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Although, in our study the functional characteristics of these T cells was not investigated, we can speculate that in HBsAg inactive carriers, a dynamic population of HBV specific T cells, both in the liver and periphery exists, that is able to produce antiviral cytokines (i.e. IFN-gama) and thus suppress HBV replication without cytolytic liver damage.

我们虽然没有研究这些细胞的功能特征,但是可以推测:非活动性乙肝病人机体内,有一个具有动态数量的HBV特异性T细胞群,在肝组织和外周都存在,它们能够产生抗病毒因子抑制病毒的复制,同时不造成肝细胞损伤。

We have performed systematical studies on intrauterine transmission of hepatitis B virus and our studies suggested that HBV may occur through progressive infection of different placental layers until the virus reaches the fetoplacental circulation, which is the named "transplacental cellular traffic" except through placental tears with transfusion of infected maternal blood into the fetal circulation, which is the named "hematogenous transmission".

我室近年来对HBV宫内传播进行了系列研究,发现了胎盘在宫内传播中的作用,并提出了HBV宫内传播机制的假设:除血源性途径外,还可通过HBV在胎盘组织内的&细胞传递&途径,即HBV可以从母体蜕膜细胞通过&逐层转移&至胎儿绒毛毛细血管内皮细胞,导致胎儿感染。

Results Astrocyte of rat optic nerve was cultured and purified,which showed positive reaction to glial fibrillary acidic protein.

组织块原代培养,振荡法分离纯化视神经的星形胶质细胞,对细胞的损伤小、纯度高,是快速得到该细胞的理想途径。

When pea ( Pisum sativum L.,Alaska strain) was grown in short\|day conditions,the apical bud senescence started with the transformation of the bud from vegetative to reproductive growth.DNA fragmentation was detected during the senescence using the terminal deoxynucleotidyl transferase\|mediated dUTP nick end in situ labeling method.The cell ultrastructural changes were similar to apoptosis in animal cells:the apical meristemetic cells underwent the programmed cell death.This wa...

显微、超微结构研究表明,短日照条件下豌豆顶芽的衰老过程是从营养生长锥向花芽的转化,而用DNA原位末端标记、Caspase 8WesternBlot和 14 0bpDNA片断积累的试验结果证明,转化为花芽的整个生长锥细胞发生了编程性死亡,而且其最顶端部分细胞首先发生PCD ,而顶端周围的分生组织细胞逐渐分化出花芽的各部分,但顶芽最后并没有发育成为完整的花,所有细胞就都发生PCD ,从而顶芽衰老

The results showed:(1) The histological changes of KC were in fact a wound-repair process;(2) The increased melanin in KC coordinated with "multi-overlapping screen" effect, a result of multiple layers of "supranuclear cap", was the direct cause of hyperpigmentation of the graft and (3) The hydrolytic disturbance of melanin in KC and the longer life span of the KC were probably the important reasons for the increase of melanin in the epidermis.

结果表明,角朊细胞的组织学改变实际上是一个损伤后修复的过程;角朊细胞内黑色素含量增加及出现的多层次的&核上帽&状分布而形成的&多重帘幕&效应,是皮片过度色素化的直接原因;黑色素在角朊细胞内的降解障碍及角朊细胞更新周期延长可能是表皮内黑色素含量增多的重要原因。

ABSTRACT Objective To discuss the clinical pathologic features and differential diagnosis of mixed germ cell sex cord stromal tumorwith malignant variant of germ cell tumor Methods The clinical pathologic datum and immunophenotype were studied in the case of ovary MGCSCST with malignant variance of germ cell tumor Results The patient's genital anatomy and female phenotype were normal,karotypes was 46xx with uterogestation The tumor tissue consisted of mixed germ cells and sex cord stromal cells with evident malignancy of mixed germ cells There was no atypical structure of gonadoblastoma in tumor tissue Conclusion MGCSCSST has complex morphosis,thus,to prevent misdiagnosis,more samples should be collected and more slices be cut The patient may have prognosis malo when there are high malignant variants of mixed germ cells in tumor tissue

