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线粒体

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Results as bellows: AtSIRT1 was located in Mitochondrial as hSIRT4 of human, and maybe take part in respiration and electron transformation chain, AtSIRT2 was located in nucleolus as hSIRT6 of human, maybe play important role in extend lifespan;mutation in AtSIRT1 leaded to cotyledon of plant turn to yellow and caused short life span. Mutation in AtSIRT2 could make the color of leaf turn to purple and accumulate a lot of anthocyanin;Sirtinol, a inhibitor of SIRT which did not cause the same model of the mutation of AtSIRT1 and AtSIRT2 indicated that the mechanism of Sirtinol was different from other organism;the structure of AtSIRT1 and AtSIRT2 were similar to other known Sir2, which indicated that they maybe have the same function;AtSIRT2 was overexpressed and its activity was detected.

结果表明,1,拟南芥AtSIRT1与人的同源蛋白hSIRT4相同,定位于线粒体,可能参与呼吸作用和电子传递,SIRT2与人的同源蛋白hSIRT6相同,定位于细胞核,可能同它的功能类似,在延缓衰老及调节细胞寿命方面起作用。2,AtSIRT1突变,可引起幼苗和植株的子叶变黄和早衰;AtSIRT2突变,可引起叶片发紫,沉积大量花青素。3,SIRT蛋白的抑制剂Sirtinol不能表型模写AtSIRT1和AtSIRT2突变体,说明Sirtinol在拟南芥中的作用机制不同于其他生物。4,AtSIRT1和AtSIRT2蛋白质结构预测表明与已知的Sir2蛋白相似,揭示其功能的相似性。5,在大肠杆菌中过量表达了其中一个基因(AtSIRT2),可体外检测其酶学活性,进一步证明其功能。

The number of midochondria was changed in combination with the change of the expression of chaperone.

在这些过程中,伴随着分子伴侣表达量的高低变化,细胞线粒体数量也会发生相应的变化。

Chloromycetin had positive effect on BADH gene expression, and the effect might be due to inhibit repressor generation in mitochondria and activate transcription factor of BADH gene.

应用氯霉素的实验表明氯霉素对BADH基因表达为正效应,提出了可能是抑制了线粒体中的阻遏蛋白的产生使BADH基因表达去阻遏。

In this paper,we reviewed the research development on interactions of nuclear and mitochondrial genes,including human disease and aging,apoptosis,chloromycetin resistance,ANT,MnSOD and mtTFA.

本文就线粒体核质基因互作在人类疾病、衰老、细胞凋亡、氯霉素抗性、ANT、MnSOD、mtTFA的研究进展进行了综述。

Affected by heavy metal ions, the number of mitochondria and chloroplast reduced on different levels.

5受重金属离子的影响,线粒体和叶绿体的数目在不同程度上减少。

An efficient antioxidant network is essential for the maintenance of cell functions,particularly in the context of mitochondrial and chloroplast metabolism.

一个有效的抗氧化剂网络系统对于维持细胞的功能是很必要的,尤其是在叶绿体和线粒体的新陈代谢中。

Plant mitochondria often have sequences that appear to have been acquires from chloroplast DNA.

植物线粒体经常有看来是获取从叶绿体DNA 的序列。

Once proteins have been translated, they can also be delivered to other organelles in the cell, such as the mitochondria and the chloroplast.

一旦蛋白质已被翻译,也可以传送到其他器官的细胞,如线粒体和叶绿体。

The multiplication and origin of mitochondrion and chloroplast.

线粒体和叶绿体的增殖与起源。

Results showed that TDI induced toxic action on spermatogenic cell,while the chondriosome was its target within the length and concentrations.

结果表明:在本实验染毒时间和染毒剂量范围内,TD I对雄性的生殖毒性主要表现为对各级生精细胞均有一定的毒性作用,作用的靶点是细胞内的线粒体;TD I通过影响各种酶的活性,干扰了睾丸组织的有氧代谢和无氧供能,抑制了细胞对能量的利用,损伤了各级生精细胞,导致生精上皮不可逆的损害,从而造成了其对雄性生殖系统的损伤;TD I对雄性生殖细胞的核酸代谢以及DNA合成有一定影响。

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