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组织蛋白酶

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Expression analyses identified increased expression of numerous TGF-beta-related genes that regulate cell proliferation and survival and plausibly contribute to myxomatous valve disease.

他们注意到,多数效应器分子的表达增加降低了TGF-β的信号作用,包括可诱导TGF-β的H3基因、内皮素-1、组织抑制因子金属蛋白酶1、致骨形态学发生的蛋白和&调节细胞增生和存活可能还有促进粘液瘤性疾病的基因&。

Brane, such as synoviocytes, macrophages, osteoclasts and TNF-αvv acts on different kinds of cell in synovial memchondrocytes, which can produce metalloproteinase,collagenase, stromelysin and so on, further induce pannus formation, joint inflammation, bone erosion and cartilage degradation.

TNF-α可作用于RA关节组织中的滑膜细胞、巨噬细胞、软骨细胞和破骨细胞,使这些细胞活化,产生金属蛋白酶、胶原酶、基膜溶解酶等,导致局部炎症反应和血管翳形成,进一步引起软骨破坏和骨侵蚀。

This pattern is characterized by the combination of pro-MMP-2 and membrane type 1 (MT1)-MMP expression, which drie pericellular generation of actie MMP-2 and local degradation of normal lier matrix. In addition there is a marked increase in expression of TIMP-1 leading to a more global inhibition of degradation of fibrillar lier collagens by interstitial collagenases (MMP-1/MMP-13). These pathways play a significant role in the progression of lier fibrosis.

其降解肝正常基质,同时抑制引起肝纤维化的纤维胶原降解,这种情况的特点是前明胶酶A合成和膜型1-MMP表达,使得小叶内细胞激活MMP-2和降解当处的正常肝基质,此外血浆1型组织基质金属蛋白酶抑制剂(TIMP-1)明显升高引起广泛的抑制间隙胶原酶(MMP-1/MMP-13)对纤维肝脏胶原的降解。

But how to inhibit the activation of NF-κB to reduce the production of inflammatory cytokines, chemokines, and other phlogistic substances remains an unresolved problem.

乌司他丁是一种广谱蛋白酶抑制剂,能抑制多种蛋白、糖和脂类水解酶的活性,减少炎性介质的过度释放,改善微循环和组织灌注。

Plant proteases are enzymes which solubilize plant proteins and browningis a chemical reaction resulting from high temperatures.

植物蛋白酶是一种能够溶解蛋白质的酶,褐变是植物组织在高温条件下的一种化学反应。

Methods The Epidermal stem cell were isolated by adhering to collagen type IV after obtained by digesting human foreskin with Dispase Ⅱ and Tryp and culture in vitro in K-SFM. The expressions of β1-integrin and keratin 19 (K19) in epidermal stem cell were detected with immunocytochemical methods,and the colony forming efficiency was also studied .

中性蛋白酶和胰蛋白酶两步法从手术切除的人包皮组织中分离表皮层和真皮层,并获得表皮单细胞悬液,采用Ⅳ型胶原铺板选择性粘附、分离和角质形成细胞无血清培养基培养表皮干细胞。

Methods:The expression of mast cell tryptase and chymasec were examined in 37 cases of normal uterus with immunohistochemical double labeling techniques.

选取37例正常子宫组织,用双重免疫组化染色法检测肥大细胞中类糜蛋白酶和类胰蛋白酶的表达。

Methods: By using immunohistochemical analysis EMMPRIN expressions in chorionic villi and deciduas were evaluated.

目的 探讨先兆流产时绒毛及蜕膜组织中细胞外基质金属蛋白酶诱导因子的表达情况。

The result indicated that after the yellow seedlings of wheat was triturated by the high speed tissue triturating machine, high purity mitochondria could be exacted by density gradient centrifugation, and then the mitochondria was ruptured by the 5% SDS and protease K, and the protein was wiped off by organic liquid, pure mtDNA could be extracted.

结果表明,经高速组织匀浆捣碎机研磨小麦黄花苗,简易的密度梯度离心技术快速抽提大黄的高纯度的线粒体,5% SDS和蛋白酶K裂解线粒体及有机溶剂抽提去除蛋白质可获得纯度较高的mtDNA。

Objective To detect the rat pancreatic elastase II mRNA in rats.

目的 检测大鼠组织中胰腺Ⅱ型弹性蛋白酶mRNA的表达。

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