细胞发生

Thirty-seven of 38 patients with follow-up are alive without disease and 1 is alive with disease (median 59 mo follow-up duration, range: 8 to 108 mo). Six cases showed myxoid liposarcoma with spindled growth (spindle cell myxoid liposarcoma); these arose in 5 females and 1 male (median age 14 y) and involved the thigh in 40% of cases.

随访的38例都存活，其中37例无再发，1例伴病（随访中位时间为59个月，范围：8至108个月）。6例黏液样脂肪肉瘤的瘤细胞生长方式为梭形（梭形细胞黏液样脂肪肉瘤），患者为5名女性、1名男性（中位年龄14岁），40%病例的肿瘤发生于大腿。

This study demonstrates the integral function of SA, particularly streptococcal DNA, in the pathogenesis of psoriasis.

该研究通过揭示链球菌抗原的生物学功能，发现non-NASA相比SA可显著降低银屑病患者PBMC增殖和T细胞活化，提示链球菌DNA可辅助活化致病性T细胞，诱导银屑病的发生与发展。

We studied the mechanism of occurence of kindling and long-lasting maintenance of epileptic behavior in the levels of the whole, cell ular, subcell ular and molecular The conclusion from the study were shown as follows

本实验从组织、细胞、亚细胞和分子水平对点燃的发生和点燃后大鼠致痫性增高长期存在的机制进行了较系统的研究，根据上述结果小结如下

Among the earliest events in atherogenesis are the binding of monocytes to endothelium and their migration via the junctional spaces between endothelial cells till to the subendothelial spaces.

在高脂血等情况下，血液中的单核细胞不断粘附、进入动脉内膜并在内膜下聚集成为泡沫细胞是动脉粥样硬化发生发展过程中的重要环节。

These include physical characteristics, such as repulsive forces resulting from the electronegative charge of both platelet and endothelial cell membranes, and biochemical attributes, such as the synthesis and release of inhibitors of platelet activation. Platelets respond rapidly to alterations of endothelial cells and to exposure of subendothelial structures by attaching firmly to the site of the lesion.

正常情况下，循环中的血小板与血管壁内皮细胞层紧密接触但不发生黏附，是因为血管内皮细胞具有一定的活性功能，包括一些物理特性如血小板和内皮细胞膜均带有负电荷产生相互排斥作用以及生化作用如合成和释放血小板活化抑制剂。

The results are unsure for experimental use;The rabbit's corneas that were removed with upper-half of corneal limbal epithelium lamella and erased the center corneal epitheliums were transparent with intact corneal epithelium;In the approach,the corneal and limbal epitheliums were burned with a cotton swab socked in 1 mol/L NaOH,there were 4 rabbits' corneal stroma happened perforation or ulcer and symblepharon,and the other one presented corneal epithelium phenotype.This is an applicable method to create the pathological model of corneal limbal stem cell total deficiency.

结果表明，处理后4周，全周角膜缘上皮板层手术切除，中央角膜上皮层用1 mol/L NaOH擦除的5只试验家兔角膜表面全部血管化、结膜化，未发生睑球粘连，角膜基质胶原纤维完整未见溃疡、穿孔等病变，细胞印迹学检查为结膜表型，可作为实验性角膜缘干细胞移植的病理模型；全周角膜缘上皮板层手术切除，中央角膜上皮用生理盐水擦除的5只试验家兔，有2只为结膜表型，另3只为角膜表型，观察期内结果不稳定；半周角膜缘上皮板层手术切除，中央角膜上皮层用生理盐水擦除的5只试验家兔，角膜表面透明，全部为角膜表型；直接用1 mol/L NaOH擦除角膜缘和中央角膜上皮的试验家兔，有4只角膜基质胶原纤维断裂、溶解，并伴有严重的溃疡、穿孔、睑球粘连等病变，不能用于移植试验，另1只角膜表面透明，未见结膜和新生血管长入，细胞印迹学检查为角膜表型。

The results shows that the tapetal expanding abnormally occurs in dyadphase stage, microspore abortion occurs in the early of monokaryon stage, disaggregation in the end of monokaryon stage, only some spall of microspore is observed in monokaryon stage, the four cell walls also exist, the tapetal cells became completely vacuolated, almost filled the whole locule. vascular bundle of male sterile line anther vanish at mature pollen stage.

结果发现花药绒粘层在二分体时期发生异常，小孢子在单核前期开始败育，至单核后期完全解体，花药发育后期不育系药腔中只观察到少量的小孢子残体，花药壁的四层细胞依然存在，绒粘层细胞已经彻底液泡化，占据了药腔的整个空间，花粉成熟期不育系花药维管束消失。

Microscopic observation of microsporogenesis of the male sterile lines revealed that abortion occurred mononuclear stage. The tapetal cells became higly vaculate, pressing the microsporocyte seriously, interfering the normal microsporpgenesis development and finally leading to pollen grain abortion.

进一步对其细胞形态学进行观察结果表明，ogura和改良型不育系败育时期发生在单核花粉期，绒毡层异常膨大，挤压小孢子正常发育，小孢子液泡化而导致败育，并且在花药发育过程中有一些异常现象发生。

The development of HLA-peptide tetrameric complexes to directly visualize HBV specific CD8+ T cells has recently provided the opportunity to investigate the relationship between HBV-specific CDS* T cells and liver damage in more details.

Fetramer技术结合胞内因子染色和表型分子的检测，近年来使人们对CTL 的认识迅速达到单个细胞水平，并从T细胞分化的角度对慢性持续性病毒感染的发生机制有了全新的认识。

The interaction was not dependent on the tetrameric structure and enzyme activity of GNMT. Further, we identified GNMT can promote nuclear accumulation of ARRB1 in HeLa.

免疫荧光共定位实验显示，当ARRB1与GNMT共转染HeLa细胞后，ARRB1蛋白的亚细胞定位发生改变，表现出与GNMT蛋白共定位，有入核的趋势。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。