细胞发生

CaLP's phosphorylation state analysis of different localization showed that when CaLP is overexpressed alone, it is in state of phosphorylation and stays in the cytoplasm; when CaLP is co-transfected with p21, p21 overexpression causes its unphosphorylation and translocated from cytoplasm to nucleus.

对定位于不同部位的CaLP的磷酸化状态的分析表明：当在细胞中单独表达CaLP时，它以磷酸化形式存在，且磷酸化的位点发生在Y139上，CaLP因此定位于细胞质中；当共表达CaLP与p21时，p21的过表达引起CaLP发生去磷酸化，CaLP由细胞质穿梭入细胞核并与p21发生直接相互作用。

In addition, we presume that the role of different MMPs is distinct in various stages of EMs development. The difference of subjects which is resulted by the genetic difference of MMP-1 has the association with the risk of EMs, and the abnormal expression of protein may have relation with the development of EMs; The abnormal expression of MMP-3 has a very important role in the development of EMs; As a protein of endothelial expression, MMP-7 may participate in the development of EMs, endometrial cells with high-expression MMP-7 easily take place ectopic implantation in the blood of menstruate countercurrented and increase the risk of EMs; It is not confirmed in our study that there are the association of MMP-9 with the risk of EMs, but in view of other study, we will further evaluate the role of MMP-9 in the development of EMs.

且推测不同的MMPs基因在子宫内膜异位症发生和发展的不同阶段作用不同，MMP-1基因的遗传差异所导致的个体差异与子宫内膜异位症发病风险的个体差异相关，其蛋白的异常表达还可能与子宫内膜异位症的进展相关；MMP-3基因的异常表达在子宫内膜异位症的发展中起重要作用；MMP-7作为一个上皮性表达的蛋白，可能对子宫内膜异位症的发生起重要作用，带有MMP-7高表达的在位子宫内膜细胞更易在经血逆流中"异位"种植，增加个体子宫内膜异位症的发病风险；MMP-9虽然在本研究中没有被证实与子宫内膜异位症的发生和发展有相关性，但鉴于其它相关研究，有待于从其它方法证实MMP-9在子宫内膜异位症进展中的作用。

Part Ⅱ Effects of sex hormones on action potential and I〓、I〓 current in rat ventricular myocytes Objective To investigate effects of estrogen and androgen replacement on action potential and I〓, I〓 current in rat ventricular myocytes, from which to elucidate the ion mechanism of gender difference in torsade de pointes.

雌雄大鼠发生TdP的性别差异性与性别本身无关，关键在于性激素的差异，雌激素可通过使心肌细胞在复极延长的基础上EAD发生增加，导致触发活动，从而发生TdP；雄激素的作用则相反。

The difference as regards the latency and duration between EAP and EAU seems to show that the pineal gland is more susceptible to retinal autoimmune reac- tions than retina and uvea, indicating that one mechanism or factor for"ending inflammation"presents in ocular tissue rather than in pineal glands.

特异性抗体出现于EAU发生之前，EAU发生于特异性抗体上升阶段，提示体液免疫反应在其发生中起着一定的作用，而特异性Th细胞的激活及其所产生的IL-2，则可能对EAU的发病有更为重要的作用。

The results were showed that embryogenic calli were induced from young leaves, which were cultured on MS medium supplemented with 2,4-D 2mg/L and KT 0.2mg/L. For the proliferation of embryogenic calli, the suitable culture medium was MS+BA 8mg/L +NAA 1mg/L. The development and maturation of somatic embryo could be much improved by using the medium of MS+ZT 2mg/L or BA 5mg/L +IAA 0.2mg/L. For the induction of secondary somatic embryo from integral somatic embryo, the suitable culture medium was MS+KT 0.1mg/L+NAA 0.01 mg/L or MS+ZT 0.1mg/L+NAA 0.01 mg/L, the proliferation frequency is 214%, 256% respectively. The cotyledonary generated from somatic embryos of Aesculus hippocastanum L.

本文就欧洲七叶树的组织培养和体细胞胚发生以及植株再生进行了系统研究，主要结果如下：以植物细胞具有全能性的理论为依据，以欧洲七叶树幼嫩叶片为外植体，进行体细胞胚胎发生研究，研究结果表明，诱导愈伤组织的适宜培养基是MS+2，4-D 2mg／L+KT0.2mg／L，MS+BA 8mg／L+NAA 1mg／L有利于胚性愈伤组织的诱导和增殖，添加ZT 2mg／L或BA 5mg／L和IAA 0.2mg／L的MS培养基有利于体细胞胚发育和成熟，体细胞胚可直接诱导次生胚发生，MS+KT 0.1mg／L+NAA 0.01 mg／L或MS+ZT 0.1mg／L+NAA 0.01 mg／L培养基诱导效果最好，增殖频率分别为214％、256％。

As there were 8.69 bivalents in average occurred to be desynaptic, moreover, the most number of the desynaptic bivalents reached 12 at post diakinsis.

