞，与溶酶体结合发生溶酶体破裂，导致细胞自溶；(3)引起肿瘤微血管内皮细胞损伤，血栓形成，导致肿瘤缺血性坏死。

METHODS: Rabbits were fed with either high cholesterol or standard chows for 10 weeks.

日本大耳白兔分为对照组和高胆固醇饮食组，饲养10 wk后，检测血脂水平，心电图和室颤阈值，并利用全细胞膜片钳技术记录心室肌细胞的ICa，L，组织化学技术检测动脉粥样硬化发生情况。

Essentially, if you don't have glutamine, the cell is short circuited due to a lack of glucose, which halts the growth of the tumor cell Ayer says.

基本上，如果没有谷氨酰胺，细胞生长由于没有糖类而发生短路现象，从而减缓肿瘤细胞的生长， Ayer博士说。

The important reason is that the DNA exists and cumulates for a long time. There are many DNA damage restoration system in the cell when the organism is in the long course of evolution in order to keep stability.

大肠黏膜细胞是不稳定细胞，极易受到各种各样有毒物质的刺激造成DNA损伤，若得不到及时修复，突变积累易发生恶性转化。

Apoptosis is closely related to denervated muscular atrophy. The increase of Fas gene expression and decrease of Bcl-2 gene expression play an important role in apoptosis of skeletal muscle cell.

1。失神经支配后骨骼肌的萎缩与骨骼肌细胞凋亡有关，凋亡相关基因Fas的表达增加及Bcl-2的表达减少在骨骼肌细胞凋亡的发生机制中起着重要作用。

Extracellularly recording the responses of dLGN neurons to sinusoidal gratings with different orientations showed that optimum orientations of dLGN neurons in trained cats, compared with that in untrained cats, did not shift in favour of the trained orientation. For cells with receptive fields located within 15°visual acuity away from the foveae, there are no difference in orientation bias and firing rate at trained orientation between the trained cats and untrained cats.

细胞外记录外膝体背核神经元对不同方位正弦光栅刺激的反应显示，垂直或水平方位正弦光栅信号训练的猫，与正常猫相比，其外膝体细胞的最优方位并未向着训练方位发生明显改变，对于感受野位于中央区15 度视角以内的细胞来说，其方位选择性强度以及在训练方位的发放强度与正常猫无明显差异。

The infection of EBV may transform the infected cells by immortalizing them and the expression of the virus encoded proteins LMP-1 may activiate the expression of c-myc.

一myc的表达有显著影响，提示EB感染细胞后其编码的LMP一1可促进细胞的增生和转化，经过信号传导及附加的基因突变，最终可激活并促进c一myc的高表达，导致NHL 等相关疾病的发生。

The carotenoids may prevent the carcinogenesis of BQE indued hamster oral cancer by act as suppressor inhibiting the expression of PCNA and CK14. By the way, the anti-cancer mechanism of different carotenoids may be not the same pathway.

类胡萝卜素能预防口腔癌症的发生，在细胞增殖、细胞异常化生、乳突瘤和恶性肿瘤病灶中PCNA和CK14的表现降低，而不同的类胡萝卜素之间预防癌症的机制可能不尽相同。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。