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In the developing telencephalon, Nolz-1 is preferentially expressed in the subventricular zone and mantle zone , but not in the ventricular zone of LGE/striatum.

在发育端脑中, Nolz-1优先表现在LGE/纹状体的subventricular zone 及 mantle zone,而不表现在ventricular zone区域。

Mehtods Thirty male SpragueDawley rats were randomly divided into acute stress,chronic stress and control group(each n=10),acute and chronic stress models were made with forced swimming and empty bottle stimulation separately,and frequency of getting into central grille, detention time , outer grille numbers,modifying numbers and dejecture grain number were observed with openfield experimental box;expressions of neuropeptide Y and adenylcyclase in prefrontal lobe cortex, hippocampus CA3,striatum of the groups were observed using the immunohistochemistry method and correlation analyses conducted.

将30只雄性SD大鼠随机分为急性应激组、慢性应激组和正常对照组,每组10只,用强迫游泳和空瓶刺激分别制作急性和慢性应激模型,采用开野实验箱观察各组大鼠进入中央格次数、停留时间、外周格子数、修饰次数、粪便粒数;采用免疫组织化学方法检测各组大鼠神经肽Y、腺苷酸环化酶在前额叶皮质,海马CA3区,纹状体的表达水平,并进行相关分析。

In the most caudal extent of the striatum, there was also a dense band of CGRP-positive fibers in the lateral border of the caudate putamen and the direction of the fibers was also dorsoventral. There are some transverse CGRP-positive fibers connecting the MrD and Cpu.

CGRP免疫阳性纤维分布越靠纹状体尾,则纤维越密集,且阳性带越宽;(2)在纹状体的最尾侧,除边缘区外,尾壳核的外侧缘也出现一条致密的阳性纤维带,与边缘区走向一致。

The CGRP-positive fibers ran dorsoventrally in the MrD and formed a dense band. The CGRP-positive fibers were more densely and widely distributed in the caudal part of the MrD.

结果发现:(1)CGRP免疫阳性纤维在纹状体内存在于纹状体的中部和尾侧,位于尾壳核和苍白球之间,即相当于纹状体边缘区的部位,形成一条明显的背腹方向走行的带状。

Based on the results, it has found that six distinct layers can be identified from lateral to medial in the olfactory bulbs, and the adults have more cells than the subadults. Ventricles of the adults take up larger vacuity, have richer choroids plexus, and primordial pallium and primordial hippocampus of them are more developed than the subadults, in which the primordial piriform is well-developed. Ventral to the primordial hippocampus, there is a septal area which can not be divided into medial and lateral parts in both adults and subadults, nor there is lateral limiting sulcus to separate the primordial piriform and the corpus striatum, but only in the subadults, a medial limiting sulcus can be clearly identified to separate the primordial hippocampus and the septal area. Besides, the corpus striatum of Onychodactylus fischeri is paleostriatum. The cell group that located at two sides of the third ventricle is amygdale, and shape and size of neurons within the telencephalon are poorly differentiation.

结果表明:爪鲵嗅球内细胞从外到内大致可分为6层结构,亚成体的细胞数量少于成体;成体爪鲵的侧脑室所占空间较大,脉络丛更为丰富,原始大脑皮层和原始海马都比亚成体发达,后者大脑内原始梨状区较为发达;隔区位于原始海马的下方,成体和亚成体都没有外侧隔核和内侧隔核之分,也没有外侧界沟作为原始梨状区和纹状体的分界,而在亚成体的侧脑室壁有内侧界沟区分原始海马和隔区,成体则没有;此外,爪鲵的纹状体属于古纹状体,杏仁核是位于第三脑室两侧的两个细胞团,端脑内细胞形态和大小分化较为单一。

The differentiation of dopaminergic neurons of substantial nigra completes under the induction of striatum and its function realizes by synapse with striatal neurons.

黑质中多巴胺能神经元的分化是在纹状体的诱导下完成的,其功能活动也是通过与纹状体神经元建立的突触连接而实现的。

Results TAEP can significantly decrease the contents of monoamine neurotransmitter in the straite body and the bordering area of rat forebrain, increase the contents of neutral and acidic metabolites in the straite body, and increase the contents of 5-HIAA and HVA of the monoamines in the bordering area of rat forebrain.

结果 TAEP对大鼠纹状体的单胺类神经递质的含量具有显著的降低作用,同时升高纹状体单胺类递质中性及酸性代谢产物的含量;对大鼠前脑边缘区的单胺类递质具有显著的降低作用,同时显著升高边缘区单胺代谢物5—羟吲哚乙酸(5—HIAA),高香草酸的含量。

Researchers have found that college students with relatively large striatums learned how to play a challenging video game faster than their small-striatum peers.

研究者发现,拥有相对较大纹状体的大学生能比有小纹状体的学生更快的学会玩一款有难度的游戏。

Those with larger striatums picked up the game faster, for example, and they shifted playing strategies more effectively than did students with smaller striatums.

那些拥有大纹状体的学生能比别人更快上手,比如他们能比小纹状体的学生更有效的切换战略。

Then NSCs were grafted into the striatums of PD rats with GDNF. Tyrosine Hydroxylase-positive cells were gradually increased at 30d after transplantation in the striatum of PD rats.

采用原代培养胚胎14.5天的胎鼠腹侧中脑NSCs,单独或经GDNF预处理后移植入PD模型大鼠的纹状体,观察NSCs在纹状体的分化情况,以及PD模型大鼠旋转行为的变化。

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