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Histone deacetylase 6(HDAC6) is microtubule and HSP90 associated protein, which control genetic transcription and change cellule motor ability by deacetylased microtubule and HSP90,and then participate tumorigenesis, growth, metabasis, and the production of tumor vessel.

研究方法: 1。应用激光捕获显微切割术联合逆转录-聚合酶链反应技术,检测36例行根治性切除的原发性肝细胞癌中心处非坏死癌组织及24例正常肝组织的HDAC6 mRNA在组织中的表达,并对HDAC6与肝癌发生发展过程中相关的临床病理因素间相关性进行研究。

The concentration of DOX in tumor and the apoptotic rate in cancer cell were all higher in DOX plus CWQ group than that in other groups.

结果 阿霉素和肠胃清单独给药均不能抑制肿瘤组织的生长,阿霉素与肠胃清联合能显著减少肿瘤组织的重量,增加肿瘤组织内的阿霉素浓度,诱导肿瘤细胞发生凋亡。

In the present experiment, the tender stems of Dracaena cambodiana were used as explants to establish a two-step tissue culture and regeneration system. The effects of types and concentrations of plant hormones on the induction of callus were studied. Based on these, the reactions of callus regeneration to different mutation-induced approaches (60Co irradiation, EMS and colchicines), the regeneration ability of the treated callus as well as the characters diversities (including the appearance traits and cytological observations) of the regeneration plants were investigated.

本试验以龙血树幼嫩茎段为材料,通过对龙血树幼嫩茎段两步培养法再生的研究,建立了龙血树幼嫩茎段离体再生体系,证明了愈伤组织的发生和激素种类与浓度的关系;并在此基础上研究了愈伤组织再生对不同人工诱变方法(60Co辐射、EMS、秋水仙素)的反应、被处理愈伤组织再生能力和再生植株性状多样性、以及再生植株不同生理角度的变异性,得到了2株变异株系。

After spores penetrated into the hemocoele, as the hyphae propagated and grew in the coelum, pathological changes occurred on all infected tissues and organs, including cuticle separating from epidermis, incompaet of fat body, disorganized digestive tract, crack in the muscle tissue and the disintegrated trachea tissue.

白僵菌侵入昆虫血腔后,随着菌丝在体腔内大量繁殖,受侵的各器官和组织均发生明显的病变,如皮细胞层和表皮分离、脂肪体松散、消化道被解体、肌肉组织出现裂缝、气管组织被解体破坏等。

They analyzed 45 of these new genes in both normal and cancerous tissues from the same patients and found that many of the genes were methylated specifically in the tumor samples.

他们分析了这些新基因中的45种,通过检测来自于同一个患者的正常组织和肿瘤组织发现,许多基因发生了甲基化,尤其是在肿瘤组织标本中。

Biocompatibility of tissue and material: All the materials used in operation were interstitial implant of titanium alloy. To the end of follow-up, there were no reaction of blood, immunization and tissue, no peplos formation or changes in cytoplasm, and no reaction of materials such as alloy corrosion and worn out.

材料与组织的生物相容性反应:术中所用材料均为钛合金体内植入物,与人体组织的生物相容性好,到随访结束时,无血液、免疫、组织等反应,无囊膜形成及细胞质的转变;亦无钛合金腐蚀、磨损等材料反应的发生。

We studied the optimum medium and hormone combination of callus induction from cotyledons, subculture of callus, shoot regeneration from callus, shoot-extension induction, root induction and identified the chromosome number of the plantlet. The results showed that: MS+2,4-D 2.0mg/L+KT 0.5mg/L, MS+2,4-D 2.5mg/L+KT 0.5mg/L, MS+2,4-D 0+KT 1.0mg/L, MS+KT 0.5 mg/L and basal MS medium. One plantlet among twenty two was determined as a tetraploidy based on the plant morphology, observation of the leaf stoma and chromosome number of the root, other two plantlets represented morphological variation.

结果表明,诱导章丘大葱子叶产生愈伤组织、愈伤组织的继代培养、愈伤组织芽分化、芽点的伸长及诱导生根的最佳培养基及激素配比分别为:MS+2,4-D 2.0mg/L+KT 0.5mg/L、MS+2,4-D 2.5mg/L+KT 0.5mg/L、MS+2,4-D 0+KT 1.0mg/L、MS+KT 0.5mg/L和MS基本培养基;试管苗经驯化移栽后,共有22株成活,成活率为92%,对成活的再生植株进行形态学、叶片气孔及根尖染色体鉴定表明,共有3株发生变异,其中2株为外部形态上的变异,而另一株为染色体的加倍变异。

Physics experiments on large scale uniform and non-uniform granular mixtures avalanche were carried out and the results proved that internal cause of SOC effect was most probably the structure characteristics of the system but not the size of granular or the scale of system.

为验证散粒体崩塌中的自组织临界现象是否是一种有限尺度效应,自组织临界现象的发生终究由系统的尺寸还是系统的组织原则来确定,进行了均匀和非均匀散粒体崩塌的实验。

Antibodies against col Ⅲ reacted strongly in the entire pterygial stroma. Conclusions Components of ECM are changed in the pterygium: the sub-epithelial connective tissues and vessels are more prominent in the pterygia than in normal conjunctiva tissues, and abnormal fibers are visible only in the deeper subepithelial connective tissues. This study documents the overexpression of LN and col Ⅲ. They may play roles in cellular adherency, migration and angiogenesis. Also this study documents the overexpression of MMP3 which may degrade ECM in the pathogenesis of the pterygium.

结论翼状胬肉组织中ECM的成分较正常球结膜发生改变,有大量的弹性纤维变性、胶原纤维增生及新生血管形成;col Ⅲ在翼状胬肉组织中表达增加,LN及胶原纤维可能对翼状胬肉中血管形成、细胞粘附和迁移及ECM重建起作用;MMP-3在翼状胬肉组织中表达增加,其对ECM成分的降解作用可能有助于翼状胬肉的形成和向角膜中央侵袭。

decrease or absence expression of pten and fhit protein play an important role in the genesis and development of gastric carcinoma; the two proteins can be used to judge carcinomatous biological behaviors and prognosis.

本研究采用免疫组织化学方法检测56例胃腺癌组织及10例正常组织中pten和fhit基因蛋白的表达情况,探讨其在胃腺癌发生、发展中的作用。

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And Pharaoh spoke to Joseph, saying, Your father and your brothers have come to you.

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嘿大乌鸦,个别谎言的事不要再-其所有的组织的谎言,在支持。