纤维骨瘤

Methods From January 1998, sixteen patients suffed from osteosarcoma(6 cases), chondrosarcoma(3 cases), gaint cell tumor(6 cases) and fibrosarcoma(1 case) arising from femur(5 cases), tibia(5 cases), humerus(3 cases), fibula(2 cases), radius(1 case).

1998年1月起，我院对16例肢体恶性骨肿瘤（按病理骨肉瘤6例，软骨肉瘤3例，骨巨细胞瘤6例，纤维肉瘤1例；按部位股骨5例，胫骨5例，肱骨3例，腓骨2例，桡骨1例）行骨肿瘤局部切除术及术中放疗加植骨。

Here we present a case of 21 year-old male who suffered from recurrent swelling in left side of mandible which had received surgery for ossifying fibroma in another hospital when he was 19 years old. Obvious facial asymmetry was noted but no sensory dysfunctions were detected. The lesion showed well-demarcated, multilocular radiolucency but radiopacity centrally. We applied segmental resection via extra-oral approach and reconstructed with anterior iliac crest bone graft. After removal of MMF in six week, the wound healed well and joint function was good without malocclusion. After follow-up of one year, no recurrences were noted.

本病例为－21岁之男性，在19岁时因为左下颚骨角区肿大在某医院接受外科手术处理，术后病理报告为骨化纤维瘤，因为复发的肿胀而来本院寻求治疗，临床检查并无疼痛及下唇区感觉异常的问题，放射线影像为周界清晰，多腔室放射透过性合并中央放射不透过性之不规则小块，手术方式为从口外颚下切线，做下颚骨片段式切除，并以肠骨脊海绵骨移植修补骨缺损加以颚间固定六周，术后伤口恢复及愈合良好，颚骨关系稳定无咬合异常的情况，无张口受限的问题。

Abstract］ objective to improve the diagnosis of non-ossifying fiboma by analysing its x-ray feature.methods plain x-ray films was performed in all patients.x-ray finding in 8 cases with pathologically-confirmed non-ossifying were analyzed.results the clinical symptom was mild,the lesions occurred usually at the metaphysis of the long bones,the affected bones included femur（n=4）,tibia（n=3）,humerus（n=1）.cortical type was seen in 5 cases,presenting as unilocular or multilacular transparent areas with in the cortex or tightly beneath the cortex,the lesion had a sclerotic margin.which was more obvious at the marrow side.medullary type was seen in 2 cases.the lesion was located at the center of the bone and grew centrally.the tumor was manifested as unilocular or multilocular.tramsparent area with sclerotic border and the bone cortex became thinner with slightly expanding on 11 sides.conclusion plain radiography is the elementally means to detect this disease.based on the typical x-ray signs of non-ossifying fibroma combined with clinical data,correct preoperative diagnosis can be made in most cases.

目的 探讨非骨化性纤维瘤的x线表现以提高诊断水平。方法所有病例均摄有x线平片，分析经病理证实的8例非骨化性纤维瘤。结果临床症状轻，好发于下肢长骨干骺端或骨干，股骨4例，胫骨3例，肱骨1例。皮质型5例，表现为皮质内或紧贴皮质下的单层或多层透亮区，病变向骨内发展进入髓腔，周围有致密硬化带环绕，以髓腔侧明显；髓质型2例，病灶在骨内中央发展，显示为单房或多房透亮区，边缘有硬化，骨皮质菲薄，轻微向周围膨隆。结论 x线为最基本的检查方法，典型病例x线平片结合临床症状即可明确诊断。

In this study, immunohistochemical staining was performed with antibodies against D2-40, S100, pankeratin, epithelial membrane antigen, brachyury, and glial fibrillary acidic protein in 4 cases of chordoid glioma, 6 skeletal myxoid chondrosarcomas, 10 chordoid meningiomas, 16 extraskeletal myxoid chondrosarcoma, 18 chordomas, 22 low-grade chondrosarcomas, and 27 enchondromas.

本研究中，我们给4例脊索样胶质瘤、6例骨的黏液样软骨肉瘤、10脊索样脑膜瘤、16例骨外黏液样软骨肉瘤、18例脊索瘤、22例低级别软骨肉瘤和27例内生性软骨瘤做了D2-40、S100、pankeratin、上皮膜抗原、brachyury和胶质纤维酸性蛋白的免疫组化染色。

Desmoplastic fibromas are rare, benign bone tumors that histologically resemble desmoid tumors of the soft tissue. Most examples of desmoplastic fibromas of the bone are discovered in patients younger than 30 years, and there is no gender predilection. A desmoplastic fibroma may involve any bone but is most frequent in the mandible.

致密纤维瘤是一种罕见的良性骨头肿瘤，在组织学和生物行为上和软组织的硬纤维瘤很相像，多半发生在小於30岁的年轻人，男女比例均等，好犯下颚骨或身体其它的长骨。

Results; MRI showed such components as fat,fibre,and liquid in teratoma,and large vessels in fibrolipomatous angioma;lytic bone destruction in giant cell tumor...

结果：畸胎瘤含脂肪、纤维和液体等成分；纤维脂肪血管瘤含有粗大血管；骨巨细胞瘤呈溶骨性破坏，1例在T2WI有液-液平面；神经源性肿瘤通过骶孔与骶管内病变相连，神经节母细胞瘤和神经外胚层瘤破坏骶孔；9例脊索瘤在T2WI有条状低信号纤维结构和高信号粘液基质；未分化癌和淋巴瘤T1WI呈略低信号，T2WI呈略高和较高信号；19例转移瘤有多处骨骼破坏，5例只有骶椎侵犯。

Objective To investigate the characteristics of bone benign fibrous histocytoma, nonossifying fibroma and metaphyseal fibrous defect.

目的 探讨骨良性纤维组织细胞瘤、非骨化性纤维瘤及干骺端纤维性缺损的特殊表现。

PPO gene was not detected in the multiple myelome、 malignant fibrous histiocytoma 、malignant lymphoma、malignant neurosarcoma、solitary plasmacytoma of bone、primitive neuroectodermal tumors、lipoma、 osteosarcoma and sarcoenchondroma.

PPO基因在多发性骨髓瘤、恶性纤维组织细胞瘤、恶性淋巴瘤、恶性神经肉瘤、孤立性浆细胞肉瘤、原始神经外胚瘤、脂肪瘤、骨及软骨肉瘤等肿瘤中没有表达。在骨巨细胞瘤中有微弱表达。

It is extremely necessary to find an ideal filling material for the treatment of benign bone defect, particularly those benign osteolytic defect in children with a comparatively large cavity.

为寻找良性骨缺损理想的充填材料，特别是修复儿童良性溶骨性较大的骨缺损，采用天然型无机骨充填良性溶骨性骨缺损5例，其中骨囊肿3例，纤维异样增殖症1例，非骨化性纤维瘤1例。

When Fas and c-myc protein were coexpressed in cytoplasm, a strong positive sign appeared in highly differentiated osteosarcoma, fibrous dysplasia of bone and osteoplast of bone callus, a weak sign was found in low-differentiated tumour cells and fibroblasts.

Fas和c-myc蛋白胞浆内阳性，在骨肉瘤的高分化细胞(骨母细胞型和软骨细胞型瘤细胞)和骨化性纤维瘤、骨纤维结构不良、骨痂组织中骨母细胞呈强表达；而在低分化瘤细胞和纤维母细胞则呈弱表达。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