组织形态学

Results After seven days of culture,some BMSCs appeared typical morphological neuronal traits.Cell bodies appeared refractile,conelike or spherical with long processes,NSE was expressed.Animals in group A and group B recovered their motor functions in a varing degree,the difference of BBB score was significant(P.05).Hematoxylin and eosin staining demonstrated that the lesion areas of the spinal cord in group A recovered better.

结果 诱导7 d后有部分细胞具备神经元样细胞形态，胞体呈锥形或圆形，有较长单极或多极的突起，有NSE阳性细胞表达；细胞移植后1～5周，A、B组动物运动功能均有不同程度恢复，但B组恢复较慢，BBB评分差异有统计学意义(P.05)；组织形态学观察示A组损伤脊髓恢复较好。

The Results displayed: DChanges of histological morphology in treating group is superior to the other two groups.(2Expression of BMP-2 at fracture region in treating group is obviously supeior to the other two groups(p.05) and advancely reach peak valuce at first weak.(3) transcriptional level of BMP-2 mRNA in treating group is obviously supeior to the other two groups(p.05) and samely advancely reach peak valuce at first weak.(4)In every period of fracture healing, the expression of BMP-2 and transcriptional level of BMP-2 mRNA appear dynamic change and begin to go up after fracture, moreover reached to peak value in two weaks, then go down gradually.

结果发现：(1)治疗组组织形态学检查明显优于其它二组；(2)治疗组骨折部位骨形态发生蛋白-2(BMP-2)的表达水平比其它二组明显提高(P＜0.05)，并在一周时提前达到高峰；(3)治疗组骨折部位骨形态发生蛋白-2(BMP-2)mRNA的转录水平比其它二组明显提高(P＜0.05)，同样在一周时提前达到高峰；(4)在骨折愈合的不同时期，BMP-2的表达及其mRNA的转录水平呈动态变化，即骨折后开始升高，2周左右达到高峰，以后逐渐下降。

The coeve to the plasma study of monoamine neurotransmitter in normal person and schozophreniac on four mian solar term in four seasons; tostudy the amount and the component of middle molecule substances in plasma on four main solar term in four seasons in nor- mal person and schizophreniac; to estabisht the experimental animal model of sehijorhrenia and the improve the measurement index; to study monoamine neurotransmitter value of brain in normal rats and experimental schizophrenia rats on four main soler terms; to study the amount and component of MMS in plasma of normal rats and experi- mental schizophrenia rats on four main solar terms, and to make The morphological study of the brain tissue in experimental schizophre- nix rats and normal rats.

健康人、精神分裂症患者一年四季血浆单胺类神经递质含量的研究。2。健康人、精神分裂症患者一年四季血浆中分子总量及组分的研究。3。精神分裂症动物模型的建立及评分标准的改进。4。正常大鼠、精神分裂症模型大鼠一年四季脑组织单胺类神经递质含量的研究。5。正常大鼠、精神分裂症模型大鼠一年四季血浆中分子总量及组分的研究。6。精神分裂症模型大鼠、正常大鼠脑组织形态学研究。

After spraying the fermentation supernatant of endophytic actinomycetes GKSHJA and PR1-8, the impact of the endophytic actinomycetes against Sphaerotheca fuliginea histomorphology were tested by the differential interference, and the enzyme activity of POD, SOD, PAL on cucumber leaf treated by spraying endophytic actinomycetes were tested by the spectrophotometer.

对喷施内生放线菌GKSHJA及PR1-8发酵上清液处理后采用微分干涉的方法观测生防菌对白粉菌的组织形态学影响，利用分光光度计测定喷施发酵液后黄瓜叶片内POD、SOD、PAL酶活变化。

Bases can be provided for forensic medicine authentication and medical prevention and treatment by observing big rats＇ tectological changes caused by the injuries from inhaling crude oil fume and gas fume.

观察大鼠吸入原油蒸气和汽油蒸气对器官损害的组织形态学变化，可为法医学鉴定和医学的防治提供依据。

Photodynamic therapy; liver neoplasms ; tectology ; mice

光动力疗法；肝肿瘤；组织形态学；小鼠

Animals, as material, were used to study the toxicity of outer substance and made sure the estrogen effect of BBP by whole animal experiment, and the chronic toxicity of BBP was studied, designed and valued through several dosages and different exposed time. The result showed that BBP could make testis, epididymis and prostate withdrawl. Tectology changes were observed in testis, epididymis and liver. Especially the atrophy and degeneration of seminiferous tubules, decrease of spermatogenic cell and the turbulence of Sertoli cell and spermatogenic cell of seminiferous epithelium were also observed. The linkage between cells vanished.

明确了BBP的雌激素效应，并分别用多剂量和不同染毒时间来研究、设计、评价BBP在体内的慢性毒性，结果表明：BBP能引起雄鼠睾丸、前列腺、附睾性腺的萎缩和肝脏肿大，改变睾丸、前列腺、肝脏的组织形态学，尤其引起睾丸曲细精管萎缩、变性，各级生精细胞减少，生精上皮内生精细胞和Sertoli细胞结构明显紊乱，细胞间连接结构消失等。

The therapeutic effect of HYJDT on glomerulosclerosis was observed by way of five aspects:(1) Effect on renal tissue morphology;(2) Effect on urine protein and blood creatinine and blood uria nitrogen ;(3) Effect on superoxide dismutase and malonydialdehyde in reual cortex;(4) Effect on matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-l (TIMP-1) in glomerulus;(5) Effect on MMP-9 mRNA and TIMP-lmRNA and type-1 plasminogen activator inhibitor (PAI-1) mRAN in glomerulus.

用药治疗12周取肾，HE、PAS染色，在光镜下观察肾组织形态学变化，并在透射电镜下观察肾小球超微结构的变化。用半自动生化分析仪检测肾皮质匀浆中SOD活力、MDA含量。用免疫组化技术检测肾小球中MMP-9、TIMP-1的蛋白表达，用原位杂交技术检测MMP-9mRNA、TIMP-lmRNA、PAI-lmRNA的基因表达。免疫组化和原位杂交结果，采用计算机图象分析系统测量各自的平均吸光度。所有的实验数据均用SAS6.12统计软件包进行统计学处理。

ObjectiveTo gain insight into the mechanism of iodine and thyroid hormone action in brain development. We have observed the difference of cerebellar morphology between iodine deficient dam rats and the normal ones and have tested whether congenital iodine deficiency could regulate immediate early gene proteins c -fos, c - jun and growth - associated protein - 43 ( GAP - 43) in pup cerebellums.

目的 本研究通过低碘饲料建立碘缺乏大鼠模型，观察子代大鼠在小脑发育期由于缺碘导致的小脑组织形态学改变及c-fos，c-jun蛋白和生长相关蛋白-43(GAP-43)表达变化，为探明碘缺乏影响小脑发育的致病机理提供实验依据。

The relationship between histomorphometric parameters of bone resorption and serum TRACP was evaluated in 14 chronically dialyzed patients and 6 healthy control subjects.

评估14 个慢性地肾透析患者和 6个健康的人作为临控，研究骨重吸收的组织形态学参数与血清 TRACP之间的相关性。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。