细支气管

The bronchi and bronchioles are tiny tubes through which air passes in and out of the body.

支气管和细支气管是指空气进出人体所经过的细小管道。

"In the lungs, the bronchi further divided into smaller and smaller bronchi, and finally into bronchioles."

在肺里，主支气管又进一步分为越来越小的支气管。最后分成细支气管。

In early COPD, the CT findings are based on hyperplasia of glands and rupture of smooth muscles at bronchus and bronchiole.

早期表现为腺体增生，1级时即可出现细支气管壁平滑肌的断裂，2级时出现支气管壁平滑肌的断裂及胶原纤维的增多。

Results There was no apparent gender difference among 14 patients. 9 patients were younger than 30 years old. Pathological examination showed that bronchial infiltration of eosinophils in 14 patient (100%), thickened basement membrane of the bronchial mucosa in 12 patients (85.7%), proliferation of smooth muscle cells in 11 patients (78.6%), proliferative mucous gland in 9 patients (64.3%), mucous plug in bronchiole in 8 patients (57.1%), and cicatvization of left ventricle in 10 patients (71.4%).

结果哮喘猝死患者无性别差异，年龄30岁以下者9例(64.3%)；病理改变的特点为支气管管壁嗜酸细胞浸润14例(100%)，粘膜基底膜增厚12例(85.7%)，支气管平滑肌细胞增生11例(78.6%)，粘液腺增生、肥大9例(64.3%)，细支气管内粘液栓形成8例(57.1%)；左心室壁瘢痕形成10例(71.4%)，病变主要位于左心室侧壁和心尖部。

Resujts:① The distribution of lesions are mostly symmetrical, extensive, predominant in the middle and lower lung fields, and posterior areas in peripheral;② There are so many HRCT findings of lung, ILD is predominant: intralobular interstitial thickening 46 cases (100%), ground-glass opacity 41 cases (89.13%), peribronchovascular or centrilobular interstitial thickening 40 cases (86.96%), interlobular septal thickening 38 cases (82.61%), irregular linear opacity 37 cases (80.43%), small nodular opacity 34 cases (73.91%), subpleural line 27 cases (58.70%), bmnchiectasis or bronchiolectasis 19 cases (41.30%), patch opacity 18 cases (39.13%), expiratory mosaic sign 15 cases (32.61%), interface sign 14 cases (30.43%), honeycombing 12 cases (26.09%), emphysema or bulla 3 cases, cystic airspace suspected 1 case, and atelectasis suspected 1 case;③ Mediastinum and pleura: multiple small lymphonodi in mediastinum 41 cases (89.13%), pleural thickening or rough 38 cases (82.61%), esophagoectasis 11 cases (23.91%), unilateral little pleural fluid 1 case, and mediastinal emphysema 1 case.

结果：①皮肌炎肺部病变分布呈对称、广泛、偏中下、偏外后的特点；②肺部HRCT表现多样，以肺间质性改变为主：小叶内间质增厚46例(100%)，磨玻璃影41例(89.13%)，支气管血管束增宽或小叶核心增大40例(86.96%)，小叶间隔增厚38例(82.61%)，不规则纤维索条影37例(80.43%)，结节影34例(73.91%)，胸膜下线27例(58.70%)，支气管或细支气管扩张19例(41.30%)，斑片影18例(39.13%)，呼气相马赛克征15例(32.61%)，界面征14例(30.43%)，蜂窝影12例(26.09%)，肺气肿或肺大泡3例，单纯囊状气腔1例，肺不张l例；③纵隔及胸膜：纵隔小淋巴结影41例(89.13%)，胸膜增厚或毛糙38例(82.61%)，食管扩张11例(23.91%)，单侧少量性胸腔积液1例，纵隔气肿1例。

The HRCT findings in patients with BOOP include: 1 patchy consolidation (seen in 80% of cases) or ground-glass opacity (in 60% of cases), often with a subpleural and/or peribronchial distribution; and 2 small ill-defined nodules (30-50% of cases) which may be peribronchial or peribronchiolar.

HRCT上BOOP的表现包括：1、斑片状实变（见于80％的病例）或毛玻璃样影（见于60％的病例），通常位于胸膜下和/或支气管旁；和2、边界不清的小结节（见于30～50％的病例），可于支气管旁或细支气管旁。

The results showed that:(1) In COPD group the alveolar walls were broken. The average area of alveolars was 2.46 times as big as the control group, and the average diameter was 1.42 times as compared with the control group. As the diameter of bronchioles was less than 100μm and 100～200μm respectively, the average area of smooth muscle in bronchioles increased to 3.06-fold and 2.13-fold respectively. By electron microscopic, the proportion of Clara cells of respiratory bronchioles in COPD group decreased, the Clara cells were denaturalized, the proportion of Clara cells containing low density secretory granules increased. The airway resistance was 1.84 times while the dynamic compliance was only 70.45% comparing with the control group.

