组

HLG of the 2nd grade acquired higher accuracy than LLG, and no significant difference was found either between HLG and MLG or between MLG and LLG; HLG of the 3rd grade had higher accuragy than both MLG and LLG, and no significant difference existed between MLG and LLG.

其中，在准确性方面，2年级高组高于低组，而高组与中组、中组与低组间均无显著差异，3年级的高组高于中组和低组，而中组与低组间无显著性差异。

In these portion,the article begins the study of tone sandhi from the point view of two-character phrases and three-character phrases,which is also the focus and difficult point as well.On the basis of substantial materials of Dingzhou dialect,the author elaborates its rules and principles of tone sandhi of the general phrases and those with light tones,and reiterative location.the author puts his views as follows: 1.The rules of tone sandhi of two- character phrase are simple and unitive. 2.The complex of the phrase with light tones lies in the combination of the first tone and light tone.In the case,there are two different pronunciations in Dingzhou dialect.The author guesses it is the coexist of ancient pronunciations and common spoken Chinese. 3.The tone sandhi of general three-character phrases on the basis of the rules of that of two- character phrases,using the grammar structure of the three-character phrases as the restricted conduction,which function jointly. 4.The rules of tone sandhi of three- character phrases with light tones are restricted only by that of the two- character phrases with light tones and thus are foreign to grammar structure. 5.The tone sandhi of the words with reiterative location has their own system.

这两章中，作者采用直接调查法，社会语言学方法分别从一般字组、含轻声字组和叠音词字组三个方面对定州方言连读变调进行详尽地描写，文章中既有对连读变调的共时性描写，也有对连读变调历时性推测，总的来讲笔者认为定州方言变调具有一定的系统性，主要表现在以下几个方面：两字组连读变调规律简单统一，含轻声字两字组内部规律较为复杂，但是具有很强的一致性；定州方言含轻声两字组变调的复杂性主要表现在阴平+轻声的组合中，在这种情况下，定州方言有两种读音方式，推测它是语音存古现象和普通话语音并存的结果；一般三字组连读变调以两字组连读变调规律为基础，以三字组的语法结构为制约条件，二者共同发生作用；轻声三字组变调规律只受轻声两字组变调规律的制约，与语法结构无关；叠音词的变调规律自成系统。

Result:As compared with the model group, the effect of small dose group and middle dose group of osteopractic total flavone on TBV% of shankbone increased significantly; the effect of small dose group and middle dose group of osteopractic total flavone on TRS% of shankbone reduced significantly and TFS%, AFS%, MAR, BFR of shankbone reduced obviously; the effect of middle dose group of osteopractic total flavone on OSW and mAR reduced obviously, the effect of small dose group of osteopractic total flavone on them had the tendency of reducing, but there was no statistical significance.

结果 ：对胫骨骨小梁体积百分比的影响，与模型组比较，骨碎补总黄酮小剂量组和中剂量组的TBV %明显增高；对胫骨骨小梁吸收表面百分比的影响，与模型组比较，骨碎补总黄酮小剂量组、中剂量组的TRS %显著降低；对胫骨骨小梁形成表面百分比，活性生成表面百分比，骨小梁矿化率和骨小梁骨生成率的影响，骨碎补总黄酮小剂量组、中剂量组的TFS %，AFS %，MAR ，BFR较模型组皆明显降低；对胫骨类骨质平均宽度和骨皮质矿化率的影响，骨碎补总黄酮中剂量组的OSW和mAR与模型组比较，明显降低；骨碎补总黄酮小剂量组与之相比，有下降的趋势，但无统计学意义。

12H treatment group compared with 12h model group: the density of light of HSP70 of the Gardenoside group is not different and which of it of TGFβ〓 increased with the model group; the density of light of the HSP70 of the Baicalin group in not different and which of the TGF-β〓 is no different with the model group, the density of HSP70 of the Concha Margatitifera Usta is not different and which of TGFβ〓 increased than the model group; the density of the HSP70 of the Cholic Acid group is no different and the density of TGF-β〓 increased than the model; the density of the light of HSP70 of the Hefang Group increased and which of TGF-β〓 increased than the model group.

合方治疗脑缺血12小时组缺血脑组织TGF-β1光密度值较缺血12小时模型组明显升高（p＜0.01）。大鼠局灶性脑缺血24小时模型组缺血脑组织TGF-β1光密度值含量较正常组明显增高（p＜0.01）。珍珠母治疗脑缺血24小时组缺血脑组织TGF-β1光密度值较缺血24小时模型组明显升高（p＜0.01）。胆酸治疗脑缺血24小时组缺血脑组织TGF-β1光密度值较缺血24小时模型组明显升高（p＜0.01）。栀子苷治疗脑缺血24小时组缺血脑组织TGF-β1光密度值较缺血24小时模型组无显著性差异（p＞0.05）。黄芩苷治疗脑缺血24小时组缺血脑组织TGF-β1光密度值较缺血24小时模型组明显升高（p＜0.01）。

