线粒体

The drug isometamidium chloride, is an effective therapeutic and prophylactic agent. It lyses the parasite, and it also accumulates in its mitochondrion to significantly disrupts aerobic respiration by causing lesions in the organelle.

氯化氮氨菲啶是防治隐鞭虫病的有效药物，它通过溶解虫体而杀灭寄生虫，也可在线粒体中富集，显著影响有氧呼吸的顺利进行并造成线粒体的损伤。

In heathlty cells, AIF protein is normally confined to mitochondrial intermembrane space. However, after apoptosis is induced, AIF protein can be released from mitochondria and translocates into nucleus leading by its nuclear localization signal.

正常情况下，AIF蛋白定位于细胞线粒体膜间隙，当有凋亡信号刺激时，AIF分子从线粒体释放到细胞浆，再通过其核定位信号转位到细胞核中，直接引起染色体凝集和DNA的大片段(~50kb)断裂，导致细胞凋亡。

Endo G is a mitochondrial DNA enzyme which translocates to nucleus after releasing from mitochondrion and cuts chromatin DNA into nucleosome fragments in a caspase-independent manner.

Endo G是一种线粒体DNA酶，当其从线粒体释放出来之后，可以转位到细胞核，并且以caspase非依赖性方式将染色质DNA剪切为核小体碎片。

The result indicated that after the yellow seedlings of wheat was triturated by the high speed tissue triturating machine, high purity mitochondria could be exacted by density gradient centrifugation, and then the mitochondria was ruptured by the 5% SDS and protease K, and the protein was wiped off by organic liquid, pure mtDNA could be extracted.

结果表明，经高速组织匀浆捣碎机研磨小麦黄花苗，简易的密度梯度离心技术快速抽提大黄的高纯度的线粒体，5% SDS和蛋白酶K裂解线粒体及有机溶剂抽提去除蛋白质可获得纯度较高的mtDNA。

Results After 3 months of kidney radiation by 15 Gy of Cs137 γ-rays, the changes with kidney shrank, Bowman's capsules straitened or disappeared, glomerular swelled, some epithelia denaturalized or died were observed. Mitochondria tumefied and the cristae shortened, lessened and disordered. Urine β2-MP rose evidently. It was lowered significantly the renal 25-OH-D-1α-hydroxylase activity and its mRNA expression. The dry and ash weight, BMD of femur and lumbar were significantly reduced, volume and width of bone trabecula were distinctly decreased and the space increased in model group. The Pyd / Cr increased and ALP decreased as well.

结果 15Gy 137Cs-γ射线肾局部照射3个月后肾脏体积缩小，肾小球肿大，Bowman氏囊囊腔狭窄甚至消失，部分肾小管上皮细胞变性、坏死，线粒体肿胀，体积增大，线粒体嵴变短、减少、排列紊乱；尿β2-MP显著增加；肾1α羟化酶活性及1α羟化酶mRNA基因表达量明显下降；肾辐射组股骨干重、灰重、腰椎和股骨BMD明显降低；骨小梁体积和骨小梁宽度减少，骨小梁间距增加，MAR减小；腰椎压缩和股骨三点弯最大载荷明显降低，Pyd / Cr值明显增加，ALP显著降低。

It uncouples oxidative phosphorylation but, unlike the aflatoxins, does not induce mitochondrial swelling or hinder Ca2+-induced swelling of mitochondria.

它解开氧化磷酸化但不像黄曲霉毒素类，不能诱导线粒体肿胀或阻止Ca2+诱导的线粒体肿胀。

The recent researches show that effect of 'mild uncoupling' of respiratory chain is involved in mitochondrial anti-oxidation event.

目前的研究表明，线粒体呼吸链&温和解偶联&机制也参与了线粒体内的抗氧化防御过程。

Ultrastructure observation revealed that the nuclei became deformed, nucleolus disintegrated and chromatin condensed, the thylakoids of chloroplast swelled, the chloroplast membrane disrupted, cristae of mitochondria disappeared and mitochondria vesiculated.

电镜观察发现，Cd(上标 2+)处理下，细胞核变形，核仁解体，染色质凝集；类囊体片层膨胀，叶绿体双层膜破裂；线粒体中嵴突减少或消失，线粒体空泡化。

For example, she found that the phytochemicals interfere with the orderly operations of mitochondria, the miniature energy-producing power plants inside cells. Without energy, cells die.

例如，她发现这些化学物质可以影响那些已衰老的细胞的线粒体，失去了线粒体为细胞提供能量的正常功能，这些细胞就会死亡。

The oxygen consumption with the substrates of succinate in RTT significantly decreased by 34％ as compared with that in control. RTT cybrids produced more oxygen radicals than that of control cybrids as measured by anti-cyano-respiration that reflects the production of oxygen free radicals in mitochondrial respiratory chain. RTT cybrid cell lines demonstrated an increased sensitivity to 〓-induced apoptosis as compared to control cybrids.

以琥珀酸为底物时患儿组融合细胞线粒体呼吸氧耗率显著降低，较正常对照组降低34％；患儿融合细胞线粒体呼吸链氧自由基水平增高，对〓刺激的凋亡易感性增高。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。