从品种轮回422的群体中发现一不育单株，经细胞学观察证明是发生了联会消失突变，由于该植株的花粉母细胞在减数分裂终变期晚期平均有8.69个二价体发生了联会消失，占二价体总数的72.4%，并且发生联会消失的最多二价体数目为12，根据联会消失的最多二价体数目

The results show that the maximum growth quantity of Nocardia can be achieved after culturing 120 h and obvious selective adsorption of Nocardia on the surface of pyrite and sphalerite can be detected. The maximum adsorption rate on the surface of pyrite is 96.99%, whereas it is less than 20% in the case of sphalerite. Adsorption equilibrium can be attained within 20 min on the surfaces of the two minerals. pH value is the key factor influencing upon selective adsorption, and the difference of adsorption quantity on the surfaces of two minerals is apparent when pH is between 4 and 10. Slurry concentration over 6 g/L is favorable to selective adsorption. Nocardia cell concentration, stirring speed and temperature have no obviously effect on selective adsorption.

结果表明：培养120 h后诺卡氏菌达到最大生长量；诺卡氏菌在黄铁矿和闪锌矿表面发生明显的选择性吸附，在黄铁矿表面的最大吸附率可达到96.99％，而在闪锌矿表面的吸附率大都在20％以下；诺卡氏菌在两种矿物表面于20 min内即可达到吸附平衡； pH值是影响诺卡氏菌在两种矿物表面发生选择性吸附的关键因素， pH在4～10之间时，选择性吸附现象明显；矿浆浓度超过6 g/L时有利于发生选择性吸附；细胞悬浊液浓度、搅拌速度和温度对吸附效果影响不大，均可产生选择性吸附。

Meanwhile,HDAC1 acetylation level is significantly increased.The overexpression of HDAC1 can promote erythroid cell proliferation and inhibits induced differentiation,the knockdown of HDAC1 or 2 inhibits erythroid cell proliferation and promotes induced differentiation.We also found that HDAC1 affects GATA1 mediated transcription activity.Thus our data revealed that HDAC1 may negatively regulate GATA1 mediated transcription and suggest that the dynamic regulation of GATA1 associated NuRD/MeCP1/HDAC1/HDAC2 complex may determine the onset of erythroid differentiation programs.Moreover,this study will eventually help to design new therapeutic approaches in treatment of leukemia.

研究发现在被诱导分化的小鼠红细胞白血病细胞中与GATA1相结合的HDAC1被乙酰化并失去活性，在血细胞中过表达HDAC1能够促进血细胞的增殖并抑制分化，反之在血细胞中敲除HDAC1或HDAC2能抑制血红细胞的增殖并促进分化，而且HDAC1能够负调控GATA1的转录活性，GATA1与NuRD/MeCP1复合体之间的动态调控，决定血红细胞分化的发生和发展，并为探索白血病的致病机理奠定了理论基础。

Extraction in crustaceans, salmon, shrimp, phosphorus, red algae astaxanthin, and removal of reactive oxygen species inhibit the capacity of the antioxidant power is 10 times more carotene, Q10 150 times, 550 times the vitamin can promote cell regeneration, slow down premature skin aging occur, and add the green tea extract can prevent the skin caused by ultraviolet radiation caused by aging, protecting cells to reduce the damage of UV on cell DNA, is effective against free radicals and prevent skin aging.

效用：萃取於甲壳类、鲑鱼、燐虾、红藻的虾红素，具有抑制及清除活性氧的能力，其抗氧化力是胡萝卜素的10倍、Q10的150倍，维他命的550倍，能促进细胞再生，延缓肌肤老化过早发生，并添加绿茶萃取能防止因紫外线造成所造成的皮肤老化，保护细胞减少紫外线对细胞DNA的伤害，有效对抗自由基，防止肌肤老化。

Fission A type of asexual reproduction in which a parent cell divides into two daughter cells genetically identical to the parent. Binary fission occurs in many unicellular organisms, such as protoctists, bacteria, and fission yeasts.

裂殖：无性生殖的一种类型，指一个母细胞分裂成两个与母细胞相同的子细胞，二分裂发生在许多单细胞有机体中，如原生生物、细菌和裂殖酵母。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。