细胞发生

In order to investigate the expression of Lrrcl0 during cardiogenesis, an in vitro cardiogenesis model was developed by using P19 cells which underwent differentiation induced by DMSO.

为探讨Lrrc10在心肌细胞分化过程中的表达，采用DMSO诱导P19细胞分化，建立体外心肌发生模型，显微镜观察细胞形态变化，以心α-MHC和β-MHC作为心肌分化的标志，RT-PCR检测分化过程中各基因的表达。

Spontaneous differentiation of ESCs and iPSCs into cardiomyocytes is however limited. To elucidate the regulatory mechanisms and effectively differentiate these pluripotent cells into specific cardiomyocytes are crucial to obtain fundamental knowledge in cardiogenesis, screen drugs and promote the usage of these cells in replacement therapy. This review summarizes the current state of differentiation of cardiomyocytes from mouse and human ESCs and their regulatory factors.

但这些多能干细胞向心肌细胞自发分化的效率非常低，因此，如何有效地诱导这些多能干细胞向心肌细胞的定向分化对深入认识心肌发生发育的关键调控机制和实现其在药物发现和再生医学，如心肌梗塞、心力衰竭的细胞治疗以及心肌组织工程中的应用均具有非常重要的意义。

Spontaneous differentiation of ESCs and iPSCs into cardiomyocytes is however limited. To elucidate the regulatory mechanisms and effectively differentiate these pluripotent cells into specific cardiomyocytes are crucial to obtain fundamental knowledge in cardiogenesis, screen drugs and promote the usage of these cells in replacement therapy.

但这些多能干细胞向心肌细胞自发分化的效率非常低，因此，如何有效地诱导这些多能干细胞向心肌细胞的定向分化对深入认识心肌发生发育的关键调控机制和实现其在药物发现和再生医学，如心肌梗塞、心力衰竭的细胞治疗以及心肌组织工程中的应用均具有非常重要的意义。

MethodsThe cells of human gastric cancer cell line SGC7901 was treated respectively with Chrysin at different concentration 10、20、40、80μM for 48h. The proliferation inhibitory rate was measured by MTT assay. Acridine orangestaining and flow cytometry were used to detect apoptosis. Western blot assay was used to detect the expression of apoptosis related genes NF拨B,Bcl2,Bax.

方法分别用10、20、40、80μM的ChR处理人胃癌细胞株SGC7901 48h，采用MTT比色法检测ChR对SGC7901细胞的增殖抑制效应；采用丫啶橙染色、流式细胞术检测ChR诱导SGC7901细胞凋亡的发生；应用Westernblot法检测凋亡相关基因NF拨B、Bcl2、Bax的蛋白表达，并用计算机图像分析软件进行半定量分析。

During EMT, the originally cuboidal epithelial cells transform into unanchored, mesenchymal, spindle-shaped, fibroblast-like cells.

当EMT发生时，原来呈立方体的表皮细胞会转变成游离且型态梭状类似纤维组织母细胞的细胞。

AIM: To investigate the anti-cancer effect of cytotoxic T lymphocytes activated by sensitized dendritic cells.

目的：研究树突状细胞激活的细胞毒性T细胞的抗肿瘤及预防肿瘤发生的作用。

Through upregulating the production of MMPs in deciduas and chorionic villi, the upregulation of the expression of EMMPRIN in syncytiotrophoblast and cytotrophoblast column of the villi in the threatened abortion can degenerate deciduas and denudates embryo.

发生先兆流产时合体滋养细胞、细胞滋养层柱所表达的EMMPRIN增强可能通过上调绒毛及蜕膜组织中基质金属蛋白酶的水平，降解细胞外基质，使绒毛剥离、蜕膜组织剥脱。

The place and time of cell proliferation are just in accordance with those of the appearances of stem cells and stem-cell blastemas, which means that cells in those areas mentioned above dedifferentiate forming stem cells which proliferate too.

这些分裂细胞在位置和时间上与干细胞及干细胞原基的出现一一对应，表明上述几处发生了细胞的脱分化，形成了干细胞，进行着细胞增殖。

In the late proliferative and secretive phases, expression of ERα in stromal cells significantly decreased to the level observed in the desquamative phase Differently, no clear expression of ERβ was detected in stromal cells in the late proliferative phase. However, its expression appeared again in the secretive phase.

结果显示： 1ERα和ERβ在恒河猴子宫内膜的上皮细胞、基质细胞中均有表达，其表达水平在正常月经周期中发生周期性变化：上皮细胞中两种受体的表达水平从增殖期开始逐渐升高，到增殖晚期最高；分泌期开始下降，直到月经期的水平。

Results NF-κB were involved mainly in regulation of express of genes related to inflammatory reaction. NF-κB expressed in vascular smooth muscle cell, endotheliocyte and macrophage involved in the development of AS.

结果 NF-κB主要参与许多与炎症反应有关的基因的表达调控，在参与AS发生发展的血管平滑肌细胞、内皮细胞和巨噬细胞内均有NF-κB表达。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。