目的 探讨混合性生殖细胞性索间质肿瘤(mixed germ cell sex cord stromal tumor,MGCSCST)伴恶性生殖细胞肿瘤变异型的临床病理特点及鉴别诊断。方法卵巢MGCSCST伴恶性生殖细胞肿瘤变异型的病例进行临床病理特征和免疫表型分析。结果患者生殖器的解剖结构和女性表型正常,染色体组型是46xx,足月妊娠。肿瘤组织由混合性生殖细胞和性索间质肿瘤构成,混合性生殖细胞有显著的恶性特征。瘤组织中没有典型的性腺母细胞瘤结构。结论 MGCSCST有复杂的形态结构,因此更多的取材和切片可以防止误诊,当肿瘤组织中的混合性生殖细胞有高度恶性变异时,患者预后不良。卵巢肿瘤;生殖细胞性索间质肿瘤;免疫组织化学

The expression of HSP70 and HSP70mRNA and the activity of SOD and NOS in uterus were elevated with preventive acupuncture and preventive moxibustion and the influence on the activity of SOD and NOS was mainly refected in 12th and 16th month. It indicated that preventive acupuncture and preventive moxibustion on Guanyuan point could relieve the abnormal activity of center of stress, promote the expression of HSP70 and HSP70mRNA and the activity of SOD and NOS in uterus so as to maintain the normal structure and function and prolong the retrograde degeneration of uterus. It might be one of mechanisms of protecting uterus with preventive acupuncture and preventive moxibustion.

提示逆针灸关元穴对随后更年期大鼠子宫产生保护作用机制可能通过减缓应激中枢的异常活跃状态,提高不同月龄外周子宫组织细胞HSP70及mRNA的表达,以促进组织SOD、NOS活性的增强,对抗应激激素及卵巢功能衰退引起的子宫靶器官的结构及功能的改变,提高机体抗氧化能力,增强NO/NOS的局部调节作用,减轻随后更年期衰老过程中自由基对组织器官的损害及组织器官功能紊乱,对于维持子宫正常的结构和功能,延缓子宫退行性变具有重要作用。

Results After 2 weeks, the number of skeletal myoblasts reached 107 per millilitre. Immunocytochemical analysis showed that over 90% cells were stained positive for myogenin, a factor specific to skeletal myocytes.

结果 采用组织块培养法,2周后成肌细胞的密度可达107/ml,免疫细胞化学分析显示90%以上的细胞呈骨骼肌特异的myogenin抗体染色阳性。

On the other hand, the apoptotic effects of mtDNA depletion in vivo are different from those observed in cultured cells because of the supplementation of pyruvate and uridine in the medium.

另一方面,mtDNA的减除对活体细胞的影响与在细胞培养所观察到之凋亡行为应有所不同,因为在活体组织内细胞并无法获得大量的丙酮酸。

No immunostaining was seen in RPE. Double staining that Kir2. 1 and glutamine synthetase, Kir2. 1 and glutamine synthetase colocalized well. Intense Kir7. 1 immunolabeling was present on the apical surface of all RPE cells and appeared to extend over the length of the apical processes. Na〓, K〓-ATPase expression varied among RPE cells, but in highly expressing cells, it co-localized with Kir7. 1. Immunoreactivity of Kir2. 1、Kir4. 1 and Kir7. 1 acomplished by ABC immunohistochemistry in monkey and human retinae got the nearly same results as bovine.

间接免疫荧光组织化学显示,Kir2.1蛋白主要分布在Müller细胞与神经元相接触的细胞膜区域;与Müller细胞的特异性标记蛋白质抗谷氨酸合成酶抗体双重标记显示其分布特性重叠,在RPE未检测Kir2.1蛋白的免疫活性存在;Kir4.1蛋白集中分布于Müller细胞的内侧突起,与GS蛋白双重标记显示其分布特性重叠,RPE未检测Kir4.1蛋白的免疫活性存在;Kir7.1主要分布于RPE游离面及其突起的全长,与特异性标记RPE突起的Ezrin蛋白完全重叠,Na〓-K〓ATP酶在不同部位的RPE表达不同,Na〓-K〓ATP高表达的RPE细胞与Kir7.1的分布特性重叠。

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Lugalbanda was a god and shepherd king of Uruk where he was worshipped for over a thousand years.

Lugalbanda 是神和被崇拜了一千年多 Uruk古埃及喜克索王朝国王。

I am coming just now,' and went on perfuming himself with Hunut, then he came and sat.

我来只是现在,'歼灭战perfuming自己与胡努特,那麼,他来到和SAT 。

The shamrock is the symbol of Ireland and of St.

三叶草是爱尔兰和圣特里克节的标志同时它的寓意是带来幸运。3片心形叶子围绕着一根断茎,深绿色。