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Cognition disturbance and allolalia were the chief clinical manifestations. The imageology showed that the impairment involved occipital lobe and temporal lobe most. 17 cases presented red-ragged-fibres and parking lot-like ultrastructure in 3 cases. Brain biopsy showed layerage structure. There were 15 of them carried mtDNA A3243G mutation. Conclusions MELAS Syndrome usually involved central nerve system and skeletal muscle.

主要临床表现为认知功能障碍及言语障碍,头颅影像学检查示枕叶、颞叶脑回受累为主。18例行肌肉病理检查显示17例存在破碎样红纤维,3例行肌肉电镜检查发现线粒体堆积呈停车场样排列,3例脑活检示病变皮层组织呈分层样改变,15例发现mtDNA A3243G点突变。

Less common associations are with hypoparathyroidism, pseudo-hypoparathyroidism, Fahr's familial idiopathic cerebral calcificatinon, birth anoxia, carbon monoxide intoxication, lead poisoning, Tuberous Sclerosis, Cockaynes syndrome, postinfectious encephalomyelitis, AIDS, radiation therapy, methotrexate, mitochondrial disease (Kearns-Sayer), and, as in the case shown here, Down's syndrome.

脑钙质沉着与以下疾病有着非普通联系:甲状旁腺机能减退,假甲状旁腺机能减退,Fahr's家族特发性脑钙化,出生缺氧症,一氧化氮中毒,铅中毒,结节硬化症,科克因综合征,流行性感染后脑脊髓炎,艾滋病,放疗,氨甲喋呤,线粒体病,以及Down's综合症。

The changes of DNA content and mitochondrial transmembrane potential in LEC were detected by flow cytometry.

将培养的牛LEC分别与160 μg/mL Ele和20 μg/mL Cur在CO2培养箱中共同孵育8,16,24,48,72 h,通过透射电子显微镜观察LEC超微结构;采用流式细胞术测定LEC的DNA含量及线粒体跨膜电位。

Genetic divergence and phylogenetic relationships among 6 leopard cat populations from 3 subspecies in China were analyzed through Random Amplified Polymorphic DNA and mitochondrial DNA sequencing methods.

本文通过随机扩增多态性DNA技术和线粒体DNA序列分析技术,对豹猫3个亚种6个群体64个个体进行了遗传多样性和系统发育分析。

Bengalensis is higher, on average 2.27%. The intersubspecies ranges from 2.73% to 6.590/c, and averages 4.0 1%. The analyses of nuclear DNA and mitochondrial DNA data are almost consistent, and V indicate considerablly abundant genetic diversity in leopard cat.

豹猫线粒体DNA控制区的序列差异在个体间为0.68%~6.59%,平均为3.14%,北方群体内差异较小,平均为1.71%,南方三个群体内的DNA序列差异平均为2.27%,而豹猫的北方亚种和指名亚种间差异较大在2.73%~6.59%之间,平均为4.01%。

The are obvious biases in the both codon and amino acid usage in Lepidoptera species mitochondrial PCGs.NNU and NNA are the most frequently used codons.

鳞翅目昆虫的线粒体基因组中蛋白编码基因密码子的使用和氨基酸使用都有极强的偏向性,其中NNU和NNA密码子的使用频率相当的高。

To further studied the phyligenetic relationships of lepidopteran insects,a larger number of insect orders and mitogenome are required.

因此关于鳞翅目的系统发育关系,有待于基于更多样本量的线粒体基因组数据进行深入探讨。

Based on the combined dataset of nucleotide and amino acid sequences of 13 protein coding genes,using the maximum likelihood and Bayesian inference methods to reconstruct the phylogenetic relationship of fifteen species of lepidopteran insects,The resulst showed the same topologies and supported a close relationship between the Geometroidea,Noctuoidea and Bombycoidea.This result deviates from the traditional view.

基于线粒体基因组13个蛋白质编码基因的核苷酸序列及氨基酸序列的联合数据集构建了15种鳞翅目昆虫的系统树,采用BI和ML分析方法建树,所得拓扑结构类似,都显示蚕蛾总科,尺蠖蛾总科和夜蛾总科关系较近,结果与前人研究的结果不完全一致。

Other challenges include anaemia, mitochondrial toxicity, drug-drug interactions and leucopenia.

其他的挑战包括贫血、线粒体毒性、药物-药物的相互作用和白细胞减少症。

The mtDNA Legacy of the Levantine Early Upper Palaeolithic in Africa - Back-migrations of ancient Asian populations through the Levant contributed to the peopling of northern and eastern Africa.

线粒体上游旧石器时代早期遗留的东方非洲-背古亚洲迁徙种群通过运动会为peopling北部和东部非洲。

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