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If the EDD provide an indication of Ca2+ localization,the results suggest that theophylline may release Ca2+ associated with subsurface cisternae, plasma membrane, mitochondria and subsurface cisternae may be a primarily functional Ca2+ storage site in the ganglion cell.

本文根据实验结果讨论了茶碱可能促使钙离子从交感神经元的上述部位中释放出来,并认为质膜、亚表面池和线粒体是细胞内钙离子的贮存部位,而亚表面池可能是主要的贮存释放部位。

Savolainen thought that there were at least six founders existing in the origin center, because clade A structure was too complicated to decide how many founders were contained in it.

另外,在Savolainen等人的研究中,由于支系A的结构非常复杂,因而无法判断其中包含了几个建群者,所以在他们的结论中只是笼统地给出,现代家犬的起源—线粒体DNA的研究起源中心的母系建群者不少于6个。

Treatment of hepatocytes with clofibrate caused a significant increase in intracellular and mitochondrial ROS.

用氯贝丁酯处理过的肝细胞及线粒体内自由基显著增加。

Clofibrate may impair mitochondrial function, stimulates formation of ROS, and eventually contributes to cell death.

安妥明通过影响线粒体功能,从而诱发过多的自由基产生,最终导致细胞死亡。

Conversion of the different forms of these coenzymes is the main reason for these two enzymes performing the particular function and giving the particular phenotype.

线粒体NADPH的主要供应者Pos5p可以使NAD向NADP转变,细胞质NADPH的主要供应者Zwf1p可以使NADP+向NADPH转变,对不同形式的辅酶的转变是它们行驶特定功能及产生特定表型的重要原因。

The energy released by the Krebs cycle is transferred via the reduced coenzymes NADH2 and FADH2 to an ELCTRON-TRANSPORT CHAIN embedded in the inner mitochondrial membrane.

这些在卡尔文循环中释放的能量被还原性的辅酶 NADH2和 FADH2转移到线粒体内膜的电子传递链上。

In Genus Culter, genetic distance within species is obviously lower than that between species. And in the phylogenetic trees, all individuals of each species formed a clade. Then the conculsion was that mitochondrial CO1 gene was a good marker in Culter DNA barcoding. The conclusion was the same when the research group turned to Subfamily Cultrinae.

对鲌属物种的DNA条形码研究而言,其种间遗传距离显著地大于种内遗传距离,并且同一物种的不同个体均形成高支持率的单系,说明在鲌属类群中线粒体CO1基因是一个有效的DNA条形码标准基因。

With the development of transmitochondrial technique, the methods of establishing cybrid cellular model are various.

随着转线粒体技术的发展,制备该细胞模型的方法也多种多样。

Cybrid cells can be studied in th...

融合细胞具有一致的核背景,可以消除核基因的作用,因而有助于判断mtDNA突变的致病作用及机制和线粒体缺陷的致病作用及机制。

Furthermore, the very significant/nearly identical increase in the ratio of doubling times in dmdm medium in the presence/absence of high concentration of paromomycin was observed in symptomatic or asymptomatic cybrid cell lines carrying the c1494t mutation as compared with the average rate in control cell lines.

结果 来自听力下降者的融合细胞系的线粒体dna标记速率分别比对照组4名成员的12个融合细胞系下降了38%和43%,这一缺陷显然造成了携带c1494t突变的融合细胞(不论来自听力正常者还是来自听力下降者)的细胞总体呼吸率下降,或苹果酸/谷氨酸、琥珀酸/3-磷酸甘油及tmpd/抗坏血酸所始动的呼吸率下降。

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