组织细胞的

Another important yet little-appreciated cause of anticancer drug resistance is the limited ability of drugs to penetrate tumor tissue and to reach all of the tumor cells in a potentially lethal concentration. To reach all viable cells in the tumor, anticancer drugs must be delivered efficiently through the tumor vasculature, cross the vessel wall, and traverse the tumor tissue.

另一个重要的但并未受到重视的产生肿瘤耐药的原因是肿瘤药物本身具有有限的穿越肿瘤组织在肿瘤细胞中达到潜在的致死浓度，为了达到肿瘤组织中的活细胞，抗肿瘤药物必须能够有效的穿越肿瘤的脉管系统、穿越血管壁进入肿瘤组织。

It was also found that Cap43 expression in patient with adenocarcinoma was higher than those with squamous cell carcinoma(P.01). Western blot also showed high expression of cap43 in lung cancer. Cap43 expression in mucoid adenocarcinoma was significantly higher than the other pathological types of lung cancer.

免疫印迹也显示，Cap43蛋白在非小细胞肺癌组织中高表达；其半定量结果显示，Cap43蛋白在肺粘液性腺癌组织中的表达量明显高于其它组织学分型肺癌组织(P.01)。

The results showed that exogenous substances could promote the upper leaf area increase, and accommodated the thickness of palisade tissues, spongy tissues and the cell density of palisade tissues dynamic changes, and decreased leaf thickness, loosen the tissue, and increased the potassium content, while reduced nicotine content.

结果表明，外源物质可促进上部叶面积增大，调节叶片栅栏组织、海绵组织厚度和栅栏组织细胞密度的动态变化，促使叶片厚度降低，组织变得较为疏松，促进钾素含量提高和烟碱含量降低。

Some single embryogenic cells produced an embryonic cell and a suspensor cell by the first division and embryonal suspensor masses were produced after several divisions.

胚性愈伤组织中的一些单个胚性细胞经过第一次分裂产生两个细胞，即胚细胞和胚柄细胞，它们继续进行分裂几次以后形成胚性胚柄团结构。

The authers fetched the embryo calvarial peristeum tissue, got human osteoblast by enzyme-assimilating methods and tissue-block culture methods. We observed the morphological change, growth feature and osteogentic capability, of osteoblast during culture in vitro with phase contrast invert microscope, drew the growth curre and identified the cells by alkaline phosphatase dye. At same time, the morphology and bioactivity of 3-5th-generation osbeoblast and anabiotic cells was studied comparatively. 2. titanium particles were examined by scanning electron and the size was determined by semi-automated image analysis. The 3-5 th gereration of human osteoblast were cultured in medium with different concentration of particulates titanium alloy (1mg/ml, 0.1mg/ml, 0.01mg/ml). Cell growth and proliferation was detected by MTT method after 2、4、6 days that particles were added into medium and ALP activity was measured by kit after 4、7、10 days respectively. 3. With above same methods,the 3-5th generation of human osteoblasts were cultured for 3、6、9days after different concentration of particulates titanium alloy (1mg/ml, 0.1mg/ml, 0.01mg/ml) were added into the medium and OPG gene expression was quantified by RT-PCR.

1、取人胚胎颅骨骨膜，采有用酶消化法和组织培养法获取成骨细胞体外培养并传代，观察细胞形态，生物特点及成骨特性，并绘制生长曲线同时碱性磷酸酶染色鉴定成骨细胞以及比较冻存前3-5 代与冻存后成骨细胞的特点。2、电镜下观察钛合金颗粒的形态并测量其粒径，将不同浓度的钛合金颗粒(1mg/ml，0.1mg/ml，0.01mg/ml)与成骨细胞共同培养，分别于第2、4、6 天用MTT 法测量细胞增殖情况及4、7、10天用试剂盒检测碱性磷酸酶活性。3、分别将不同浓度的钛合金颗粒(1mg/ml，0.1mg/ml，0.01mg/ml)与成骨细胞基因培养3、6、9 天用RT-PCR 方法半定量测定骨保护素基因mRNA 的表达。

In resent year, several in vitro models for committed differentiation of ES cells have been described which give rise to a variety of cell types, including hematopoietic, neuronal, chondroitic, osteocytic, endothelial, myogenic, cardiac and smoothes muscle cells, but the committed differentiation into epidermal stem cells have not been reported.

