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Methods After succeeding in culturing rabbit retinal Müller cells and preparing AGEs-BSA in vitro, We observed the effects of AGEs on cultured rabbit retinal Müller cells in different interferent times (3d and 9d) by flow cytometry.

培养兔视网膜Müller细胞,体外制备AGEs及其对照物,实验分为牛血清白蛋白AGE作用3d、AGE-BSA作用9d、AGE-BSA对照3d、AGE-BSA对照9d、空白对照3d及空白对照9d

Patients in treatment group were treated with ultrasound-guided drainage, followed by intrapleural injection of 125, 000 IU urokinase (diluted by 50 ml normal saline), including 14 patients with pleural thickness〉 5 mm.

治疗40例分为A,B两,给予胸腔穿刺抽液引流并胸腔内注射尿激酶治疗,其中胸膜增厚〉5mm 14例为B;对照36例分为C,D两,给予反复胸腔穿刺抽水治疗,其中胸膜增厚〉5mm 13例为D;治疗和对照患者其他临床资料无差别,具有可比性;注药24h后抽液,B超定点测定首次注药前后的抽液量、胸膜厚度、纤维素分隔积分,差值结果作单因素卡方检验。

The DCs in gastric cancer groups with lymphangial invasion were lower than that of without lymphangial invasion.

有淋巴管侵犯的胃癌中树突状细胞浸润密度低于无淋巴管侵犯的胃癌(P=0.011)。p53表达阳性的胃癌树突状细胞浸润密度低于p53表达阴性的胃癌(P=0.032)。50例患者5年生存率中,树突状细胞高浸润(≥10.16/mm^2)明显好于树突状细胞低浸润(〈10.16/mm^2)(P=0.001)。

AngleⅢmalocclusion with TMD Compared with AngleⅢmalocclusion and thenormal group. In AngleⅢmalocclusion with TMD. there have greatly significant variations,transversely. During mandible open and close, the protrusion and reptrution in anydirections and medio movement in no-work sides,the range of condyle pathways of AngleⅢmalocclusion with TMD are bigger than the AngleⅢmalocclusion but shorterthan that of the normal group.

4在AngleⅢ类错伴TMD和对照AngleⅢ类错(牙合、正常相比:各项运动在Y轴上位移变异最大,在开闭口运动和前伸后退及侧方运动非工作侧中髁突运动最大位移范围基本上是正常>AngleⅢ类错伴TMD>AngleⅢ类错

The patients in the group A were given with mifepristone 10 mg once daily and nemestran 5 mg twice a week by mouth for 3 months,while the patients in the group B with mifepristone and placebo in the same dose and way as group A.The dimension of uterus and myoma was monitored respectively by B-mode ultrasound before and after treatment,the levels of estrogen,progesterone and hemoglobin as well as liver and renal functions were all measured at the same time.The side effects of drugs were assessed.Results:The results showed that the menoschesis occurred,and the distend and pain of hypogastric region and anemia were redressed in all patients during the treatment.

将绝经前有症状的子宫肌瘤患者100例随机分成两,A50例为小剂量米非司酮联合内美通,每天口服米非司酮10 mg,同时口服内美通5 mg,每周2次,连服3个月。B50例为米非司酮,每天口服米非司酮及安慰剂,剂量与服药方法同A;治疗前后B超测量子宫体积、肌瘤体积;检测用药前后雌、孕激素、血红蛋白和肝肾功能,观察服药后的不良反应。

He type of TGF β1 expression was related with lymph node metastasis and prognosis of patients. The positivity rate of TGF β1 expression only in mesenchyma in the group on lymph node metastasis was significantly lower than that in no lymph node metastasis, but the positivity rate of TGF β1 expression only in cytoplasma was higher. The prognosis of TGF β1 expression only in mesenchyma was better, but the prognosis of TGF β1 expression only in cytoplasma or both mesenchyma and cytoplasma was poor.

GF β1的阳性表达类型与肺癌的淋巴结转移及预后有关,淋巴结转移阳性TGF β1的单一间质阳性表达率显著低于淋巴结阴性,而单一胞浆阳性表达率高于淋巴结阴性;半年内死亡的TGF β1单一间质阳性表达率低于5年以上生存,而间质胞浆均阳性的表达率及单一胞浆阳性表达率则高于5年以上生存(P均<0.05)。

In this study, we investigate the heat-induced inhibition of drug-metabolizing enzyme activity in mice fed with freeze-dried, heated freeze-dried or half amount autolyzed freeze-dried Brussels sprouts powder. 0.5% ethoxyquin diet was fed to another group of mice as a positive control. The study mice, four per group, were fed a diet consisting of 20% Brussels sprouts for 7 days. Each group had its own pair-fed group. We found significantly greater inductions of glutathione S- transferase, quinine reductase, and phase Ⅱ drug-metabolizing enzyme activities in groups fed within freeze-dried and heated freeze-dried Brussels sprouts than their pair-fed groups. These findings indicate that intestinal microflora still can hydrolyze glucosinolates without plant myrosinase activity, though the alteration of cytochrome- P-450 1A (CYP1A, a phase Ⅰ drug-metabolizing enzyme) induction was only 1.4-fold.