结果表明：(1)光镜下，COPD组大鼠与正常对照组比较，肺泡壁破坏、肺泡腔扩大，平均肺泡面积和平均肺泡直径分别为正常对照组的2.46倍和1.42倍，在直径＜100μm及直径100～200μm的小支气管，COPD组大鼠支气管平滑肌面积分别为正常对照组的3.06倍和2.13倍；电镜下可见，在呼吸性细支气管，Clara细胞占上皮细胞的比例下降，细胞变性，含低电子密度颗粒的Clara细胞比例增加；呼吸功能测定可见COPD组大鼠呼气相气道阻力是正常对照组的1.84倍、动态呼吸系统总顺应性为正常对照组的70.45％。

Results CT and HRCT had more sensitivity and specificity than X-ray chest film.There were more image manifestations in HRCT such as grand grass,net,line,nodular,honeycombing,bronchiectasis,honeycombing cyst,peribronchovascular interstitial thickening and irregularity.There were significant difference between them （P.05）.These patients who were suspected IIP had better control and remission after being treated with hormone and immuno-suppressive drug.

结果 胸部CT在诊断方面比常规胸片有较大的优越性，HRCT则有更高的敏感性和特异性，HRCT表现出磨玻璃影、网状、线条、小结节、蜂窝影，支气管扩张、细支气管扩张、支气管壁和血管壁增厚及不规则等征象，12例临床疑诊为间质性肺炎的患者，经胸部HRCT诊断的12例，而胸部平片诊断的仅有2例，二者比较差异有显著性（P.05），HRCT疑诊的IIP患者，经临床激素及免疫抑制剂治疗，病情均得到控制或缓解。

objective to compare image manifestations values between high resolution computerized tomography and x-ray chest film in idiopathic interstitial pneumonia in the elderly.methods we analysed and compared image manifestations between hrct and x-ray chest film with 12 cases of clinically suspected iip in the elderly.results ct and hrct had more sensitivity and specificity than x-ray chest film.there were more image manifestations in hrct such as grand grass,net,line,nodular,honeycombing,bronchiectasis,honeycombing cyst,peribronchovascular interstitial thickening and irregularity.there were significant difference between them （p.05）.these patients who were suspected iip had better control and remission after being treated with hormone and immuno-suppressive drug.conclusion it have more significant virtues in hrct to manifest iip in the elderly than x-ray chest film,and it also may manifest iip curative effect.

目的 比较高分辨断层摄影术、x线胸片检查对老年特发性间质性肺炎的诊断价值。方法对12例临床疑诊为间质性肺炎的老年患者，进行胸部hrct与胸部平片检查，并对照分析。结果胸部ct在诊断方面比常规胸片有较大的优越性，hrct则有更高的敏感性和特异性，hrct表现出磨玻璃影、网状、线条、小结节、蜂窝影，支气管扩张、细支气管扩张、支气管壁和血管壁增厚及不规则等征象，12例临床疑诊为间质性肺炎的患者，经胸部hrct诊断的12例，而胸部平片诊断的仅有2例，二者比较差异有显著性（p.05），hrct疑诊的iip患者，经临床激素及免疫抑制剂治疗，病情均得到控制或缓解。结论 hrct表现老年间质性肺炎的特点明显高于胸部平片，且hrct可以反映间质性肺炎的疗效。

Fiberoptic brochoscope is a useful instrument to diagnose lung cancer. Bronchial lavages using fiberoptic bronchoscope could not only improve the diagnosis of lung cancer, but also cost little. In addition, bronchial lavages, called"fluid biopsy", is helpful to diagnose primary of secondary carcinoma locating in respiratory tract, including peripheral lung cancer, bronchioalveolar carcinoma, pulmonary metastatic carcinoma and lymphoma.

纤维支气管镜检查是诊断肺癌的有力武器，支气管灌洗不仅能稳定地提高肺癌检出率，而且价格便宜，此外，能研究常规支气管镜未见异常的肺部病变，有助于诊断呼吸道原发性或继发性恶性肿瘤，包括周围型肺癌，细支气管肺泡癌，肺转移癌，癌性淋巴管病，肺部淋巴瘤等，被称为&液相活检&。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。