细胞内的

The increases in the cell density in the sutures of the treated groups were higher as compared to the two controlled groups for 3 7 14days indicating that cellular hyperplasia in the expanded sutures were accelerated by the protraction .The cell density in the palatomaxillary sutures and in the frontomaxillary sutures differed in increase ways at the two time points of 21th day and 28th day suggested that the mode of bone formation in the circummaxillary sutures is different from one another..5 The expression of Proliferating Cell Nuclear Antigen were always higher than the controls in the course of this study,which i

而在21、28天时间点两个骨缝与对照组相比在相同时间点增长程度明显不相一致，提示我们不同的上领骨周围骨缝在前牵引作用下改建方式过程可能不一。5、在上领前牵引作用下，上领骨的额领缝内的PCNA的阳性表达一直高于对照组，提示前牵引促进上领骨周围骨缝内细胞增殖活动增强。

The HPV positivity amongst the group of women with no cervical abnormality was 43%, while that in women with cervical dysplasia and cervical cancer was 81.2% PCR products from 89 HPV positive cases were genotyped by LiPA, of which 49 cases were single HPV infected concerning 11 different HPV types and the commonest type was HPV-16, occurring in 25(51%) of all single HPV infected cases. The other 40 specimens contained multiple HPV types comprising 16 different HPV types. Although double infections(n=25) prevailed, triple(n=9),quadruple(n=3) and quintuple(n=3) infections were also found. PCR products of four HPV positive cases failed to be classified by LiPA. Sequencing analysis revealed that these 4 cases were HPV-66 which was not included in LiPA probes. Follow-up data of 12 cases confirmed the HPV genotyping results. Conclusion The LiPA for HPV genotyping is easy to perform.

结果 155例妇女子宫颈刮片中HPV DNA检出率为60%，其中在宫颈细胞学检查正常或仅有炎症病变的妇女中HPV DNA阳性率为43%，而在宫颈细胞增生不良或宫颈细胞癌的妇女其阳性率为81.2%。93例HPV阳性的标本中，89例利用LiPA成功地作出了基因分型，其中单独一型HPV感染为49例，涉及11种不同基因型HPV，最常见的型别为HPV 16，占单独感染的51%(25/49)；另40例为不同型别HPV重叠感染，涉及所有16种HPV基因型别，二重感染占主导地位(n=25)，同时也检测出其它多重感染。4例HPV阳性的标本应用LiPA未能作出基因分型，DNA序列分析显示这4例为HPV 66感染，此型别不包括在LiPA所标记的探针内。12例随诊资料显示了LiPA的物异性及高度的重复性。

Cells in EGL are generated after birth. In contrast Purkinje neurons are born before birth, which receive main innervations of climbing fibers from the inferior olivary nucleus and parallel fibers from the internal granule cells.

与浦肯野氏神经元在出生前产生这一点不同的是，EGL中的细胞在出生后产生，它们接受从前脑olivary核团发出的攀援纤维的主要神经投射，以及从内颗粒细胞发出的平行纤维的神经投射。

With the pose of aquaporin and the detection of ocular different tissue specificity aquaporin, some researchers believe the expression of AQP1 in trabecular meshwork cells maybe the major factor to GIG, some also suggest that periocular or physical

近年来随着水通道蛋白概念的提出和眼内不同组织特异性水通道蛋白(aquaporin，AQPs)的检出，有学者认为，小梁细胞AQP1的表达可能为皮质类固醇激素引起眼压升高机制的研究带来新的突破，也有学者推测，眼局部或全身使用皮质类固醇激素可能使小梁细胞出现AQP1的异常表达和结构改变，致使房水转导功能下降，眼压升高。

The human Rad9, a homologue of yeast Schizosaccharomyces pombe rad9, is a member of the Rad family of checkpoint proteins. It is involved in detection of DNA damage, cell cycle arrest, and DNA repair. Although considerable information about hRad9 and its function has been accumulated, its behavior in malignant cells has not been examined.

人类的Rad9蛋白为Schizosaccharomyces pombe Rad9蛋白的同源蛋白，其为checkpoint rad genes产物中的一员，是一个在演化上具有高度保留性的蛋白。hRad9在细胞内扮演著许多重要的角色，包括侦测DNA的受损、调节细胞周期的进、执 DNA 的修等等。

After administration of L-N〓-nitro-Arginine, a specific antagonist of NOS, it was found that the basal and stimulated NO release of blood vessels (aorta, internal carotid, renal and mensenteric artery) was decreased further. The increase of coronary blood flow stimulated by Ach was also reduced further, while the platelet aggregation degree and erythrocyte aggregation index increased significantly. Pathological examination indicated that aortic endothelium was destroyed, the blood vessels in cerebral, cardiac and renal tissues were hypertrophied further and some were almost occluded. The above fin dings resulted in SHR feeded with L-NNA having high incidence of stroke rate and high degree of renal cirrhosis when compared to control SHR. The infarct and hemorrhagic focuci in cerebral tissues, infarct focuci in cardiac tissues, atrophy and hyalinedegeneration of renal glomeruli and degeneration even necrosis of renal tubuli in renal tissues were al so found. The increase ratio of brain and heart to body weight and decrease ratio of kidney to body wei ght further demonstrated that the cerebral, cardiac and renal injuries were aggravated.