ES细胞为研究基因功能、胚胎发生和个体发育，及组织细胞分化机理提供了理想的模型。近年来的研究表明，适当条件下，ES细胞可定向分化为三个胚层的各种类型的细胞，其中包括向神经元、造血细胞、成骨细胞、心肌细胞、血管内皮、软骨细胞、平滑肌特方向的定向分化。

The results showed that the D50 of Astragalus membranaceus and Epimedium brevicornum ultra-fine powder were 6.82μm and 8.40μm separately. The broken cellular walls of two ultra-fine herbal powder were bigger than those of the commonly cribble, and intact cells were not visible under SEM, and it improved the mixed uniformity. On the contrary, organization blocks of the commonly cribble were clearly discernible, also the shape and granularity were irregular, and the organization cells were still complete. The bulk density and liquidity of Astragalus membranaceus and Epimedium brevicornum increased significantly after ultra-fine Smashing. The component icariin extraction content of the ultra-fine powder was enhanced by 18.31% compared with the cribble by the chromatograph analysis of icariin. At the same time, Astragalus membranaceus polysaccharide and Epimedium brevicornum polysaccharide content of the ultra-fine powder were enhanced by 117.13% and 315.15% compared with the cribble.

结果发现黄芪和淫羊藿经超微粉碎后，粉体的粒度分布中心D_(50)分别为6.82μm和8.40μm，经电镜观察均难以看到完整的细胞形态，只能看到细胞碎片，破壁率远远大于普通粗粉，其混合的均匀度显著提高，而普通粗粉在显微镜下，组织块清晰可见，且形状不规则，粒径分布不均匀，组织细胞仍然完整；超微粉碎后，黄芪和淫羊藿的堆密度和流动性显著增强；通过对淫羊藿有效成分淫羊藿苷的色谱分析，其中淫羊藿超微粉的淫羊藿苷体外溶出量较淫羊藿粗粉中提高了18.31%；同时黄芪、淫羊藿超微粉多糖的提取率分别较黄芪、淫羊藿粗粉提高了117.13%，315.15%。

The mechanism of Si Junzi Tang and panax sapogenol were studied on the effect of gastrointestinal cells protection by applying advanced technology of histochemistry, Holt′s cytodieresis mircocirculation, radio-immunity and subcellular ultrastructure.

进而应用酶组织化学、Holt细胞分裂测定、微循环测定、放射免疫测定、亚细胞超微结构观察等先进技术，研究四君子汤、人参皂甙抗胃肠细胞损伤、保护胃肠细胞的作用机理。

In this study, Mono-nuclear cells containing hematopoietic stem/progenitor cells were isolated from umbilical cord blood of normal full-term deliveries, healthy adult and heterocellular HPFH patient bone marrow by density gradient centrifugation. After simple purification and expansion in vitro, MNCs were induced to erythroid cell differentiation using different culture systems and cytokines including Epo, IL-3 and GM-CSF.

本研究首先利用密度梯度离心方法，从正常成人和异细胞型遗传性胎儿血红蛋白持续存在综合症家系患者的骨髓组织、健康足月正常分娩胎儿脐带血中分离得到了含有造血干／祖细胞的单个核细胞(Mono-Nuclear Cell，MNC)，进行初步纯化及体外扩增后，组合使用Epo、IL-3、GM-CSF等细胞因子，将造血干／祖细胞向红系方向进行诱导培养。

Once delivered to the heart, injected cells are difficult to distinguish from target tissue by MR in vivo.To specifically imaging injected cells in MR, the recent investigation generally using superparamagnetic iron oxid to label MSCs, which should enable serial tracking and quantification of MSC transplantation noninvasively by MR.

由于MR成像无法区分移植细胞和靶组织细胞，为使移植细胞能在MR上特异性显示，目前广泛使用超顺磁性氧化铁(superparamagnetic iron oxid， SPIO)作为负性标记物标记移植细胞，进行MR体外和活体内的成像研究。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