级联调节

Ultimately, vulnerable groups of neurons atrophy and die in a process that may involve excitotoxicity (overstimulation of neurotransmitter receptors on neuronal surface membranes), collapse of calcium homeostasis, inflammation, and depletion of energy and growth factors. A form of apolipoprotein E, apoE4, contributes to the abnormal accumulation of A and tau, but probably also damages mitochondria and the cellular cytoskeleton. A , tau, apoE and -synuclein interact with many other molecules and modulate diverse signalling cascades that regulate neuronal activity and survival.

最后，易感神经元会萎缩直至死亡，原因可能有兴奋性中毒（神经递质对神经元表面受体的过度刺激引起），钙稳态失衡，炎症反应，能量和生长因子的耗尽。apoE4的产生可导致A肽和tau蛋白的异常聚合，可能也损害线粒体和细胞骨架。A肽、tau蛋白、apoE和突触核蛋白可与很多分子反应，也可调节不同信号级联反应，这些级联反应对于维持神经元活动性和生存性意义重大。

Pombe mutants; and the recombination of pREP3X-HA-spm1, pREP3X-HA-pmp1 and pREP3 X-HA-mid2 possesses an expressed activity. Chapter 4 Edelfosine Affect the Phosphatization of MAPK Spm1 of S.

第四章依地福新影响粟酒裂殖酵母MAP激酶Spm1的磷酸化蛋白激酶级联调节胞质和胞核对细胞外刺激的应答。

In the SD rats with acute liver failure, the different levels of serum endotoxin are existed and the level of cell factors diversification inflammation progressional reactions can be induced, and SMD can regulate the level of cell factors to treat the disease.

急性肝衰竭状态下，可存在不同程度的内毒素血症，并引起细胞因子水平变化的炎症级联反应，生脉散通过调节细胞因子水平起到治疗作用。

The cloning, sequencing, homological blasting and Northern blotting results of 5 desiccation-induced cDNAs and 3 phosphate induced cDNAs implied that signal transduction induced by desiccation, regulatory gene cascades and functional genes such as G protein, protein kinase, VP3and MAD3-like genes might be involved in dehydration in the resurrection plant Boea hygrometrica.

对其中5个脱水特异诱导表达的cDNA（包括可能与复苏能力有关的cDNA）和3个磷酸盐处理诱导表达的cDNA进行克隆测序、同源性探测和Northern杂交检测表明，牛耳草脱水过程中诱导表达的基因可能涉及到脱水胁迫的信号转导、调节基因的级联作用（VP3，MAD3样基因等）、结构基因产物调节细胞结构在脱水胁迫中的稳定性等。

This invention relates to a cascade multiple zero-type matrix rectifier, in which, a general input filter is connected between a net and a step-down transformer to get sine-wave input current, the step-down transformer includes n secondary windings with Yn spliced mid lines, the phase of all the three-phase windings is the same, the rectifier array is arrayed in a 1 row x n lines by n zero-matrix rectifier units, each line of which is connected with the seconday winding of the step-down transfornmer, and the outputs of the rectifier units are serial orderly to form a DC output, the general controller is responsible for regulating work of the entire system and connected with the branch controllers by signal cables to control the work of the rectifier units in the array.

本发明涉及一种级联多重化零式矩阵整流器，总输入滤波器连接在电网与降压变压器之间，滤波得到正弦波形的输入电流，降压变压器有n个Yn接带中性线的次级绕组，所有三相绕组相位相同，整流器阵列由n个零式矩阵整流器单元排成1列×n行的阵列，阵列中每一行与降压变压器的一个次级绕组对应连接，阵列中整流器单元的输出依次串联，形成一路直流输出，总控制器负责控制调节整个系统的工作，并通过信号电缆与各个分控制器联络，控制整流器阵列中每个整流器单元的工作。本发明由低压小功率的变换器串联得到幅值可调的高压直流电源，同时在电网侧得到位移为零的输入电流，具有网侧四象限运行能力等优点，适用于中高压直流供电领域。

In this reiew, we focus on the differentiation of mesenchymal stem cells (including those of the myoblastic, osteoblastic, chondroblastic, neural, and apidoblastic lineages) and the possible, if unexpected, biological significance of MMPs in its regulation.

