组织蛋白酶

This paper studied the effects of types of medium, conditions of culture, different kinds of carbon and nitrogen sources and plant growth hormone in medium component on Agave sisalana tissue and cell culture for inducement of Agavain—SH.

本论文研究了剑麻组织和细胞培养中培养基类型、培养条件、培养基组成中不同碳源、氮源和激素对愈伤组织细胞生长和蛋白酶活力的影响；。。。

Objective To study the expression of matrix metalloproteinase - 9 and tissue inhibitor of metalloproteinase - 1 protein in human endometrial carcinoma tissue and its corelation with clinicopathologicol features.

目的 研究基质金属蛋白酶-9及其组织抑制物-1在子宫内膜癌组织中的表达及其临床病理学意义。

The matrix metalloproteinases are a family of functionally related zinc-containing enzymes that denature and degrade fibrillar collagens and other components of ECM.

基质金属蛋白酶组织抑制剂-1(tissue inhibitor of metalloproteinase-1，TIMP-1)是MMPs的内源性组织抑制剂，是体内调节MMPs活性的重要物质。

Results The expression of MMP-2 and MMP-9 was detected in normal anterior hypophysis, non-invasive and invasive macropituitary adenomas.

采用免疫组化SP法检测正常垂体前叶组织、侵袭性和非侵袭性垂体腺瘤组织中基质金属蛋白酶-2和9及其组织抑制因子的表达，结果进行统计学分析。

Immunohistochemical stains were used to show the tryptase + mast cell and the chymase + mast cell distribution in order to observe the change of the mast cell in the model group, the control group and the treatment group.

取右下肺组织，用抗类胰蛋白酶单克隆抗体和抗类糜蛋白酶单克隆抗体免疫组织化学染色观察实验组与正常组之间肥大细胞数量的变化，HE染色观察肺组织一般病理变化。

Through upregulating the production of MMPs in deciduas and chorionic villi, the upregulation of the expression of EMMPRIN in syncytiotrophoblast and cytotrophoblast column of the villi in the threatened abortion can degenerate deciduas and denudates embryo.

发生先兆流产时合体滋养细胞、细胞滋养层柱所表达的EMMPRIN增强可能通过上调绒毛及蜕膜组织中基质金属蛋白酶的水平，降解细胞外基质，使绒毛剥离、蜕膜组织剥脱。

Objective To study the relationship between IL-1,MMP-13and pathogenesis of knee osˉteoarthrosis.Methods IL-1and MMP-13were measured concurrently in synovial fluid samples from23patients with mild OA,28patients with severe OA and6patients with disciform meniscus.The determinations of positive rate of cells in genual synovium with IL-1and MMP-13were carried out using immunohistochemical techonology.

目的 探讨白细胞介素-1（IL-1）、基质金属蛋白酶-13（MMP-13）在膝关节骨性关节炎发病中的作用方法提取23例OA病变轻微患者、28例OA病变严重患者、6例对照者的滑膜组织及关节液，采用免疫组织化学方法检测膝关节滑膜组织中IL-1、MMP-13的阳性细胞率及通过夹心ELISA法测定膝关节滑液中IL-1、MMP-13含量。

This article defines the levels of matrix metalloproteinase-2 and matrix metalloproteinase-9 in periosteum of the congenital pseudarthrosis of tibia, and elucidate the pathogenesis.

明确基质金属蛋白酶2和基质金属蛋白酶9在先天性胫骨假关节病变处骨膜组织中的含量，探讨其与发病机制的关系。

Objective: In study of atherosclerosis, extracellular matrix of plaque is closelyrelated to the evolution of AS ,the balance of MMPs and TIMPs is very important to maintain the dynamic equilibrium of ECM, and the creation of appropriate animal models of AS is the important prerequisite for studying pathogenesis of AS and therapeutic programs.

目的：在动脉粥样硬化的研究中，斑块的胞外基质成分的变化与疾病的进展有重要联系，而基质金属蛋白酶和金属蛋白酶组织抑制物的平衡对维持ECM的动态平衡有着十分重要的作用。

MMPs are usually secreted as latent, inactive proenzymes, which need to be activated (Fig 1 ), and/or are bound to their native inhibitors, the tissue inhibitors of metalloproteinases.8 Activation may involve proteolysis and/or oxidation of the latent enzyme.8 Proteolytic activation of the proenzymes cleaves the propeptide sequence, which masks the active site of the latent enzyme.

金属蛋白酶常以无活性的酶原方式分泌，而后者要么需要被激活要么与附近的或组织中金属蛋白酶抑制物结合。激活作用包括了具有潜在酶的蛋白水解作用或氧化作用。酶原的蛋白水解激活作用能将掩盖活性部位的潜在酶的前肽序列破坏。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。