在上述结果的基础上进一步给予SHR NOS特异性拮抗剂左旋亚硝基精氨酸后，血管(胸主、颈内、肾及肠系膜动脉)NO基础释放及激动剂刺激释放进一步减少，Ach刺激冠脉流量的增加和胸主动脉内膜NOS活性也进一步减少，血小板聚集程度及红细胞聚集指数显著上升，病理切片显示胸主动脉内皮细胞破坏明显，脑心肾组织内的血管进一步增厚甚至几乎阻塞，导致饲L-NNA的SHR缺血性及出血性脑卒中发生率显著高于对照SHR，脑体重比显著升高；心肌内出现明显的缺血梗塞疤痕灶，心体重比显著升高；肾小球明显萎缩、玻璃样变性，肾小管也变性甚至坏死，使肾硬化程度显著增加呈颗粒性固缩肾，肾体重比也显著减少。

The expression of GFAP in ILN was significant at 60 mm and it decreased obviously at 120 min after animal model induced. Conclusion Behavior changes in rats are mediated by visceralgia, which induces acute colitis. The change of GFAP in gliocyte, which is closely related with pain, emerged early and remarkably. The change of ILN, which is intensely related with emotion, appears lain.

大鼠痛行为学的变化是由于急性炎症引起的内脏痛而导致，与疼痛变化密切相关的胶质细胞中GFAP在脊髓内反应早且明显，而在与情绪变化密切相关的丘脑内的板内核群中变化相对较晚。

Feed additives, including mannnanoligosaccharides, will reduce intestinal colonisation and shedding as salmonella with type-1 fimbria are agglutinated by the mannose component within the lumen and are excreted without adherence to enterocytes.

由于携有1型菌毛的沙门氏菌易与动物肠腔内的甘露糖分结合而脱离肠上皮细胞被排出体外，因此，选择和使用合适的饲料添加剂尤其是甘露寡糖等，将有助于降低沙门氏菌在家禽肠道内的增殖速度和减少排毒量。

Results The survival area and quality of avulsed flap in the experimental group were superior to that of control group after 15 days of operation, and the hemorheological items were markedly changed at 5 days after operation. Conclusion The better flap survival after orthotopic transplantation in avulsion injury can be improved by intravascular low level He-Ne laser irradiation through changed superoxide dismutase activity and hemorheological items in optimal irradiation intensity.

结果 术后15天治疗组撕脱瓣的成活面积、成活质量均明显优于对照组P结论低能量He-Ne激光血管内照射的生物学效应存在最佳的照射强度总量，在最佳的照射强度条件下，通过改变细胞内超氧化物歧化酶活性及血液流变学参数促进原位回植术后的撕脱瓣良好成活。

Itamin D from the skin and diet is metabolized in the lier to 25-hydroxyitamin D (Figure 1), which is used to determine a patient's itamin D status1,2,3,4; 25-hydroxyitamin D is metabolized in the kidneys by the enzyme 25-hydroxyitamin D-1-hydroxylase (CYP27B1) to its actie form, 1,25-dihydroxyitamin D.1,2,3,4 The renal production of 1,25-dihydroxyitamin D is tightly regulated by plasma parathyroid hormone leels and serum calcium and phosphorus leels.1,2,3,4 Fibroblast growth factor 23, secreted from the bone, causes the sodium–phosphate cotransporter to be internalized by the cells of the kidney and small intestine and also suppresses 1,25-dihydroxyitamin D synthesis.5 The efficiency of the absorption of renal calcium and of intestinal calcium and phosphorus is increased in the presence of 1,25-dihydroxyitamin D (Figure 1).2,3,6 It also induces the expression of the enzyme 25-hydroxyitamin D-24-hydroxylase (CYP24), which catabolizes both 25-hydroxyitamin D and 1,25-dihydroxyitamin D into biologically inactie, water-soluble calcitroic acid.2,3,4

从皮肤和食物来的维生素D在肝中代谢为25-羟基维生素D（图1），被用来决定病人体内维生素D情况的1，2，3，4；25-羟基维生素D在肾中被25-羟基维生素D1羟化酶（CYP27B1）转变为有活性的1，25-二羟基维生素D 。1，2，3，4由肾产生1，25-二羟基维生素D是被血浆甲状旁腺激素和血清钙，磷水平紧密调节。1，2，3，4由骨分泌的成纤维细胞生长因子23使钠磷协同转运蛋白被肾和小肠细胞内化及抑制1，25-二羟维生素D合成。5 在1，25-二羟基维生素D作用下肾和小肠吸收钙及磷的效率增高(图1)。2，3，6 它也包括25-羟四- 24 -羟化酶的表达(CYP24)，且将1，25二羟基维生素D和25羟基维生素D异化成无生物活性，水溶性的维生素D3-23羧酸。2，3，4

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。