在此综述中，我们着重分析间充质干细胞的分化和间充质干细胞的分化的调节过程中MMPs可能起到的生物学作用。MMP系统已经被证明涉及若干的分化效应，这显示基质金属蛋白酶调节蛋白水解酶蛋白水解级联的增殖和分化效应。

Activation of PKC is one of key link in the cell signal transduction passway, which mediated cellular signals, participated expression of genes, and influenced cell cycles.

蛋白激酶C是信号转导通路中发挥关键作用的蛋白激酶之一，做为信号分子，它的活化是一系列细胞级联信号传导途径的关键环节，既介导多种细胞信息的传递，又参与调节基因的表达与功能，影响细胞周期，对肿瘤细胞的生长、分化、增殖与凋亡起调节作用。

The invention discloses an optical-fiber all-optical code converter, comprising a temperature control circuit as well as optical-fiber Mach-Zed interferometer, heat sink, semiconductor refrigerator, thermosensitive resistor and radiator, where the interferometer is composed of two cascaded 3dB couplers on the heat sink, the relation between length difference delta L of two arms of the interferometer and generated delay time difference delta T is that delta L=c.delta T/n, where c is light velocity in vacuum and n is refractive index of optical fiber; the thermosensitive resistor is used to detect temperature of interferometer, the temperature control circuit is used to compare feedback voltage of the thermosenstive resistor with a given voltage to regulate working current of the semiconductor refrigerator, and the semiconductor refrigerator refrigerates or heat two arms of the interferometer by the heat sink.

本发明公开了一种光纤型全光码型转换器，它包括温控电路和位于密封盒内的光纤型马赫-泽德干涉仪、导热热沉、半导体制冷器、热敏电阻以及散热片；干涉仪由位于导热热沉上的二个3dB耦合器级联而成，两臂的长度差ΔL与产生的延时差ΔT之间的关系为ΔL＝c。ΔT/n，c为真空中光速，n为光纤折射率；热敏电阻用于对干涉仪的温度进行探测，温控电路用于比较热敏电阻反馈的探测电压和设定电压，对半导体制冷器的工作电流进行调节，半导体制冷器通过导热热沉对干涉仪两臂同时进行制冷或加热。

The company has independently developed, development, production of the products have six series, more than 400 varieties, including: wire and cable series: high-temperature compensation wire, control cables, fire-retardant cables, anti-corrosion cable, power cable, 6 ~ 110KV crosslinked power cables, computer cables, silicon rubber cables, high temperature cables, fire-resistant cables, low smoke low halogen, low smoke zero halogen cables, such as the main cable tray; Temperature Instrument Series: ITS900 in line with the International Temperature Scale and IEC standards A, B-grade Thermocouple , Explosion-proof Temperature Transmitter integration, intelligent all-input temperature transmitter; Pressure / Differential Pressure Meter Series: general pressure gauges, precision pressure gauges, pressure / differential pressure switch, the general stress / Differential Pressure Transmitter, 1151 , 3051 smart capacitive pressure / differential pressure transmitter; Level Instrument Series: glass / glass level gauge, quartz glass tube liquid level, the electric-contact level gauge, magnetic liquid level transmitter, magnetic liquid level switch, input-type hydrostatic liquid level transmitter, liquid level transmitter float electricity, etc.; Flow Meters Series: All English Intelligent Vortex Flowmeter, Turbine Flowmeter; Display Instrument Series: Intelligent Control LED digital display device, Intelligent LCD screen controlled device, Guangzhu instructions figures, such as conditioning Alarm.

公司自主研制、开发、生产的产品主要有六大系列、400多个品种，其中有：电线电缆系列：高温补偿导线、控制电缆、阻燃电缆、防腐电缆、电力电缆、6～110KV交联电力电缆、计算机电缆、硅橡胶电缆、高温电缆、耐火电缆、低烟低卤、低烟无卤电缆主电缆桥架等；温度仪表系列：符合ITS900国际温标和IEC标准的A、B级热电偶，防爆型一体化温度变送器、智能全输入温度变送器；压力/差压仪表系列：一般压力表、精密压力表、压力/差压开关、普通压力/差压变送器，1151、3051智能电容式压力/差压变送器；液位仪表系列：玻璃管/玻璃板液位计、石英玻璃管液位计、电接点液位计、磁性液位变送器、磁性液位开关、投入式静压液位变送器、电浮筒液位变送器等；流量仪表系列：全中文智能涡街流量计、涡轮流量计；显示仪表系列：智能LED数字显示调节控制仪、智能LCD界面显示调节控制仪、光柱指示数字显示调节报警仪等。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。