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Suicide gene therapy is a new experimental form of cancer chemotherapy that is currently being evaluated in human trials. Cytosine deaminase is an enzyme found in a variety of bacteria and fungi where is capable of deaminating cytosine to uracil.

将某些细菌及病毒中特有的药物敏感基因转导入肿瘤细胞,使肿瘤细胞产生某些酶类,将原来无毒的抗病毒药物或化疗前体药物代谢转化成细胞毒性产物而杀伤宿主细胞,这种使肿瘤细胞自杀的基因称为&自杀基因&。

The product of Resmax Skin Series uses pure natural plant Yuanbao essential oil, and contain bioactivators like Vitamine E which can keep skin celluar soft, spring and active, and all kinds of trace elements and so on, which can substitute new-born cell for dead cell constantly; it accelerates metapolism and strengthens secretion of epithelial cells and improves tarnish, tough skin, maintains completeness of intercelluar substances; desalts splash, eliminates wrinkle, and makes skin tightened, smooth and high resiliance.

若诗曼护肤系列产品所采用的纯天然植物元宝精油,富含维持皮肤细胞柔软、弹性、活性之维他命E及各种微量元素等生物活性物质,能使新生细胞不断替代衰老死亡细胞;加速新陈代谢,增强表面细胞分泌能力;由内而外深层美白肌肤,改善晦暗粗糙的肤质;保持细胞间质的完整性;淡化色斑、消除皱纹、使肌肤紧致、滑嫩、富有弹性。

The product of Resmax Skin Series uses pure natural plant Yuanbao essential oil and contain bioactivators like Vitamine E which can keep skin celluar soft spring and active and all kinds of trace elements and so on which can substitute new-born cell for dead cell constantly; it accelerates metapolism and strengthens secretion of epithelial cells and improves tarnish tough skin maintains completeness of intercelluar substances; desalts splash eliminates wrinkle and makes skin tightened smooth and high resiliance.

若诗曼护肤系列产品所采用的纯自然植物元宝精油,富含维持皮肤细胞柔软、弹性、活性之维他命E及各种微量元素等生物活性物质,能使新生细胞不断替代衰老死亡细胞;加速新陈代谢,增强表面细胞分泌能力;由内而外深层美白肌肤,改善晦暗粗糙的肤质;保持细胞间质的完整性;淡化色斑、消除皱纹、使肌肤紧致、滑嫩、富有弹性。

Under the transmission election microscope, we had observed that the state of oocytes arid the cumulus cells around them was tightness, and there were plenty of long and thin microvilli playing the role of connection in the enwrapping. The shape of cumulus cells nucleus was ovate, and the longer and shorter diameters of the cumulus cells were 4.250±0.042μm and 2.750±0.07 μm respectively. The zona pellucida was well proportioned and tightly linking with oocyte. There were great deals of multi-crista mitochondria, lipid droplet and vacuolus. The mitochondria longer and shorter diameters were 0.600±0.106μm and 0.490±0.117μm. Granular nucleoplasma distributed very well in the cell nucleus.

电镜下,卵母细胞外的卵丘细胞紧紧包裹卵母细胞,且与卵母细胞之间有大量细长的微绒毛相联系;卵丘细胞核呈卵圆形,其长径为4250±0.042μm,短径为2.750±0.071μm;透明带均匀,与卵母细胞结合紧密;在皮质区集中分布大量的多峰型线粗体、脂滴和空泡,线拉体长径为0.600±0.106μm,短径为0.490±0.117μm;细胞核中颗粒状的核质分布非常均匀。

As one of the latest detecting approaches, enrichment of exfoliated cells by immunobeads is of high efficiency and tumor specificity.

作为最新型的脱落细胞检测法-免疫磁珠富集粪便脱落细胞检测法除具有一般脱落细胞检测法的优点外,还具有细胞回收效率高、肿瘤细胞特异性高等优点。

Optical microscope, electron microscope and FCM were used to analyse the apoptosis of Hela cell treated with different concentration of DM9811 fermentation filtrates. FCM was used to analyse the cell cycle of the differently treated Hela cells.

用光镜、电镜和流式细胞仪分析不同浓度乳酸杆菌DM9811发酵滤液对Hela细胞凋亡的诱导效果;用流式细胞仪分析不同浓度乳酸杆菌DM9811发酵滤液对Hela细胞细胞周期的影响。

The results demonstrated that laurocapram disrupts the highly ordered lipid structure of stratum comeum and makes the structurs of SC loose,which causes the outermost cell of SC easy to exfoliate and decreases the barrier function of skin for the transdermal absorption of drug;Meawhile, laurocapram penetrating into the intracellular matrix of SC cells fluidizes the filaggrin matrix protein and swells the dermal SC, which could increase the free volume of drug and water content in the SC.

探讨氧酮促进洛美沙星透皮吸收的作用机理。结果表明,氮酮通过以下途径促进药物透皮吸收:(1)作用于表皮角质层细胞间脂质。使角质层变得疏松。细胞间距增大。外角质层细胞易于脱落。降低了皮肤对药物的屏障作用;(2)氮酮进入角质细胞内。与细胞内基质相作用。引起基底角质层肿胀。

The hilling activing of CD3AK+ cells showed significantly higher to K562/VCR cells than to K562 cells, while there was no difference of cytotoxicity between K562 /HHT and K562 cells.

4CD3AK+细胞对K562/VCR细胞的杀伤活性强于对敏感细胞K562,其对K562/HHT细胞的杀伤活性与其对K562细胞的杀伤活性比较,差异无显著性。

Assay that the hilling effect of ART on the cancer cell lines were positively correlated to time and dosage (P.05). The result of flow cytometry demonstrated that ART treatment induced the cancer cell lines arrested in C0/C1 phase and cell apoptosis.

结果 MTT结果显示ART对各株肿瘤细胞均具有显著的杀伤作用(P.05),且其细胞毒作用与时间-剂量呈正相关(P.05);流式细胞仪检测显示,ART使各株肿瘤细胞阻滞于G0/G1期,并诱导细胞凋亡。

METHODS Human IL 6 gene was reconstructed in retrovirus vector and transferred into incasing cells PA317 by lipofectamine mediated method. The clones of the cells transferred with hIL 6 were selected by G418. Targeted NIH3T3 cells were infected with the virus granules secreted from PA317 and also selected by G418. The insertion and expression of hIL 6 gene in NIH3T3 cells were analysed with Southern blot and Northern blot. RESULTS Human IL 6 retrovirus vector (pZIPIL-6) was successfully reconstructed.

利用重组载体构建技术将质粒pUCIL 6 cDNA的目的片段连接于逆转录病毒载体上,并以脂质体介导的方法将重组载体转染包装细胞PA317,以G418筛选克隆细胞,浓缩克隆细胞上清以制备重组病毒液,继之感染NIH3T3细胞后,进行Southern blot和Northern blot分析,检测目的基因在靶细胞的整合与转录水平。

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With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务,乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐,因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。

Closes the eye, the deep breathing, all no longer are the dreams as if......

关闭眼睛,深呼吸,一切不再是梦想,犹如。。。。。。