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It has been used to image the living cells and localize the cell surface ultra structure under near physiological conditions by perfect atomic resolution,was also utilized in the biological process,interactions between druggery and cells,was an important instrument for the study of cell biology.

原子力显微镜,能够在接近生理条件下以具有原子级的分辨率对活细胞进行表面成像和超微结构观察,同时可以研究细胞的生物过程、细胞与药物之间和细胞之间的相互作用,成为细胞生物学研究的一种有效工具。

The atomic force microscopy.It has been used to image the living cells and localize the cell surface ultra structure under near physiological conditions by perfect atomic resolution,was also utilized in the biological process,interactions between druggery and cells,was an important instrument for the study of cell biology.

原子力显微镜,能够在接近生理条件下以具有原子级的分辨率对活细胞进行表面成像和超微结构观察,同时可以研究细胞的生物过程、细胞与药物之间和细胞之间的相互作用,成为细胞生物学研究的一种有效工具。

At last, the classification method is discussed in accidence and a classification method based on decision-tree is presented. In the method, the characteristic parameters of cells are extracted through different methods such as the morphologic, chroma and texture of cells, and then normal cells are eliminated gradually by the means which screens out normal cells from roughly to accurately, and in the end suspicious tumor cells are sorted according to their dubiety.

最后,对细胞的分类方法进行了深入的研究,提出了一种基于判别树的层次分类方法,采用细胞的形态学、色度学和纹理等不同方法获取的细胞特征参数,采取"由粗到精、逐步筛选"的策略逐步剔除正常细胞,并根据可疑程度对疑似肿瘤细胞排序,辅助病理专家的诊断工作。

It was seen that strain 6055 generated three kinds of dextransucrases whose molecular weights were 151 kDa,142kDa and 117kDa,respectively.Among them,the former two ones were found both in supematants and cell wall,while the later was only found in the fermentation liquor.Strain DM 1-2 synthesized two kinds of dextransucrases,and their molecular weights were 183kDa and 142kDa,respectively.The former existed both in cell wall and out of cell,but the later only was located on cell surface.Strain PC 13 produced three kinds of dextransucrases,and their molecular weights were 148kDa, 138kDa and 115kDa,respectively.The former two ones were ectoenzyme while the later was linked to cell.Resembled to strain 6055,strain L4 produced two types of dextransucrases coexisting in supernatants and cell wall with molecular weights of 145 kDa and 136kDa,respectively,but the dextransucrase of 115kDa was only found in free-cells supernatants.

结果显示,菌株6055可产生分子量分别为151kDa、142kDa和117kDa的三种葡聚糖蔗糖酶,其中前两者同时存在于上清液中和细胞表面,而后者只存在于上清液当中;菌株DM1-2可以产生两种葡聚糖蔗糖酶,分子量分别为183kDa和142kDa,前者同时存在于上清液中和细胞表面,而后者仅能存在于细胞表面;菌株PC13可以产生分子量分别为148 kDa、138 kDa和115kDa的三种葡聚糖蔗糖酶,前两者属于胞外酶,而后者与细胞相连;与菌株6055相似,菌株L4可以产生两种同时存在于上清液和细胞表面的葡聚糖蔗糖酶,分子量分别为145 kDa和136kDa,而分子量为115kDa的葡聚糖蔗糖酶只存在于上清液中。

Finally, because cnx-1 can further increase the germ cell death in ced-1 mutant, and the phenotype can be rescued by introducing cnx-1::gfp into the cnx-1; ced-1 double mutants, we suggest that cnx-1 acts in the engulfing cells other than the dying cells during the engulfment process of germline apoptosis.

除此之外,我们亦分析了cnx-1突变下ced-1(e1735)品种虫体之生殖母细胞细胞死亡数量,发现cnx-1突变会额外地再提高ced-1突变下线虫生殖母细胞的死亡数量,且此现象可被外加入之cnx-1::gfp 所消除;这两现象显示出cnx-1在线虫生殖母细胞细胞尸体吞噬过程亦具有功能。

The results showed that there were immature cells (2%-10%) and erythroblast, and puncture of bone marrow revealed myelodysplastic features involving multiple hemopoietic lineages in bone marrow of 19 patients.

结果表明: M6患者的外周血中均可见幼稚细胞(2%-10%)及有核红细胞,骨髓穿刺细胞学检查显示19例伴有多系细胞发育异常,累及二系细胞或三系细胞

The reason is the tumor cells escape the immunosurveillance whose mechanism is very complex. In general, the explanation is based on two aspects, one is that the tumor cells can passively escape the host immunosurveillance when the host immnue state is low and another is tumor cells can actively secrete factors to down-regulate immune function.

肿瘤逃避免疫监视的机制非常复杂,但总体上可从宿主免疫状态及肿瘤细胞等方面来解释,在宿主免疫状态低下时,肿瘤细胞可以被动地逃避免疫监视,但是肿瘤细胞也能主动地释放一些活性物质,下调免疫杀瘤作用,该作用主要通过两个途径,即对免疫细胞功能的调节和免疫细胞数量的调节。

There were enough CD8+T cells in POF women. But their autoimmune reactions were excessive. It should be advanced studied whether CD4+T cells resist the suppression functions of CD8+T cells, the activity of contrasuppression T cells is excess, which cause the function of CD8+ T cells descent and the functions of CD4+T cells increase relatively.

POF患者体内虽有足量的CD8+T细胞,却自身免疫反应亢进,是否与CD4+T细胞对它们的抑制作用具有抵抗性有关,或是因反抑制性T细胞活性过强,致CD8+T细胞功能下降,CD4+T细胞功能相对增强,尚待进一步研究。

Myconrrhizal fungus infected the cortical cells and formed pelotons in the cells, after it penetrated the exodermal passage cells through velamen cells. It is interesting that strain AR-18 also penetrated exodermis from the cortical cell next to it, where mycelium grew vigorously and infected inner cortical cell, even a few mycelium penetrated endodermis while there was no mycelium in the fibrovascular bundles.

真菌AR-15与金钗石斛一起培养时,真菌菌丝与根被细胞密切接触并侵入根被细胞,也可通过侵入根毛进入根被细胞,由根被继续侵入外皮层通道细胞,进一步向皮层细胞侵染;部分根被真菌危害,根部组织内有大量真菌孢子和菌丝。

Hepatic sinusoid capillarization plays an important role in occurrence of portal hypertension. The fenestra of endothelial cells in hepatic sinusoid reduces and the diameter of fenestra decreases. The formation of basement membrane impaires the substance exchange between blood and hepatic cells,which results in oxygen deficiency, metabolic product accumulation and cell necrosis.

肝窦毛细血管化在硫代乙酰胺诱导的肝硬化门脉高压发生中起重要作用,肝窦内皮细胞窗孔减少并减小,内皮细胞下基底膜形成使肝细胞与外界物质交换减少,导致细胞缺氧、代谢产物聚集,肝细胞坏死,最终导致门脉高压的发生。

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