This dissertation was focused on the research about the formation and evolution of NQB from the Late Triassic to the early middle Epoch of Jurassic Period, including integrated analyzing the characteristic of the key stratigraphic surfaces, the time of the key stratigraphy, regional rock straigraphy, biostratigraphy and chronostratigraphy, sedimentary system and depositional facies. On basis of these analysis, a tectonic evolution model have been established for NQB during from the Late Triassic to the early middle Epoch of Jurassic Period.1. After the systematic surface analysis about main stratigraphy units, we found that:(1) the bottom of Xiaochaka formation was comformity with the middle Triassic in the basin, and in the north margin it was deposited and overlapped on the different period stratigraphy before Triassic.(2) The top surface of Xiaochaka formation developed regionally karst and paleo-karst breccia, and was uncomformity with Nadigangri Formation, these things suggest that NQB in Xiaochaka depositing stage was developed from middle Triassic basin, and then an extensive regression occurred, the deposition was over and erosion come into being.(3) The lithologic assemblage, geochemistry, mixed fossils, and stratigraphy overlapping characteristic of Quemocuo Formation in early middle Jurassic indicted that the uncomformity surface was an extension-unconformity.2. Integrated analysis about stratigraphy division and correlation indicted that:(1) the paleontologic assemblage of Xiaochaka formation show its time was Carian -Norian stage of late Triassic. According to it was overlapped by late Triassic Nadigangri Formation, so Xiaochaka formation should be Carian - early Norian stage.(2) the SHRIMP Zircon U-Pb age of Nadigangri formation volcanic rocks wear vary form 216 to 205 Ma, so its time should be Norian, but maybe extended into Rhaetian Stage.(3) The age of its bottom volcanic rocks, the fossil assemblages of its middle and upper members and overlapped by lower Jurassic, indicted the age of Riganpeicuo Formation was Norian - Rhaetian stage. And the same time, the volcanic rocks geochemistry of Nadigangri and Riganpeicuo formation both reflected that they wear formed in rift tectonic settings. The lower lithologic and surface characteristic, fossil assemblages and its upper maybe was conformity with lower Jurassic, all reflected that the age of Tumengela Formation in Tumen area should be Norian - Rhaetian stage.

论文对晚三叠世—中侏罗世早期盆地的形成与演化开展了研究，包括关键地层界面特征分析、关键地层时代归属分析、区域岩石地层、生物地层和年代地层的综合对比分析、区域沉积体系与沉积相分析、岩相古地理分析，最终建立晚三叠世—中侏罗世早期羌塘盆沉积—构造动力演化模式。1、系统的对各地层单元的界面分析发现：(1)肖茶卡组底界在盆地内部与中三叠统整合关系，在盆地北缘为沉积超覆于不同时代的前三叠系之上：(2)肖茶卡组顶界面发育古岩溶角砾岩，与上覆那底岗日组为岩溶不整合接触，说明肖茶卡组沉积时期的羌塘盆地是在早中三叠世的盆地基础发展起来的，后期出现了广泛的海退事件，使盆地结束沉积并遭受风化剥蚀作用；(3)中侏罗统雀莫错组的岩性组合特征、岩石化学特征、古生物化石混积和地层的沉积超覆现象均表现出裂陷环境下形成的伸展不整合面的特征。2、综合地层划分与对比分析认为：(1)肖茶卡组古生物化石组合反映其时代为晚三叠世卡尼期—若利期，根据其上被上三叠统那底岗日组不整合覆盖，将其时代厘定为卡尼期—若利期早期；(2)那底岗日组火山岩SHRIMP锆石U-Pb年龄在216～205 Ma之间，其时代主要为若利期，可能包含有瑞替期：(3)日干配错组底部火山岩的年龄、中上部化石组合及其被下侏罗统整合覆盖，综合反映的时代为晚三叠世若利期—瑞替期，而且那底岗日组火山岩和日干配错组火山岩的地球化学成分分析反映两者均为引张构造背景下的产物；土门地区的土门各拉组的下部岩性及界面特征、化石组合和上部可能被下侏罗统整合覆盖，综合反映其时代为若利期—若利期。

Objective To examine the value of Edaravone in the treatment of vascular dementia through ethologic and pathologic changes induced by chronic cerebral ischemiaMethods Wistar rats were randomly divided into sham operated group,model group,edaravone group and duxil groupThe chronic cerebral hypoperfusion models were made by permanent bilateral occlusion of both common carotid arteriesThe memory ability and ultramicrostructure of brain tissue were observedResults The escape latencies in model group were more significantly prolonged than that in the other groups (P＜005)But there was no significant difference between edaravone and duxil groupAnd pathologic changes observed by electron microscope in nerve cell of edaravone group and duxil group and model group were fairly light than that in sham operated groupEdaravone group had increased mitochondrium and frontal membranous synaptic vesicle and more productive metabolic activityConclusions Edaravone can lessen injures of hippocampal neurons loss to improve the spatial learning and memory abilitiesAnd it is proved further that edaravone can treat VD

