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There is up-regulation of striatum D2 receptors in lesioned side in experimental hemi-parkinsonism which show good correlation with rotation behavior induced by Apomorphine, and coincided with the pathological findings.

大鼠偏侧PD模型患侧纹状体D2受体出现上调反应,这种上调反应与APO诱导的行为学改变呈良好的相关性,与病理组织学改变相符合。

After autoxidation, the toxic metabolite 1-methyl-4-phenylpyridinium is formed and cause damage to the dopaminergic neurons.

对黑质-纹状体多巴胺神经传导途径有高度专一性的伤害,能引发与人类巴金森氏症相似的颤抖、肌肉僵直及起始运动困难等症状。

Parkinson's disease is a common and disabling disorder of movement owing to dopaminergic denervation of the striatum.

帕金森氏病是一种常见的由于纹状体除多巴胺能神经支配的运动异常疾病。

It is caused by the degeneration of nigro-striatum dopaminergic neuron resulting in the reduction of dopamine and the hyperfunction of acetylcholine.

帕金森病(Parkinson's disease,PD)为神经系统变性疾病,主要的病理改变是黑质纹状体通路的多巴胺能神经元变性,导致多巴胺减少和乙酰胆碱系统功能亢进。

Parkinson's disease is a common neurodegenerative disease, which mainly affect the old age, characterized by tremor, muscle rigidity, bradykinesia and postural instability. It is caused by the degeneration of nigro-striatum dopaminergic neuron resulting in the reduction of dopamine and the hyperfunction of acetylcholine.

帕金森病(Parkinson's disease,PD)为神经系统变性疾病,主要的病理改变是黑质纹状体通路的多巴胺能神经元变性,导致多巴胺减少和乙酰胆碱系统功能亢进。

Brains were removed cut on a freezing microtome at a thickness of 30 m. Immunofluorescence technique was used to detect BrdU and Nestin, NSE and GFAP were detected by immunohistochemistry.

取10一巧代的细胞,BrdU标记后在立体定向下通过细针移植入成年鼠的纹状体和大脑皮层,分别于移植后1周和6周取脑行冰冻切片,行BrdU和Nestin免疫荧光检测,以及NSE和GFAP免疫组化染色。

AIM To construct the three-dimensional (3-D) stereotactic morphology of the corpus striatum, marginal division and globus pallidus in an adult rat brain.

目的 建立和了解成年大鼠纹状体、边缘区和苍白球在脑中的立体形态和相互关系。

By the computer 3D technique, a 3-D stereotactic morphology of the corpus striatum, marginal division and globus pallidus was thus reconstructed.

建立了大鼠脑纹状体、边缘区和苍白球的三维立体结构。

The protection of VOA on brain may relate to the release of monoami neurotransmitters in corpus striatum increased, oxidative stress alleviated and neuronal apoptosis in substantia nigra reduced.

VOA的脑保护作用可能与其增加脑内纹状体单胺类神经递质释放、减轻氧化应激反应以及减少黑质致密部神经元凋亡有关。

METHODS:① Model group: The rats were made into models of Parkinson disease with damaged corpus striatum by injecting 6-hydroxydopamine (6-OHDA, 12 μg), which was dissolved in 5 μL normal saline containing 2 g/L ascorbic acid, slowly into caudal putamen.

①模型组:将6-羟基多巴(12 μg溶于5μL含2 g/L抗坏血酸的生理盐水中)缓慢注入尾壳核,建立纹状体毁损帕金森病大鼠模型,不干预。

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Finally, according to market conditions and market products this article paper analyzes the trends in the development of camera technology, and designs a color night vision camera.

最后根据市场情况和市面上产品的情况分析了摄像机技术的发展趋势,并设计了一款彩色夜视摄像机。

Only person height weeds and the fierce looks stone idles were there.

只有半人深的荒草和龇牙咧嘴的神像。

This dramatic range, steeper than the Himalayas, is the upturned rim of the eastern edge of Tibet, a plateau that has risen to 5 km in response to the slow but un stoppable collision of India with Asia that began about 55 million years ago and which continues unabated today.

这一引人注目的地域范围,比喜马拉雅山更加陡峭,是处于西藏东部边缘的朝上翻的边框地带。响应启始于约5500万年前的、缓慢的但却不可阻挡的印度与亚洲地壳板块碰撞,高原已上升至五千米,这种碰撞持续至今,毫无衰退。