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In vitro and in vivo experiments were also performed on minigenes encoding tumor antigen peptides carried by vaccinia virus.

受体介导的细胞内吞在免疫系统的细胞中是一种相当常见的现象,这一现象主要见于专职抗原递呈细胞如树突状细胞、巨噬细胞和B细胞。

Candidum root and surrounded it, and later penetrated the velamen cells.Or mycorrhizal fungus penetrated the exodermal passage cells through the velamencells and further infected the cells of cortex, and then formed pelotons in the corticalcells.

真菌AR-15由根被侵入外皮层通道细胞,在外皮层通道细胞内形成菌丝结,进一步向皮层细胞侵染,从而形成内生菌根,紧靠外皮层的皮层细胞具有多个细胞核和核仁,还发现细胞核正在进行穿壁运动。

Integration was the fundamental function of CNS in exercise, namely controlling the voluntary movement and producing an adaptative reaction to the stimuli from internal and external environment.

研究背景:细胞凋亡是一种形态上明显区别于细胞坏死的细胞死亡方式,在控制多细胞生物生长发育、维护内环境相对稳定等方面具有重要作用。

The results showed as followed:low level NO could keep Sertoli Cells' microtubule and cell viability normally,and high level NO could increase the activity of p-38MAPK of cells, decrease antioxygen ability and cell secretion and destroy the structure and distribution of microtubule.

结果表明,低浓度NO能维持支持细胞正常的骨架和活力,而高浓度NO能提高SC内p38MAPK的活性,降低抗氧化酶的活性和破坏细胞内微管的结构和分布,甚至细胞的分泌功能。

Morphometry of numerical density and electron probe X-ray quantitative microanalysis were used to measure the alterations in the number and calcium content of chromaffin granules in adrenal medulla cells during emergency reaction of restrained rats.

采用电镜细胞立体形态计量法及电镜X射线显微定量分析术,对制动应急大鼠的肾上腺髓质细胞内嗜铬颗粒数密度和颗粒内Ca浓度变化进行测量。

The main pathological findings include a desquamative interstitial pneumonia-like reaction with intra-alveolar macrophages and numerous large multinucleated histiocytes that ingested inflammatory cells were admixed with macrophages.

GIP主要病理表现有脱屑性间质性肺炎样反应,即在肺泡腔内有巨噬细胞和大量的多核巨细胞聚集,位于肺泡腔内的多核巨细胞内可见被吞噬的炎性细胞,是GIP的特点。

Objective To study the cell proliferation in endolymphatic sac during the secondary immune response in inner ear.

研究表明,内耳受到抗原激发时,内淋巴囊局部可聚集包括免疫活性细胞在内的大量炎症细胞参与免疫反应,说明内淋巴囊在内耳免疫中具有重要作用。

As an immunomodulator NO may play a role like a double-edged sword since it expresses both in immuonchalleged and immunosspresed states. 2. After received external stimulus the morphology of ependyma of SFO could be changed and varied with time course, particularly its cellular apoptosis do occur and earlier than the ordinary areas of the brain. 3. Astrocytes in SFO could express cFos protein induced by LPS, suggesting the cells may maintain homeostasis in the brain in a longer period and modulate immune state of the brain. 4. As a CVO, SFO may sense changes of blood-bearing immunosignals earlier and instantly response to them, thus as one of windows of the brain SFO do take part in immunomodulation within the brain.

通过我们的实验结果我们可以得出这样一些初步的结论:1、一氧化氮作为免疫调质参与了机体免疫,它既能在免疫激发状态下又可在免疫抑制状态下进行表达提示,NO在脑内免疫调节中的作用可能是双向的。2、穹窿下器的室管膜形态在接受外界刺激后,随着时间的变化而不同,扫描电镜下的凋亡形态虽需进一步证实,但室管膜细胞确实发生了凋亡,并且穹窿下器发生的较早。3、穹窿下器内的星形胶质细胞在给予大肠杆菌后确实可以表达c-fos蛋白,并可能通过自身的激活来较长时间的维持体液的动态平衡,调节脑内免疫状态。4、穹窿下器作为感受性室周器官之一,能够较早的感受血携免疫信息的改变并及时作出反应,可能作为外周免疫信息进入脑内的窗口之一来参与脑的免疫调节。