目的 观察依达拉奉对慢性缺血致血管性痴呆大鼠行为学及形态学的影响，探讨依达拉奉在治疗VD中的应用价值。方法实验分假手术组、模型组及都可喜对照组及依达拉奉治疗组，应用双侧颈总动脉结扎方法制备慢性脑缺血大鼠痴呆模型，观察各组大鼠的记忆功能及脑组织超微结构改变。结果缺血组水迷宫表现同对照组、都可喜组及依达拉奉组相比有显著差异(P＜005)，依达拉奉组与都可喜组相比未见显著差异。同时电镜观察结果也发现依达拉奉组及都可喜组与模型组及假手术组相比神经细胞病理改变较轻，且依达拉奉组线粒体及前膜突触小泡增多，代谢活动较都可喜组旺盛。结论依达拉奉可能通过减轻海马神经元的损伤来改善慢性脑缺血大鼠空间学习记忆障碍，证明依达拉奉对慢性缺血致VD大鼠具有治疗作用。

Methods: Animals were randomly classified into 5 groups: group A, gaster poured by physiological solution; group B, gaster poured by ethanol; group C, gaster poured by ethanol after hypophrenic vagectomy; group D, gaster poured by ethanol after big small splanchnicotomy; group E, gaster poured by ethanol after hypophrenic vagotomy and big small splanchnicotomy.

取30只成年雄性Wistar大鼠，随机分为5组，每组6只。A组：单纯生理盐水灌胃组；B组：单纯乙醇灌胃组；C组：膈下迷走神经切断乙醇灌胃组；D组：内脏大、小神经切断乙醇灌胃组；E组：膈下迷走神经和内脏大、小神经均切断乙醇灌胃组。

Methods: Animals were randomly classified into 5 groups:gaster-poured by physiological solution; gaster-poured by ethanol; gaster-poured by ethanol after hypophrenic vagotomy; gaster-poured by ethanol after big-small splanchnicotomy; gaster-poured by ethanol after hypophrenic vagotomy and big-small splanchni-cotomy.

动物被随机分为5组，每组10只。A组：单纯生理盐水灌胃组；B组：单纯乙醇灌胃组；C组：膈下迷走神经切断乙醇灌胃组；D组：内脏大、小神经切断乙醇灌胃组；E组：膈下迷走神经和内脏大、小神经均切断乙醇灌胃组。

To test the hypothesis, neontal rat cadiomyocytes Treat with heat shock(HS,42℃,2h) to induce the expression of HSP70,then teated with 0.5mmol/L H2O2. We first found H2O2 can reduced cadiomyocytes apoptosis and HSP70 only over-expression in the HS group, other two group only express HSP70 a little in the test of expression of HSP70.Then we tested the concentration of Ca2+, the [Ca2+ ] of CON was 192.224+6.654, the [Ca2+ ] of H2O2 group was 290.6918+8.922and the [Ca2+]of HS group was 214.2633+4.484.To further determine how HSP70 repaired the Ca2+ homestasis, we measured calcium transient of each group.

实验中应用MTT和流式细胞技术检测细胞的凋亡，发现损伤组的存活率明显低于其他2组，热休克组(Heat shock group，HS group)细胞存活率略低于正常组细胞；免疫组化结果表明只有在HS组才检测到阳性反应，即是HSP70的表达，其他2组均为弱阳性结果；应用离子成像技术对细胞内钙离子浓度进行测定，发现损伤组290.6918+8.922明显高于正常组192.224+6.654和HS组214.2633+4.484，HS组细胞内的钙离子浓度略高于正常组；为了进一步探讨HSP70对于ROS引起的心肌凋亡过程中钙离子的调控机制，又对各组的心肌细胞进行了钙瞬变的测定。

Perfusion in the right parietal lobe in group2 was significantly lower than in group1 (P.01).（2）Average perfusions were higher in the right temporal and parietal lobes than in the left in all 3 groups.（3）Gray matter volumes were significantly smaller in group3 than in group2 (P.05); total cerebral spinal fluidsvolumes were significantly larger in group3 than in group1 and group2（P.05）; right hippocampus volumes were significantly smaller in group3 than in group1 （P.05）. Conclusions Age-related change of cerebral blood perfusions in the healthy elderly over 65 years is characterized with hypoperfusion in the right parietal.

结果（1）经方差分析，第2组和第3组脑组织几乎所有部位的灌注均低于第1组，其中第2组右顶叶灌注的放射性计数比值为0.87±0.18，低于第1组（RAR=0.98±0.17；P.01）；（2）经配对t检验，除第2组的双侧顶叶外，3组颞叶和顶叶的灌注均为右侧高于左侧（P.01和0.05）；（3）经方差分析，第3组的灰质体积占颅内容积的百分比［（47.59±1.26）%］小于第2组［（49.43±1.30）%］，总脑脊液体积占颅内容积的百分比［（14.61±3.16）%］大于第1组［（12.41±0.73）%］和第2组［（11.94±1.27）%］，右侧海马体积［（2.04±0.23）cm3］小于第1组［（2.27±0.20）cm3］，P均。05。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。