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The result shows why mitochondrial suppression is so important to tumours: when they are unsuppressed, the tumour they are in stops growing.

为何线粒体抑制对肿瘤如此重要从试验结果可见一斑:当线粒体未受到抑制时,线粒体所在的肿瘤就会停止生长。

Ultrastructural examination revealed swelling and disorganization of cristae in myocardial mitochondria in traumatic group, and only slight swelling of mitochondria was found in intervention group.

电镜观察显示,创伤组心肌线粒体肿胀、嵴断裂,可见较大的线粒体,而干预组线粒体仅轻度肿胀。

If the mitochondrial analysis is correct, then because mitochondrial Eve represents the root of the mitochondrial family tree, she must have predated the exodus and lived in Africa.

如果线粒体分析是准确的,那么由于线粒体夏娃便是代表线粒体族谱的根。她一定事先就随着大批人迁移,最后定居在非洲。

Alberta, in Canada, are testing a drug called dichloroacetate that suppresses the Warburg effect and reactivates the

为何线粒体抑制对肿瘤如此重要从试验结果可见一斑:当线粒体未受到抑制时,线粒体

They are synthesized in the cytoplasm, then translocated to mitochondrial and located in the inner membrane by specific transport mechanism.

该家族成员由细胞质合成,经特定的转运机制,运输入线粒体,并定位于线粒体内膜,负责小分子物质跨线粒体内膜的转运。

Upon induction of apoptosis by diverse stimuli, Bax undergoes a conformational change and translocates to mitochondria, where it oligomerizes and forms pores that allow the release of cytochrome c and other cytotoxic foctors.

在被不同刺激诱导后,Bax的构象发生改变并转移到线粒体上。在线粒体膜上,它形成低聚物并使线粒体膜形成孔,使细胞色素c和其它细胞毒性因子可以排出。

The injured gill cells had a different ultrastructure, with endoplasmic reticulum dilated and vesiculated, mitochondrial cristaes partially disintegrated, gill fibre cuticles denatured and dropped. The ultrastructural damages to hepatopancreatic cells were characterized by the decrease of microvilli, swelling and breaking up of mitochondria, expansion of endoplasmic reticulum, disruption and vacuolization of nucleus, tumefaction of nuclear membrane and increase of lipid droplets. As for the toxicological changes of myocardial cells, the mitochondria were swelling, having a lot of vacuolus and disintegrating, while the myofibrils were irregular with endoplasmic reticulum dissolved.

鳃细胞的损害表现为鳃丝水肿,细胞器溶解,角质层变薄,线粒体、内质网的肿胀、解体;肝胰脏细胞的主要损害特征为肝管微绒毛减少,线粒体水肿解体,内质网扩张,细胞核空泡化,核膜水肿和脂肪滴增加;心脏细胞的毒理变化为线粒体内嵴肿胀、瓦解,肌原纤维不规则,内质网溶解。

In this experiment,nad4 and cox1 genetic variation of cestodes were firstly studied.Genetic variation and DNA polymorphism of mitochondria were carried out from mitochondrial gene.So the effective genetic markers were found which studied molecular taxonomy and Phylogenetic relationship of cestodes.This study have filled in the blank space of research that was related to China\'s cestodes mitochondrial genome research.

本试验首次对绦虫nad4和cox1基因的遗传变异情况进行研究,从线粒体基因的角度,开展绦虫线粒体遗传变异和DNA多态性方面的研究,找到了研究绦虫分子分类学、种群遗传关系有效的遗传标记,填补了我国寄生绦虫线粒体全基因组相关研究的空白。

The mtDNA defects and the role of mitochondrial lesion in the pathogenesis of RTT were investigated using mtDNA transfer by cybrid technique.

采用PCR,PCR-RFLP及DNA测序方法筛查MeCP2基因突变,采用融合细胞技术进行线粒体的转移实验探讨线粒体DNA缺陷以及线粒体损伤在RTT发病中的作用。

In addition, we studied the distribution of mitochondria in metaphase Ⅱ rabbit oocytes, zygotes and early embryos by two active mitochondria dyes and revealed the change of active mitochondria during early development of rabbit embryos. We also found that the distribution of microfilaments and microtubules have similar patterns to that of active mitochondria, which is an important basis for further development of animal cloning study using the recipient oocytes derived from rabbit.

此外,我们应用两种线粒体荧光染料研究了日本大耳白兔体内成熟卵母细胞、正常交配后收集的受精卵及早期体外发育胚胎的活性线粒体的位置变化,首次揭示了兔早期胚胎中活性线粒体的变化特征及其与微丝微管变化的相关性,为进一步开展以兔卵母细胞作为核移植受体的动物克隆研究打下了重要的基础。

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