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However, a steady input of evidence for the transcription-independent function of p53 in apoptosis has been accumulating recently. Although a detailed mechanism has not yet been determined, recent data have revealed that upon an apoptotic stimulus, p53 translocates into mitochondria to interact directly with Bcl-2 or Bcl-xL to displace and activate proapoptotic Bax signaling.

但是,还有研究证明p53也通过转录非依赖的形式来调节细胞凋亡,尽管这个作用的机制还没有被详细的阐明,但是最近的研究报道说明了,p53可以直接转移定位到线粒体上,与Bcl-2或者Bcl-xl结合后,从而使Bax游离下来并活化。

In order to establish the simple extraction method of wheat mitochondrial DNA, this study investigated the effects of triturating material, exacting mitochondria and exacting and purifying mtDNA from yellow seedling of wheat, respectively.

为了建立小麦线粒体DNA快速提取体系,以小麦黄化苗为材料,分别研究了材料的研磨、线粗体的抽提和mtDNA的提取及纯化过程中众因素的影响。

Effect of estrogen on dopamine release evoked by electric stimulation of central amygdaloid nucleus. Acta Physiol Sin, 2001, 53(3):170~174.

而且在线粒体呼吸链中,氧接受一个电子O·〖TX-*82, O·〖TX-*82在过氧化物歧化酶的作用下可生成H2O2,而O·〖TX-*82本身可促进Fe3+由其铁结合蛋白上的释放,从而加速了OH·的生成[13],机体氧化与抗氧化机制平衡的破坏同样加速了这一反应。

In Genus Culter, genetic distance within species is obviously lower than that between species. And in the phylogenetic trees, all individuals of each species formed a clade. Then the conculsion was that mitochondrial CO1 gene was a good marker in Culter DNA barcoding. The conclusion was the same when the research group turned to Subfamily Cultrinae.

对鲌属物种的DNA条形码研究而言,其种间遗传距离显著地大于种内遗传距离,并且同一物种的不同个体均形成高支持率的单系,说明在鲌属类群中线粒体CO1基因是一个有效的DNA条形码标准基因。

Cybrid cells can be studied in th...

融合细胞具有一致的核背景,可以消除核基因的作用,因而有助于判断mtDNA突变的致病作用及机制和线粒体缺陷的致病作用及机制。

The cells inhibited in eucaryotes by chloramphenicol are those that are multiplying rapidly, such as blood-forming cells of the bonemarrow, where new mitochondria are being synthesized at a rapid rate.

氯霉素影响真核细胞中那些繁殖得快的,比如骨髓中的造血细胞,在这里新的线粒体正以很高的速率生成。

A phylogenetic tree was reconstructed based on the partial sequences of 16S rDNA and COⅠgenes in eight commercial flatfishes. The parameters of pairwise genetic distance among these flatfishes were calculated.

进一步利用线粒体DNA的16S rDNA、COⅠ基因的部分序列对8种重要海水养殖鱼类的系统进化分析,计算了其种间的遗传距离。

The morphologic al changes of the livers were examined under light microscope and electron m icroscope.

结果保存0~120h的兔肝,其组织结构基本正常;保存到144h兔肝,电镜下见肝细胞的线粒体出现轻度肿胀和嵴少;随着保存时间的延长肝细胞出现明显的细胞变性。

Alcohol, the most common cause, is a hepatotoxin that interferes with mitochondrial and microsomal function in hepatocytes , leading to an accumulation of lipid.

酒精,是最常见的原因,酒精所产生的毒素干扰了肝细胞线粒体和微粒体的功能,从而导致了大量脂肪酸的堆积。

Drugs of beta-hydroxy-beta-methylglutaryl coenzyme A reductase inhibitors family are usually used as a very effective lipid-lowering preparations but they simultaneously block biosynthesis of both cholesterol and ubiquinone Q10, which is an intermediate electron carrier in the mitochondrial respiratory chain. It is known that reduced form of ubiquinone Q10 acts in the human LDL as very effective natural antioxidant.

HMG-CoA还原酶抑制剂是非常有效的降脂药物,但它同时抑制胆固醇和辅酶Q的生物合成,而其中辅酶Q是线粒体呼吸链中的中间电子载体,其还原形式在人LDL中是有效的天然抗氧化剂。

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The concept of equivalent rotationally rigidity is offered and the formula of rotationally rigidity is obtained.

主要做了如下几个方面的工作:对伸臂位于顶部的单层框架—筒体模型进行分析,提出了等效转动约束的概念和转动约束刚度的表达式。

Male cats normally do not need aftercare with the exception of the night after the anesthetic.

男猫通常不需要善后除了晚上的麻醉。

Its advantage is that it can be used in smaller units.

其优点在于可以在较小的单位中应用。