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Results: The expression of NGF mRNA in aganglionic and hypoganglionic colon(2/9) was less than that in the proximal normal colon(8/9) and normal control.

结果: 无神经节细胞的巨结肠狭窄段和节细胞过少的肠组织与扩张段近端正常肠组织相比,其NGF mRNA表达水平降低,阳性率分别是2/9和8/9,肠神经元发育不良的病变肠组织NGF mRNA表达水平亦有下调趋势。

Results: The expression of NGF mRNA in aganglionic and hypoganglionic colon(2/9) was less than that in the proximal normal colon(8/9) and normal control. The IND specimen also showed decreased expression.

结果: 无神经节细胞的巨结肠狭窄段和节细胞过少的肠组织与扩张段近端正常肠组织相比,其NGF mRNA表达水平降低,阳性率分别是2/9和8/9,肠神经元发育不良的病变肠组织NGF mRNA表达水平亦有下调趋势。

The resultsshowed that malignant mesothelioma may be new histologic subtypes, including signet ringoidcell, small cell myxoid, myofibroblastic cell, lymphohistiocytoid, angioblastic cell and undifferen-tiated types.

结果发现,恶性间皮瘤新近的几种亚型有印戒样细胞型、小细胞型、粘液样型、肌纤维母细胞型、淋巴组织细胞样型、血管母细胞型和未分化型。

BACKGROUND: Under different induction conditions, bone marrow mesenchymal stem cells can differentiate into the mesodermal tissues such as osteoblasts, chondroblasts, muscle cells, adipocytes and so on.

背景:骨髓间充质干细胞在不同诱导条件下具有向中胚层组织细胞如成骨细胞、成软骨细胞、肌细胞、脂肪细胞等分化的能力。

METHODS:Nestin expression was detected in 33 cases of neuroepithelial tumors using the immunocytochemical staining. The Nestin positive and negative cells were isolated by magnetic activated cell sorting. Nestin positive cells were culutered, identified, and induced to differentiate. The expression of Nestin protein was detected in Nestin+ cells by RTPCR.

采用免疫组化法检测神经上皮肿瘤组织中Nestin的表达情况,免疫磁珠法分选肿瘤组织中的Nestin+细胞,悬浮细胞培养法进行Nestin+细胞的增殖、分化与鉴定,RTPCR法检测Nestin蛋白在其中的活性表达情况。

Brane, such as synoviocytes, macrophages, osteoclasts and TNF-αvv acts on different kinds of cell in synovial memchondrocytes, which can produce metalloproteinase,collagenase, stromelysin and so on, further induce pannus formation, joint inflammation, bone erosion and cartilage degradation.

TNF-α可作用于RA关节组织中的滑膜细胞、巨噬细胞、软骨细胞和破骨细胞,使这些细胞活化,产生金属蛋白酶、胶原酶、基膜溶解酶等,导致局部炎症反应和血管翳形成,进一步引起软骨破坏和骨侵蚀。

Tissue engineering is a multidisciplinary science merging with cell biology, material science, engineering and chemistry. Its basic idea is to expand a number of cells in vitro and seed them on a polysynthetic biodegradable polymer structure, and finally enable the organization of 3-dimmentional and functional tissues or organs.

组织工程技术是融合了细胞生物学、材料科学、工程学和化学的一门边缘学科,它的基本思想是用少量组织细胞经体外培养扩增后播种在可降解的生物支架材料上,再回植入体内形成有功能的组织或器官。

Signalling through CXCR4 mediates actin polymerization and pseudopodia formation in cells, and induces chemotactic and migration to target organs. In addition, CXCR4-SDF-1 axis can promote tumor angiogenesis and growth.

CXCR4在肿瘤组织中的表达明显高于正常组织,而肿瘤常见转移部位均为CXCR4的配体基质细胞衍生因子-1(stromal cell derived factor-1,SDF-1)表达丰富的器官,SDF-1与CXCR4结合后可使细胞肌动蛋白丝聚合,形成伪足,从而定向诱导肿瘤细胞迁移到特定的靶器官;此外,CXCR4与其配体SDF-1相互作用可以促进局部新生血管作用,利于肿瘤生长。

The findings of the newly identified goose paramyxovirus strain GPMV/HBexperimental infection were as follows: The challenge caused high morbidity and highmortality.The clinical signs included severe depression, decreased appetite or anorexia,white,yellow and green diarrhea, with neural symptoms;pathological changes showed thathaemorrhage and ulceration of intestine mucosa, necrosis of spleen and pancreas,andedema of liver and kidney, uratic deposition in kidney.Eosinophilic inclusion bodies werefound in the cytoplasm of pancreas and a large quantities of fiber protein were found inintestine. Lots of hemosidefin was found in some area of liver and kidney. A number ofT、B lymphocytes reduced sharply in spleen,lymph nodes in dead geese. Transmissionalelectron microscope showed that some cells had the morphological characteristics ofmitochondria swelling, morphological changes were condensation of nuclear chromatininto dense masses,followed by its marginating against the nuclear envelope, andespecially concentration of cytoplasm association with lots of lipid droplet.

人工感染雏鹅实验中,雏鹅临床表现为高发病率和高死亡率,食欲和饮水减少,拉白色、黄绿色稀粪,伴有神经症状;常规组织学观察,脾脏和胰腺肿大,有白色坏死斑点,肠道出血和坏死,肝脏肿大变性,肾脏肿大变性有尿酸盐沉着等;用特殊染色和组织化学方法首次对人工感染鹅副粘病毒的雏鹅的重要脏器进行研究,结果表明:胰腺中发现病毒包涵体,肠道中大量纤维素以及胶原纤维增生,肾脏、肺脏大量含铁血黄素沉着,免疫器官如脾脏和淋巴结中T、B淋巴细胞大量减少;电镜下多种细胞呈现线粒体水肿,多种实质细胞的染色质固缩,染色质边集,特别是细胞内容物如脂肪滴增多的病理变化特征。

The pattern of aerenchyma formation could originate by the combination of cortical cell autolysis and enlarged intercellular space. The process occurred in some stages: cortical cells stopped expansion and the intercellular space became larger at the initial stage. Cortical cells to collapse and autolysis were found with the disintegration of cell contents. After the evacuation of cell contents, cortical cells became shrinking and invaginated.

形成过程大体分为:皮层细胞生长停止,细胞间隙增大;皮层细胞衰老,并发生自溶,内含物解体;解体物逐渐撤走,皮层细胞开始收缩、内陷,当细胞内含物全部撤走,相邻细胞的残留细胞壁叠合即在两侧形成通气空腔;径向上相邻的皮层细胞逐步发生凹陷和细胞壁叠合,结合方形的细胞间隙一起构成通气组织。

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It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发,分析对称连杆曲线上鲍尔点的产生条件,提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品,年生产总值3000万美元,产品价廉物美、选料上乘、质量保证,深受国内外客户的青睐

The eˉtiology of hemospermia is complicate,but almost of hemospermia are benign.

血精的原因很,以良性病变为主。