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The expressed fusion proteins come mainly into aggregation in cells and seem not to take part in the structures of S. pombe

表达的融合蛋白在细胞中发生聚集,可能未参与到酵母细胞的结构中。

The results of protein synthesis of NT embryos indicated that the protein synthesis pattern of NT embryos and fertilized eggs was similar. 19. 2 KD protein existed in 32-cell stage donor embryos disappeared in NT embryos at the pronuclear stage, however, this protein was reprogrammed to reappeared in 32-cell stage NT embryos.

七、核移植胚的蛋白合成分析结果表明,原核期核移植胚与原核期受精卵具有相同的合成模式。32-细胞期供体胚中的19.5KD蛋白在原核期重组胚中消失,而在32-细胞期重组胚中再度出现,发生了蛋白合成的重序过程。

The psammoma body mineralization in meningioma is a common type of mineralizationThe analysis of the mineral composition may provide some support information in finding the reason of happening and developing of the diseaseThis paper focuses on the concentric layered structure mineralization in meningiomas, using mineralogical methods, such as HRSEM, ESEM, EDAX, EPMA, HRTEM, XRD and FTIR to systematically investigate the mineral composition, structure and shape of the minerals in psammoma bodies in meningiomasWe have devised a method for preparing the silicon wafer sheet which was used for the ESEM insitu observations and analysisIn this study, we first got the ESEM and HRTEM images of the initial mineralization phase of meningiomasThese images showed that in the early stage of psammoma body mineralization in meningiomas, many mineralized balls composed of octocaphosphate were precipitated on the collagen fibersThese balls continued to grow and aggregate, and were gradually hydrolyzed to become the dahlliteThe continued development of mineralization resulted in the mineralized collagen fibersThe study revealed that the concentric layered structure of the psammoma bodies in meningiomas is formed by the spiral arrangement of the mineralized collagen fibers on which the mineralized grains precipitated.

砂粒体矿化是脑膜瘤中常见的矿化类型,对其形成机理和矿物成分的分析可能会对肿瘤发生、发展的研究提供辅助信息。该研究选取人脑膜瘤中的砂粒体矿化作为研究对象,采用偏光显微镜、环境扫描电镜及能谱、X射线衍射仪、高分辨透射电镜和电子探针对样品的形貌、结构和成分进行测试分析,并以此为依据探讨脑膜瘤中砂粒体的形成机理。研究结果表明矿化的初期为沉淀在胶原纤维上的矿化小球,成分为磷酸八钙;矿化小球不断生长聚集,并逐步水解为碳羟磷灰石晶体,矿化的不断发展致使胶原纤维也发生矿化。砂粒体的同心层状构造是由螺旋状排列的矿化胶原纤维及沉淀在其上的矿化颗粒组成的集合体,而不是多数研究中所述:砂粒体是以坏死细胞残骸为中心由内至外的同心层沉淀。

The fluorescence silgnal on Thr11-phorphoslated histone H3 reached the strongest at early metaphase at the centromere punctated in the central of mitotic cell.

结果显示:在MCF-7细胞中,组蛋白H3 Thr11的磷酸化发生在早前期细胞染色体的着丝粒处,成点状分布,继而在早中期达到最高水平,并眨羔状集中在赤道板上,在有丝分裂后期开始脱磷酸化,并于末期完成脱磷酸化。

The expression of AT2R gene can be regulated efficiently in vivo by local delivery of MSC with dual-stable expression of AT2R gene, thus reduces the formation of intimal hyperplasia.④AT2R gene can influence the expression of ECM and significantly promote the cellular apoptosis in the injury rat carotid artery.⑤These data demonstrate the clinical potential of AT2R regulatable expression to prevent restenosis after PCI.

