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Parkinson's disease is a common and disabling disorder of movement owing to dopaminergic denervation of the striatum.

帕金森氏病是一种常见的由于纹状体除多巴胺能神经支配的运动异常疾病。

Objective To explore the possibility of basic fibroblast growth factor and epidermal growth factor combined with st-riatal conditioned medium promoting the directional differentiation of rat bone marrow mesenchymal stem cells into dopaminergic neurons.

目的 探讨联合应用碱性成纤维细胞生长因子、表皮生长因子和纹状体条件培养液定向诱导大鼠骨髓间充质干细胞分化为多巴胺能神经元的可能性。

Objective: This paper aims to verify the curative effect that Jiusuyu cure the acute alcoholism disease by counting the changes of ebriety time, ebriety rate, sober-up time death rate, and discuss the effect of neurotransmitter and oxidative damage on acute alcoholism mice in brain tissue by examining the changes of SOD, MDA, DA, 5-HT, AchE in btain tissue.

目的:本研究旨在通过观察急性酒精中毒小鼠模型醉酒时间、醒酒时间、醉酒率、死亡率来验证酒速愈的药效,并通过检测脑组织中超氧化物歧化酶、丙二醛,纹状体多巴胺、5-羟色胺(5-HT)和海马胆碱脂酶指标的变化探讨该药对急性酒精中毒小鼠脑神经递质和氧化损伤的影响。

Investigations in vivo and in vitro have elucidated the following: IL-2 and IL-2R have been detected in the brain; IL-2 promotes survival and neurite extension of cultured neurons, stimulates oligodendrocyte proliferation and maturation, affects the hypothalamic-pituitary function and produces behavioral and electrocorticogram spectrum changes.

研究表明IL-2在脑中主要存在于海马、下丘脑、小脑、前额皮层、纹状体、膈以及蓝斑等脑区。

It is caused by the degeneration of nigro-striatum dopaminergic neuron resulting in the reduction of dopamine and the hyperfunction of acetylcholine.

帕金森病(Parkinson's disease,PD)为神经系统变性疾病,主要的病理改变是黑质纹状体通路的多巴胺能神经元变性,导致多巴胺减少和乙酰胆碱系统功能亢进。

Parkinson's disease is a common neurodegenerative disease, which mainly affect the old age, characterized by tremor, muscle rigidity, bradykinesia and postural instability. It is caused by the degeneration of nigro-striatum dopaminergic neuron resulting in the reduction of dopamine and the hyperfunction of acetylcholine.

帕金森病(Parkinson's disease,PD)为神经系统变性疾病,主要的病理改变是黑质纹状体通路的多巴胺能神经元变性,导致多巴胺减少和乙酰胆碱系统功能亢进。

Interestingly, at E13.5, strong Foxp2-expressing differentiated striatal neurons were detected in region adjacent to SVZ, rather than in lateral part of MZ as in the control littermate.

有趣地,在胚胎期第13.5天,高量表现Foxp2的已分化纹状体神经元在近SVZ区被侦测到,而不是像同胎对照小鼠在MZ区外侧被侦测到。

Fetal neural tissues, such as ventral mesencephalon, striatum, and Schwann cells, were investigated for neurodegenerative diseases or spinal cord injury.

胚胎神经组织如中脑、纹状体和雪旺细胞在神经退行性疾病和脊髓损伤中的作用也有研究。

The system of dopaminergic neurons that projects from the tegmentum of the mesencephalon to various telencephalic sites, including frontal cortex, striatum

多巴胺能核的系统从中脑的大脑脚盖发射到不同的终脑位置,包括脑额叶皮质、纹状体、隔膜、扣带脑皮层、杏仁孔和阿肯柏氏核。

Brains were removed cut on a freezing microtome at a thickness of 30 m. Immunofluorescence technique was used to detect BrdU and Nestin, NSE and GFAP were detected by immunohistochemistry.

取10一巧代的细胞,BrdU标记后在立体定向下通过细针移植入成年鼠的纹状体和大脑皮层,分别于移植后1周和6周取脑行冰冻切片,行BrdU和Nestin免疫荧光检测,以及NSE和GFAP免疫组化染色。

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