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Thirty-six rats ,weighing(250±10)g, were randomly divided into normal group, experimental group and control group.Orthodontical devices were put between the upper incisor teeth and dens molaris in both experimental group and control group.The corrective force was adjusted to 60g.Salvia miltiorrhiza combination was implanted to each rat in the experimental group every day.The animals of both experimental group and control group were killed at 7,14 and 21 days.The upper dens malarias and periodontal tissue slices were observed under the light microscope and transmission electro microscope,and the X-ray dental films were taken and measured with digitization dental scanning apparatus and its software.

以36只体重(250±10)g的雄性大鼠为样本,随机分为正常组、实验组和对照组,设定不同浓度丹参复合膜,以同体对照方式在正常组进行体内植入实验,在2周内观察不同浓度丹参的牙周组织诱导作用,寻找最佳应用浓度;在实验组和对照组的上切牙与磨牙之间隙安装正畸装置,建立大鼠磨牙移动实验模型,矫治力的大小为60g;实验组每日每只体内植入丹参复合生物膜,两组动物于正畸加力7、14、21d,分三批处死;处死后立即切取双侧上颌磨牙及牙周组织制取标本,制片透射电镜和光镜观察;拍摄X线牙片,用数字化牙科扫描仪及软件对其进行测量分析。

The corrective force was adjusted to 60g.Salvia miltiorrhiza combination was implanted to each rat in the experimental group every day.The animals of both experimental group and control group were killed at 7,14 and 21 days.The upper dens malarias and periodontal tissue slices were observed under the light microscope and transmission electro microscope,and the X-ray dental films were taken and measured with digitization dental scanning apparatus and its software.Result:The most fitting concentration of combined biological membrane was 0.80g;the speed of the remodeling of the periodontal tissue at the compression side in the experimental group was faster than that of the control group.

以36只体重(250±10)g的雄性大鼠为样本,随机分为正常组、实验组和对照组,设定不同浓度丹参复合膜,以同体对照方式在正常组进行体内植入实验,在2周内观察不同浓度丹参的牙周组织诱导作用,寻找最佳应用浓度;在实验组和对照组的上切牙与磨牙之间隙安装正畸装置,建立大鼠磨牙移动实验模型,矫治力的大小为60g;实验组每日每只体内植入丹参复合生物膜,两组动物于正畸加力7、14、21d,分三批处死;处死后立即切取双侧上颌磨牙及牙周组织制取标本,制片透射电镜和光镜观察;拍摄X线牙片,用数字化牙科扫描仪及软件对其进行测量分析。

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