研究结论:(1)与VSMC直接接触可以诱导MSC向血管成分细胞分化;(2)构建的Dox-on可调控的MSC细胞株诱导活性可靠,使外源AT2R基因的表达处于有效的主动控制下;(3)局部导入MSC不影响球囊损伤后大鼠颈动脉新生内膜增生;(4)由MSC介导的AT2R可调控表达受到Dox的良好调控,可有效抑制球囊损伤后大鼠颈动脉新生内膜增生;(5)AT2R影响血管损伤后修复时ECM成分的表达,并促进细胞凋亡的发生,可能是AT2R介导抑制新生内膜形成的机制。

Results(1) Group of electroacupuncture in Shu and dense wave can significantlyreduce the degree of ankle swelling(P<0.05, P<0.01), which shows thatelectroacupuncture has obvious anti-inflammatory and repercussive roles;(2) Theresults of HE staining showed that group of electroacupuncture in Shuand dense wave can significantly reduce inflammatory cell infiltration,inhibit synovial cell proliferation, and decrease proliferation of granulationtissue in rats joints;(3) group of electroacupuncture in dense-wave can increase the pain thresholdof experimental rats (P<0.05, P<0.01), reduce the content of peripheral painmediums, such as K~+, DA and 5-HT(P<0.05, P<0.01), which shows thatelectroacupuncture has significant analgesic effect;(4) In the local lesion of joints, electroacupuncture can significantly reducethe content of IL-1β, IL-8, TNF-a, increase IL-4 content, decrease theexpression of COX-2mRNA, and significantly promote the expression ofHSP-70 protein in synovial tissues of acute gouty arthritis rats (P<0.05,P<0.01),thus restrain the occurrence of synovial tissue inflammation.

结果:(1)电针疏密波组能显著减轻踝关节肿胀度(P<0.05,P<0.01),表明电针有明显的抗炎消肿作用;(2)HE染色显示:电针疏密波组可使大鼠关节炎症细胞浸润明显减轻,滑膜细胞增生明显被抑制,肉芽组织增生明显减少;(3)电针密波组能提高实验性大鼠痛阈(P<0.05,P<0.01),降低外周疼痛介质K~+、DA、5-HT的含量(P<0.05,P<0.01),表明电针有明显的镇痛作用;(4)在病变关节局部,电针能显著降低急性痛风性关节炎大鼠滑膜组织IL-1β、IL-8、TNF-α含量(P<0.05,P<0.01),升高IL-4的含量(P<0.05,P<0.01),并降低关节滑膜内COX-2mRNA的表达(P<0.05,P<0.01),可促使急性痛风性关节炎大鼠滑膜内HSP-70蛋白表达显著增加(P<0.05,P<0.01),从而抑止滑膜组织炎症发生。

Endoplasmic reticula in enlarged C-tapetal cells were aggregated in stacks at first, and then produced numerous ER-vesicles. As inclusions in the vesicles increased, the cytoplasm in these cells decreased until it was replaced by starch grains and lipid droplets.

膨胀的C-绒毡层细胞中,内质网先发生聚集,之后断裂并产生大量内质网小泡;随着内质网小泡内容物增浓,细胞质逐渐变稀;最后,细胞内容物几乎全部变成多糖颗粒和以脂类物质为主的滴状物。

The mcm10 gene in WJ-1 cells was not reversionally mutated and still maintained the allele in mcm10-1 cells.

序列测定表明,WJ-1细胞中mcm10基因没有发生回复突变,仍维持mcm10-1细胞中mcm10基因的突变。

The embryogenic cell first divided into multicellular proembryos,then globular embryoid,pearshaped embryoid,long embryoid,scutiform embryoid and mature embryoid.

胚性细胞继续分裂形成多细胞原胚,经球形胚、梨形胚、长形胚、子叶分化期到成熟胚,其发生的胚状体与单子叶合子胚形成具有相似的过程。

Objective To study the MRI findings and the clinical features of the juvenile pilocytic astrocytoma of sellar region.

目的 分析发生在鞍区的青少年毛细胞星形细胞瘤的MRI特点及临床发病特点。

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Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书,王祥生,李德昌。安徽省首次发现嗜群血蜱。

Chapter Three: Type classification of DE structure in Sino-Tibetan languages.

第三章汉藏语&的&字结构的类型划分。