The results of study show:1. White pulp and red pulp in parenchyma of spleen of embryo can be obviously discerned after 18 days. Periarterial lymphoid sheath and ellipsoid periarterial lymphoid sheath also can be obviously discerned in spleen of 4 days chicken. T, B lymphocytes in appendix basement of embryo emerge after 20 days. It is the initial shape of cecal tonsil. Crypt structure of conjunction of esophago and stomachus glandularis form obviously at 4 days. It is the initial shape of esophago tonsil. The germinal center firstly emerges in these three organs at 14 days. With the increase of day age, the characteristic structure peripheral immune organs gradually develop mature. Spleen achieve mature at 21 days and cecal tonsil at 35 days.2. IgM~+ and IgA~+ cells in spleen of embryo emerge at 15 days. IgG~+ cell, CD3~+ and CD8~+T lymphocytes of embryo emerge at 20 days. CD3~+, CD8~+ and IgM~+ cells in cecal tonsil of embryo emerge at 20 days. However CD4~+, IgG~+ and IgA~+ cells all emerge in 1 day age chicken out of crust. CD3~+, CD4~+, CD8~+, IgM~+ and IgG~+ cells in esophago tonsil of embryo all emerge at 20 days. However IgA~+ cells emerge in 1 day age chicken out of crust.3. The amount of T, B lymphocytes in peripheral immune organs increase follow with the increase of day age, and hold an upgrade tendency. The amount of T, B lymphocytes in spleen achieved stabilization at 21 days, and in tonsil of esophago and appendix at 35 days.

研究结果表明:1、在组织结构方面,脾脏实质内的白髓与红髓在胚胎18日龄后明显可辨,4日龄雏鸡脾脏中形成明显可辨的动脉周围淋巴鞘和椭球周围淋巴鞘;盲肠基部T、B淋巴细胞在胚胎20日龄时开始出现,即初步形成盲肠扁桃体;食管与腺胃结合处在4日龄时形成明显的隐窝结构,即食管扁桃体初步形成;14日龄时,三种器官中首次出现生发中心;随着日龄的增长,外周免疫器官特征结构不断发育成熟,脾脏在21日龄时达到成熟水平,盲肠扁桃体和食管扁桃体在35日龄时达到成熟水平。2、在T、B淋巴细胞出现时间方面,脾脏中IgM~+和IgA~+细胞在胚胎15日龄时开始出现,IgG~+细胞、CD3~+和CD8~+T淋巴细胞在胚胎18日龄时出现,CD4~+细胞在胚胎20日龄时出现;盲肠扁桃体中CD3~+、CD8~+和IgM~+细胞在胚胎20日龄时开始出现,而CD4~+、IgG~+和IgA~+细胞均在雏鸡出壳后1日龄时出现;食管扁桃体中CD3~+、CD4~+、CD8~+、IgM~+和IgG~+细胞均在胚胎20日龄时开始出现,而IgA~+细胞则在雏鸡出壳后1日龄时出现。3、在T、B淋巴细胞数量变化方面,外周免疫器官中T、B淋巴细胞的数量随日龄增长,整体均呈上升趋势。

Results The intramural capillary lymphatics of rat's rectum were observed in deep lamina propria of tunica membrane and the dermal papilla layer of anal pectin. The intramural capillary lymphatics and lymphatics were both observed in tela submucosa, reticular layer, hypodermis and intermuscular and serosa. The capillary lymphatics in rectums' wall have the similar ultrastructure feature to normal ones. Three kinds of endothelial cells junctions are overlapping junctions, embedding-junctions and end to-end-type junctions. About 21% of cell-junctions are opening types. There are normal organelles and many vesicals in the endothelial of capillary lymphatics.

结果 直肠壁内的毛细淋巴管见於黏膜固有层深部和肛梳区真皮乳头层;在黏膜下层和肛梳区的网状层、皮下组织以及肌层和浆膜层内均有毛细淋巴管和淋巴管,直肠壁内毛细淋巴管的超微结构具有一般毛细淋巴管超微结构的特点,内皮细胞连接有重叠、嵌插和端端连接3种类型,处於开放状态约占21%;胞质内含有一般的细胞器,幷含有大量的囊泡。

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