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MtDNA mutation result in insulin deficiency by tricarboxylic acid cycle obstruction.

此外,细胞线粒体的异质性决定其突变的致病效应不同。

MtDNA mutation result in insulin deficiency by tricarboxylic acid cycle obstruction.

线粒体基因突变可通过三羧酸循环障碍导致β细胞分泌胰岛素不足。

Pyruvate dehydrogenase kinases (PDKs 1-4) can regulate the activity of mitochondrial pyruvate dehydrogenase complex to catalyse the oxidative decarboxylation of pyruvate, and then to link glycolysis to the tricarboxylic acid cycle and ATP production.

丙酮酸脱氢酶激酶具有能够调节线粒体丙酮酸脱氢酶复合体催化丙酮酸脱羧氧化的活性,并进一步将糖酵解与三羧酸循环以及ATP的生成联系在一起。

It will also damage the biomembrane, for example, the damage ofmitochondria will decrease the tricarboxylic acid cycle and oxidative phosphorylation,so the synthesis of ATP will be decresed.

如造成线粒体膜损伤,可减少三羧酸循环和氧化磷酸化,ATP合成障碍;对膜蛋白如酶、受体、离子通道等造成损伤,降低运动能力。

In order to analyse the relationship between several Trichinella isolates from different areas in China,we amplified the COI gene from these isolates and obtained their sequences.

为了了解我国几个不同地区旋毛虫之间的种属关系,我们对这些地区的旋毛虫进行了线粒体细胞色素氧化酶亚单位I基因的扩增,并得到了正确的COI基因。

Domestic and overseas entomologist has showed that different molecular marker methods for molecular identification of Trichogramma species. However, each of molecular marker methods previously has own deficiency, and molecular marker genes used in Trichogramma species identification almost is ribosomal DNA, study about mitochomadrial DNA in Trichogramma spp. is infrequent.

近年来,随着分子生物技术的发展,国内外研究者曾用不同分子标记方法来进行赤眼蜂蜂种的分子鉴别,然而每种分子标记都有自己的不足,且赤眼蜂分子鉴定中用于序列分析的标记基因基本上为核糖体核糖核酸基因,而有关线粒体DNA的研究却鲜有报道。

Mitochondrial 16S rRNA gene fragments were amplified from dolphins Tursiops truncatus,Sousa chinensis and Steno bredanensis using PCR technique.

采用聚合酶链式反应技术扩增瓶鼻海豚、中华白海豚和糙齿海豚的线粒体DNA16S rRNA基因,获得了大约600bp的片段。

Mitochondrial 16S rRNA gene fragments were amplified from dolphins. Tursiops truncatus , Sousa chinensis and Steno bredanensis using PCR technique. The PCR products were about 600 bp and were directly sequenced subsequently.

摘 要:采用聚合酶链式反应技术扩增瓶鼻海豚、中华白海豚和糙齿海豚的线粒体DNA 16S rRNA基因,获得了大约600 bp的片段。

Mammalian mitochondria contain about 1100 proteins, nearly 300 of which are uncharacterized.

哺乳动物的线粒体内含有约1100个蛋白质,其中有近300个没有明显特征。

Terminal oxidative inhibitors, such as KCN, Salicylhydroxamic acid , antimycin A and NaN〓, can cut off electron transport chains of cytochrome pathway and alternative pathway, marked decreased BADH protein levels. Oxidative phosphorylation uncoupler 2, 4-dinitrophenol had a similar negative effect on BADH gene expression, and exogenous ATP and ADP increased the BADH levels. These results, in conjunction with the terminal oxidation results, indicated that ATP could be a critical component in BADH gene expression.

2.2 末端氧化抑制剂KCN、SHAM、抗霉素A和NaN〓能打断呼吸链,阻断电子传递,使BADH蛋白的表达量明显降低,说明末端氧化同样参与BADH基因表达的调节:末端氧化影响基因表达的实质就是ATP的影响,线粒体磷酸化解偶联剂DNP明显降低BADH蛋白的含量,而外源的ATP和ADP对BADH基因表达的正效应作用最大。

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However, as the name(read-only memory)implies, CD disks cannot be written onorchanged in any way.

然而,正如其名字所指出的那样,CD盘不能写,也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

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A single payment file can be uploaded from an ERP system to effect all pan-China RMB payments and overseas payments in all currencies.

付款指令文件可从您的 ERP 系统上传到我们的电子银行系统来只是国内及对海外各种币种付款。