本实验欲进一步探討加热处理之抱子甘蓝对phase Ⅰ与phase Ⅱ解毒酵素活性之影响差异,实验分三,抱子甘蓝(1)冷冻乾燥(glucosinolate未裂解)(2)加热冷冻乾燥(3)半量之裂解冷冻乾燥(glucosinolate已裂解),(4)and 0.5% ethoxyquin diet was used as a positive control以2%重量混合成饲料,餵以小白鼠(4只/)7天,结果发现,在第(2)小白鼠GST phase Ⅱ酵素)活性显著上升,显示在植物裂解酵素不存在之状况下,肠胃道之微生物仍可促进裂解反应,但由CYP1A活性增加不显著(仅1.4倍)看来,根据定义:单独phase Ⅱ酵素活性增加,为monofunctional induction/inducer,可加速致癌物之代谢。

All rats were killed twelve weeks later, the right kidneies were used for observing pathological change, and the expression of MCP-1 in nephridial tissue were detected by immunohistochemical method. Results (1) Change of morphology: the structure of renal tubule was normal in control group, most glomcruluses were segmented sclerosis in GS group, the renal lesions in valsartan group was minorer than this in GS group.

结果 (1)形态学改变:对照大鼠肾小管结构正常;肾小球硬化多数肾小球呈节段性硬化,许多肾小球及肾小管受累;缬沙坦治疗肾脏病变轻于肾小球硬化,且肾小球硬化指数明显低于肾小球硬化(P.01);(2)MCP-1的表达:对照肾小管中有少量MCP-1的表达,在肾小球内几乎不表达,在肾小球硬化和缬沙坦治疗肾小球及肾小管内表达皆强于正常对照(P.01)。

Results: Compared with IR group , XSOL could significantly decrease the cerebral water content, the cerebral index, the brain vascular permeability in rats of acute incomplete brain ischemia-reperfusion (P.01,P.05). Cerebral tissue morphology showed that neuronic damage of rats subjected to acute incomplete brain ischemia-reperfusion was ameliorated following administration of XSOL (2.4, 9.6g/kg). Compared with IR group , XSOL could significantly decrease the content of MDA and NO in brain tissue(P.01,P.05)and increase SOD,GSH-px activity. The levels of cerebral Glu,Asp were cut down(P.01,P.05). Conclusion: XSOL shows protective effects on cerebral ischemia-reperfusion.

结果:与缺血再灌注比较,XSOL大、小剂量可以显著降低急性不完全性脑缺血再灌注模型大鼠的脑含水量(P.01,P.05)、脑指数(P.01,P.05)、脑毛细血管通透性(P.01,P.05);光镜下脑织形态学显示各剂量可不同程度的减轻急性不完全性脑缺血再灌注大鼠脑织的神经元受损形态;与缺血再灌注比较,XSOL大、小剂量可以显著降低缺血再灌注大鼠脑织中的MDA的含量(P.01,P.05),升高SOD、GSH-Px在脑织中的活性(P.01,P.05);XSOL大、小剂量可显著降低脑织中NO的含量(P.01,P.05),降低脑织中Glu、Asp含量(P.01,P.05)。

Methods Ninety patients with diabetic nephropathy were randomly divided into two groups: control group and observative group. The routine treatment including administration of diabetic diet, blood glucose control and lossing blood pressure for 8 weeks. Ramipril was performed in control group for 8 weeks. Fasting blood glucose, total cholesterol, triglyceride, serum creatinine, urinary albumin excretion rate and plasma lipoprotein were detected and compared before treatment and 8 weeks later in two group.

90例DN患者随机分为两,治疗46例,对照44例,两患者均给予糖尿病饮食、控制血糖和降血压等常规治疗,对照给予雷米普利,观察在对照治疗的基础上给予氟伐他汀,两疗程均为8周;于治疗前和治疗8周后检测两空腹血糖、总胆固醇、甘油三脂、血肌酐、尿微量白蛋白排泄率和血浆脂蛋白,并进行比较。

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Lugalbanda was a god and shepherd king of Uruk where he was worshipped for over a thousand years.

Lugalbanda 是神和被崇拜了一千年多 Uruk古埃及喜克索王朝国王。

I am coming just now,' and went on perfuming himself with Hunut, then he came and sat.

我来只是现在,'歼灭战perfuming自己与胡努特,那麼,他来到和SAT 。

The shamrock is the symbol of Ireland and of St.

三叶草是爱尔兰和圣特里克节的标志同时它的寓意是带来幸运。3片心形叶子围绕着一根断茎,深绿色。